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2B0K
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Crystal structure of the DB921-D(CGCGAATTCGCG)2 complex.
分子名称: 2-(4'-AMIDINOBIPHENYL-4-YL)-1H-BENZIMIDAZOLE-5-AMIDINE, 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION
著者Miao, Y, Lee, M.P, Parkinson, G.N, Batista-Parra, A, Ismail, M.A, Neidle, S, Boykin, D.W, Wilson, W.D.
登録日2005-09-14
公開日2005-11-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Out-of-Shape DNA Minor Groove Binders: Induced Fit Interactions of Heterocyclic Dications with the DNA Minor Groove.
Biochemistry, 44, 2005
2B0L
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C-terminal DNA binding domain of transcriptional pleiotropic repressor CodY.
分子名称: GTP-sensing transcriptional pleiotropic repressor codY
著者Levdikov, V.M, Blagova, E, Joseph, P, Sonenshein, A.L, Wilkinson, A.J.
登録日2005-09-14
公開日2006-02-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Structure of CodY, a GTP- and Isoleucine-responsive Regulator of Stationary Phase and Virulence in Gram-positive Bacteria.
J.Biol.Chem., 281, 2006
2B0M
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Human dihydroorotate dehydrogenase bound to a novel inhibitor
分子名称: 3-AMIDO-5-BIPHENYL-BENZOIC ACID, Dihydroorotate dehydrogenase, mitochondrial, ...
著者Hurt, D.E, Sutton, A.E, Clardy, J.
登録日2005-09-14
公開日2005-09-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Brequinar derivatives and species-specific drug design for dihydroorotate dehydrogenase.
Bioorg.Med.Chem.Lett., 16, 2006
2B0O
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Crystal structure of UPLC1 GAP domain
分子名称: UPLC1, ZINC ION
著者Ismail, S, Shen, L, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2005-09-14
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Structural analysis of GAP and ankyrin domains of UPLC1
To be Published
2B0P
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truncated S. aureus LytM, P212121 crystal form
分子名称: ACETATE ION, CACODYLATE ION, Glycyl-glycine endopeptidase lytM, ...
著者Firczuk, M, Mucha, A, Bochtler, M.
登録日2005-09-14
公開日2006-01-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structures of active LytM.
J.Mol.Biol., 354, 2005
2B0Q
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Crystal Structure Of 3',5"-Aminoglycoside Phosphotransferase Type IIIa ADP Neomycin B Complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Aminoglycoside 3'-phosphotransferase, MAGNESIUM ION, ...
著者Fong, D.H, Berghuis, A.M.
登録日2005-09-14
公開日2005-09-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Substrate promiscuity of an aminoglycoside antibiotic resistance enzyme via target mimicry.
Embo J., 21, 2002
2B0R
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Crystal Structure of Cyclase-Associated Protein from Cryptosporidium parvum
分子名称: UNKNOWN ATOM OR ION, possible adenyl cyclase-associated protein
著者Tempel, W, Dong, A, Zhao, Y, Lew, J, Kozieradzki, I, Alam, Z, Melone, M, Wasney, G, Vedadi, M, Arrowsmith, C, Edwards, A, Weigelt, J, Sundstrom, M, Hui, R, Bochkarev, A, Artz, J, Structural Genomics Consortium (SGC)
登録日2005-09-14
公開日2005-09-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and function of a G-actin sequestering protein with a vital role in malaria oocyst development inside the mosquito vector
J.Biol.Chem., 151, 2010
2B0S
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Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with MN peptide
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, Fab 2219, ...
著者Stanfield, R.L, Gorny, M.K, Zolla-Pazner, S, Wilson, I.A.
登録日2005-09-14
公開日2006-07-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity.
J.Virol., 80, 2006
2B0T
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Structure of Monomeric NADP Isocitrate dehydrogenase
分子名称: MAGNESIUM ION, NADP Isocitrate dehydrogenase
著者Imabayashi, F, Aich, S, Prasad, L, Delbaere, L.T.
登録日2005-09-14
公開日2006-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Substrate-free structure of a monomeric NADP isocitrate dehydrogenase: An open conformation phylogenetic relationship of isocitrate dehydrogenase.
Proteins, 63, 2006
2B0U
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The Structure of the Follistatin:Activin Complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Follistatin, IRIDIUM (III) ION, ...
著者Thompson, T.B, Lerch, T.F, Cook, R.W, Woodruff, T.K, Jardetzky, T.S.
登録日2005-09-14
公開日2005-10-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Structure of the Follistatin:Activin Complex Reveals Antagonism of Both Type I and Type II Receptor Binding.
Dev.Cell, 9, 2005
2B0V
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NUDIX hydrolase from Nitrosomonas europaea.
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, NUDIX hydrolase, ...
著者Osipiuk, J, Skarina, T, Savchenko, A, Edwards, A, Joachimiak, A, MCSG, Midwest Center for Structural Genomics (MCSG)
登録日2005-09-14
公開日2005-09-27
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献X-ray structure of NUDIX hydrolase from Nitrosomonas europaea.
To be Published
2B0Y
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Solution Structure of a peptide mimetic of the fourth cytoplasmic loop of the G-protein coupled CB1 cannabinoid receptor
分子名称: Cannabinoid receptor 1
著者Grace, C.R, Cowsik, S.M, Shim, J.Y, Welsh, W.J, Howlett, A.C.
登録日2005-09-15
公開日2006-08-29
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Unique helical conformation of the fourth cytoplasmic loop of the CB1 cannabinoid receptor in a negatively charged environment.
J.Struct.Biol., 159, 2007
2B0Z
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Crystal structure of the protein-protein complex between F82I cytochrome c and cytochrome c peroxidase
分子名称: Cytochrome c iso-1, Cytochrome c peroxidase, mitochondrial, ...
