2B0K

Crystal structure of the DB921-D(CGCGAATTCGCG)2 complex.

Summary for 2B0K

• Entry DOI: 10.2210/pdb2b0k/pdb
• Related: 2DBE
• Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION, 2-(4'-AMIDINOBIPHENYL-4-YL)-1H-BENZIMIDAZOLE-5-AMIDINE, ... (4 entities in total)
• Functional Keywords: nucleic acids, dna, double helix, minor groove, dna minor groove binder, dna minor groove-ligand complex, db921, a2t2, dickerson and drew dna, crystal structure of b-dna, dna-drug complex, magnesium-water complex, hydrated magnesium, dna hydration.
• Total number of polymer chains: 2
• Total formula weight: 7705.50

Authors

Miao, Y.,Lee, M.P.,Parkinson, G.N.,Batista-Parra, A.,Ismail, M.A.,Neidle, S.,Boykin, D.W.,Wilson, W.D. (deposition date: 2005-09-14, release date: 2005-11-22, Last modification date: 2023-08-23)

• Primary citation: Miao, Y.,Lee, M.P.,Parkinson, G.N.,Batista-Parra, A.,Ismail, M.A.,Neidle, S.,Boykin, D.W.,Wilson, W.D.; Out-of-Shape DNA Minor Groove Binders: Induced Fit Interactions of Heterocyclic Dications with the DNA Minor Groove.; Biochemistry, 44:14701-14708, 2005; PubMed: 16274217; DOI: 10.1021/bi051791q

Experimental method

X-RAY DIFFRACTION (1.64 Å)