PDB: 46188 件ウェブページステータス検索Chemie searchBIRD

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6MD0	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Oleic Acid 分子名称: OLEIC ACID, Peroxisome proliferator-activated receptor gamma 著者 Shang, J, Kojetin, D.J. 登録日 2018-09-03 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma. Elife, 7, 2018
5V70	Crystal structure of N102A mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2017-03-17 公開日 2018-03-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Crystal structure of N102A mutant of human macrophage migration inhibitory factor To Be Published
1DUE	CRYSTAL STRUCTURE OF EXFOLIATIVE TOXIN A S195A MUTANT 分子名称: EXFOLIATIVE TOXIN A 著者 Papageorgiou, A.C, Plano, L.R.W, Collins, C.M, Acharya, K.R. 登録日 2000-01-17 公開日 2003-01-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural similarities and differences in Staphylococcus aureus exfoliative Toxins A and B as revealed by their crystal structures Protein Sci., 9, 2000
1DUT	FIV DUTP PYROPHOSPHATASE 分子名称: DUTP PYROPHOSPHATASE, MAGNESIUM ION 著者 Prasad, G.S, Stura, E.A, Mcree, D.E, Laco, G.S, Hasselkus-Light, C, Elder, J.H, Stout, C.D. 登録日 1996-09-15 公開日 1997-01-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of dUTP pyrophosphatase from feline immunodeficiency virus. Protein Sci., 5, 1996
1DW9	Structure of cyanase reveals that a novel dimeric and decameric arrangement of subunits is required for formation of the enzyme active site 分子名称: CHLORIDE ION, CYANATE LYASE, SULFATE ION 著者 Walsh, M.A, Otwinowski, Z, Perrakis, A, Anderson, P.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 1999-12-03 公開日 2000-05-16 最終更新日 2019-08-21 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure of Cyanase Reveals that a Novel Dimeric and Decameric Arrangement of Subunits is Required for Formation of the Enzyme Active Site Structure, 8, 2000
7CXK	The ligand-free structure of human PPARgamma LBD R288H mutant in the presence of the SRC-1 coactivator peptide 分子名称: 16-mer peptide from Nuclear receptor coactivator 1, MALONATE ION, Peroxisome proliferator-activated receptor gamma 著者 Jang, D.M, Han, B.W. 登録日 2020-09-01 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The ligand-free structure of human PPARgamma LBD To Be Published
7CXH	The ligand-free structure of human PPARgamma LBD Q286E mutant in the presence of the SRC-1 coactivator peptide 分子名称: 16-mer peptide from Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma 著者 Jang, D.M, Han, B.W. 登録日 2020-09-01 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The ligand-free structure of human PPARgamma LBD To Be Published
7CXL	The ligand-free structure of human PPARgamma LBD S289C mutant in the presence of the SRC-1 coactivator peptide 分子名称: 16-mer peptide from Nuclear receptor coactivator 1, MALONIC ACID, Peroxisome proliferator-activated receptor gamma 著者 Jang, D.M, Han, B.W. 登録日 2020-09-01 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The ligand-free structure of human PPARgamma LBD To Be Published
7WQQ	Retinoic acid receptor alpha mutant - N299H 分子名称: 4-[(E)-3-(3,5-ditert-butylphenyl)-3-oxidanylidene-prop-1-enyl]benzoic acid, Peptide from Nuclear receptor coactivator 1, Retinoic acid receptor alpha 著者 Huang, X.X, Ng, L.M, Teh, B.T. 登録日 2022-01-25 公開日 2023-01-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Effects of breast fibroepithelial tumor associated retinoic acid receptor alpha ligand binding domain mutations on receptor function and retinoid signaling To Be Published
1DVG	CRYSTAL STRUCTURE OF RAT HEME OXYGENASE-1 IN COMPLEX WITH HEME; SELELENO-METHIONINE DERIVATIVE, MUTATED AT M51T,M93L,M155L,M191L. 分子名称: HEME OXYGENASE-1, PROTOPORPHYRIN IX CONTAINING FE 著者 Sugishima, M, Omata, Y, Kakuta, Y, Sakamoto, H, Noguchi, M, Fukuyama, K. 登録日 2000-01-20 公開日 2000-04-12 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of rat heme oxygenase-1 in complex with heme. FEBS Lett., 471, 2000
7CXI	The ligand-free structure of human PPARgamma LBD F287Y mutant in the presence of the SRC-1 coactivator peptide 分子名称: 16-mer peptide from Nuclear receptor coactivator 1, MALONATE ION, Peroxisome proliferator-activated receptor gamma 著者 Jang, D.M, Han, B.W. 登録日 2020-09-01 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The ligand-free structure of human PPARgamma LBD To Be Published
7CXF	The ligand-free structure of human PPARgamma LBD C285Y mutant in the presence of the SRC-1 coactivator peptide 分子名称: 16-mer peptide from Nuclear receptor coactivator 1, MALONIC ACID, Peroxisome proliferator-activated receptor gamma 著者 Jang, D.M, Han, B.W. 登録日 2020-09-01 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The ligand-free structure of human PPARgamma LBD To Be Published
7CXJ	The ligand-free structure of human PPARgamma LBD R288C mutant in the presence of the SRC-1 coactivator peptide 分子名称: 16-mer peptide from Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma 著者 Jang, D.M, Han, B.W. 登録日 2020-09-01 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 The ligand-free structure of human PPARgamma LBD To Be Published