著者Kang, S.A, Crane, B.R.
登録日2005-09-15
公開日2005-10-25
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Effects of interface mutations on association modes and electron-transfer rates between proteins
Proc.Natl.Acad.Sci.Usa, 102, 2005
2B10
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Crystal Structure of the Protein-Protein Complex between F82S cytochrome c and cytochrome c peroxidase
分子名称: Cytochrome c iso-1, Cytochrome c peroxidase, mitochondrial, ...
著者Kang, S.A, Crane, B.R.
登録日2005-09-15
公開日2005-10-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Effects of interface mutations on association modes and electron-transfer rates between proteins
Proc.Natl.Acad.Sci.Usa, 102, 2005
2B11
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Crystal structure of the protein-protein complex between F82W cytochrome c and cytochrome c peroxidase
分子名称: Cytochrome c iso-1, Cytochrome c peroxidase, mitochondrial, ...
著者Kang, S.A, Crane, B.R.
登録日2005-09-15
公開日2005-10-25
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Effects of interface mutations on association modes and electron-transfer rates between proteins
Proc.Natl.Acad.Sci.Usa, 102, 2005
2B12
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Crystal structure of the protein-protein complex between F82Y cytochrome c and cytochrome c peroxidase
分子名称: Cytochrome c iso-1, Cytochrome c peroxidase, mitochondrial, ...
著者Kang, S.A, Crane, B.R.
登録日2005-09-15
公開日2005-10-25
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Effects of interface mutations on association modes and electron-transfer rates between proteins
Proc.Natl.Acad.Sci.Usa, 102, 2005
2B13
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Truncated S. aureus LytM, P41 crystal form
分子名称: Glycyl-glycine endopeptidase lytM, L(+)-TARTARIC ACID, ZINC ION
著者Firczuk, M, Mucha, A, Bochtler, M.
登録日2005-09-15
公開日2006-01-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structures of active LytM.
J.Mol.Biol., 354, 2005
2B14
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The crystal structure of 2,4-dinitrophenol in complex with the amyloidogenic variant Transthyretin Leu 55 Pro
分子名称: 2,4-DINITROPHENOL, Transthyretin
著者Morais-de-Sa, E, Neto-Silva, R.M, Pereira, P.J, Saraiva, M.J, Damas, A.M.
登録日2005-09-15
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The binding of 2,4-dinitrophenol to wild-type and amyloidogenic transthyretin
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
2B15
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The crystal structure of 2,4-dinitrophenol in complex with human transthyretin
分子名称: 2,4-DINITROPHENOL, SULFATE ION, Transthyretin
著者Morais-de-Sa, E, Neto-Silva, R.M, Pereira, P.J, Saraiva, M.J, Damas, A.M.
登録日2005-09-15
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The binding of 2,4-dinitrophenol to wild-type and amyloidogenic transthyretin
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
2B16
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The crystal structure of 2,4-dinitrophenol in complex with the amyloidogenic variant Transthyretin Tyr78Phe
分子名称: 2,4-DINITROPHENOL, Transthyretin
著者Morais-de-Sa, E, Neto-Silva, R.M, Pereira, P.J, Saraiva, M.J, Damas, A.M.
登録日2005-09-15
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The binding of 2,4-dinitrophenol to wild-type and amyloidogenic transthyretin
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
2B17
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Specific binding of non-steroidal anti-inflammatory drugs (NSAIDs) to phospholipase A2: Crystal structure of the complex formed between phospholipase A2 and diclofenac at 2.7 A resolution:
分子名称: 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
著者Singh, N, Jabeen, T, Sharma, S, Singh, T.P.
登録日2005-09-15
公開日2005-10-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Specific binding of non-steroidal anti-inflammatory drugs (NSAIDs) to phospholipase A2: structure of the complex formed between phospholipase A2 and diclofenac at 2.7 A resolution.
Acta Crystallogr.,Sect.D, 62, 2006
2B18
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N-terminal GAF domain of transcriptional pleiotropic repressor CodY.
分子名称: GTP-sensing transcriptional pleiotropic repressor codY, ISOLEUCINE
著者Levdikov, V.M, Blagova, E, Joseph, P, Sonenshein, A.L, Wilkinson, A.J.
登録日2005-09-15
公開日2006-02-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Structure of CodY, a GTP- and Isoleucine-responsive Regulator of Stationary Phase and Virulence in Gram-positive Bacteria.
J.Biol.Chem., 281, 2006
2B19
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Solution Structure of mammalian tachykinin peptide, Neuropeptide K
分子名称: Neuropeptide K
著者Dike, A, Cowsik, S.M.
登録日2005-09-15
公開日2006-09-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of neuropeptide k bound to dodecylphosphocholine micelles
Biochemistry, 45, 2006
2B1A
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Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with UG1033 peptide
分子名称: Fab 2219, heavy chain, light chain, ...
著者Stanfield, R.L, Gorny, M.K, Zolla-Pazner, S, Wilson, I.A.
登録日2005-09-15
公開日2006-07-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.348 Å)
主引用文献Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity.
J.Virol., 80, 2006
2B1B
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5'-D(*GP*CP*GP*TP*GP*GP*GP*CP*AP*C)-3' Zif268 binding site
分子名称: 5'-D(*GP*CP*GP*TP*GP*GP*GP*CP*AP*C)-3', 5'-D(*GP*TP*GP*CP*CP*CP*AP*CP*GP*C)-3', MAGNESIUM ION
著者Berman, H.M, Napoli, A.A.
登録日2005-09-15
公開日2005-09-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Signatures of protein-DNA recognition in free DNA binding sites.
J.Mol.Biol., 386, 2009

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