7CXG	The ligand-free structure of human PPARgamma LBD Q286E mutant 分子名称: GLYCEROL, Peroxisome proliferator-activated receptor gamma 著者 Jang, D.M, Han, B.W. 登録日 2020-09-01 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 The ligand-free structure of human PPARgamma LBD To Be Published
6SYT	Structure of the SMG1-SMG8-SMG9 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... 著者 Gat, Y, Schuller, J.M, Conti, E. 登録日 2019-10-01 公開日 2019-12-11 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 InsP6binding to PIKK kinases revealed by the cryo-EM structure of an SMG1-SMG8-SMG9 complex. Nat.Struct.Mol.Biol., 26, 2019
1E0A	Cdc42 complexed with the GTPase binding domain of p21 activated kinase 分子名称: Cell division control protein 42 homolog, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Morreale, A, Venkatesan, M, Mott, H.R, Owen, D, Nietlispach, D, Lowe, P.N, Laue, E.D. 登録日 2000-03-16 公開日 2000-04-18 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure of Cdc42 Bound to the Gtpase Binding Domian of Pak Nat.Struct.Biol., 7, 2000
6FHI	Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 19-mer serine 5 phosphorylated Pol II CTD peptide with a truncated linker. 分子名称: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Lukarska, M, Cusack, S. 登録日 2018-01-14 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Towards New Anti-Influenza Therapeutics: Structure-Activity Relationships in the Interaction between Heterotrimeric Influenza Polymerase and Pol II C-terminal domain To Be Published
6B2C	Macrophage Migration Inhibitory Factor in Complex with a Naphthyridinone Inhibitor (4b) 分子名称: Macrophage migration inhibitory factor, SULFATE ION, {2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-8-oxo-1,7-naphthyridin-7(8H)-yl}acetic acid 著者 Krimmer, S.G, Robertson, M.J, Jorgensen, W.L. 登録日 2017-09-19 公開日 2018-01-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Adding a Hydrogen Bond May Not Help: Naphthyridinone vs Quinoline Inhibitors of Macrophage Migration Inhibitory Factor. ACS Med Chem Lett, 8, 2017
6FH4	CtsR C-terminal domain with bound phospho-arginine 分子名称: PHOSPHATE ION, Transcriptional regulator CtsR, phospho-arginine 著者 Suskiewicz, M.J, Clausen, T. 登録日 2018-01-12 公開日 2019-02-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Structure of McsB, a protein kinase for regulated arginine phosphorylation. Nat.Chem.Biol., 15, 2019
1E2P	Thymidine kinase, DHBT 分子名称: 6-[3-HYDROXY-2-(HYDROXYMETHYL)PROPYL]-5-METHYL-2,4(1H,3H)-PYRIMIDINEDIONE, SULFATE ION, THYMIDINE KINASE 著者 Schulz, G.E, Kessler, U. 登録日 2000-05-23 公開日 2001-04-26 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The Effect of Substrate Binding on the Conformation and Structural Stability of Herpes Simplex Virus Type 1 Thymidine Kinase Protein Sci., 10, 2001
3OP5	Human vaccinia-related kinase 1 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Serine/threonine-protein kinase VRK1, ... 著者 Allerston, C.K, Uttarkar, S, Savitsky, P, Elkins, J.M, Filippakopoulos, P, Krojer, T, Rellos, P, Fedorov, O, Eswaran, J, Brenner, B, Keates, T, Das, S, King, O, Chalk, R, Berridge, G, von Delft, F, Gileadi, O, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2010-08-31 公開日 2010-09-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations. Sci Rep, 7, 2017
1DWK	STRUCTURE OF CYANASE WITH THE DI-ANION OXALATE BOUND AT THE ENZYME ACTIVE SITE 分子名称: CYANATE HYDRATASE, OXALATE ION, SULFATE ION 著者 Walsh, M.A, Otwinowski, Z, Perrakis, A, Anderson, P.M, Joachimiak, A. 登録日 1999-12-07 公開日 2000-05-16 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure of Cyanase Reveals that a Novel Dimeric and Decameric Arrangement of Subunits is Required for Formation of the Enzyme Active Site. Structure, 8, 2000
5UMJ	Crystal structure of H62A mutant of human macrophage migration inhibitory factor 分子名称: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, SULFATE ION 著者 Pantouris, G, Lolis, E. 登録日 2017-01-27 公開日 2018-02-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel. Cell Chem Biol, 27, 2020
6CB5	Macrophage Migration Inhibitory Factor in complex with a Pyrazole Inhibitor (8g) 分子名称: 2-[(naphthalen-2-yl)oxy]-5-(1H-pyrazol-4-yl)benzoic acid, Macrophage migration inhibitory factor, SULFATE ION 著者 Krimmer, S.G, Robertson, M.J, Jorgensen, W.L. 登録日 2018-02-02 公開日 2018-04-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor. ChemMedChem, 13, 2018
6FGQ	Ligand complex of RORg LBD 分子名称: Nuclear receptor ROR-gamma, methyl 4-[[3-[5-[2-(4-ethylsulfonylphenyl)ethanoylamino]thiophen-3-yl]pyridin-2-yl]oxymethyl]benzoate 著者 Xue, Y, Aagaard, A, Narjes, F. 登録日 2018-01-11 公開日 2018-08-22 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Potent and Orally Bioavailable Inverse Agonists of ROR gamma t Resulting from Structure-Based Design. J. Med. Chem., 61, 2018

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