PDB: 45118 件ウェブページステータス検索Chemie searchBIRD

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7OV2	Crystal structure of pig purple acid phosphatase in complex with L-glutamine, (poly)ethylene glycol fragments and glycerol 分子名称: 1,2-ETHANEDIOL, CITRIC ACID, FE (III) ION, ... 著者 Feder, D, McGeary, R.P, Guddat, L.W, Schenk, G. 登録日 2021-06-14 公開日 2022-01-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Rational Design of Potent Inhibitors of a Metallohydrolase Using a Fragment-Based Approach. Chemmedchem, 16, 2021
6Z5X	The RSL - sulfonato-calix[8]arene complex, P213 form, acetate pH 4.8 分子名称: Fucose-binding lectin protein, SODIUM ION, SULFATE ION, ... 著者 Engilberge, S, Ramberg, K, Crowley, P.B. 登録日 2020-05-27 公開日 2021-04-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 Facile Fabrication of Protein-Macrocycle Frameworks. J.Am.Chem.Soc., 143, 2021
6Z6C	Crystal structurel of FleA lectin in complex with a monovalent inhibitor 分子名称: 4-((1-(2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methoxy)benzyl-a-L-thiofucoside, Fucose-specific lectin, GLYCEROL, ... 著者 Varrot, A. 登録日 2020-05-28 公開日 2021-04-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Hexavalent thiofucosides to probe the role of the Aspergillus fumigatus lectin FleA in fungal pathogenicity. Org.Biomol.Chem., 19, 2021
4KYV	Crystal Structure of dehalogenase HaloTag2 with HALTS at the resolution 1.8A. Northeast Structural Genomics Consortium (NESG) Target OR150 分子名称: N-(2-ethoxy-3,5-dimethylbenzyl)-1H-tetrazol-5-amine, SODIUM ION, dehalogenase HaloTag2 著者 Kuzin, A, Lew, S, Seetharaman, J, Maglaqui, M, Xiao, R, Kohan, E, Wang, H, Everett, J.K, Acton, T.B, Kornhaber, G, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2013-05-29 公開日 2013-07-24 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.796 Å) 主引用文献 Northeast Structural Genomics Consortium Target OR150 To be Published
6IVO	Crystal structure of a membrane protein P208A 分子名称: 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ... 著者 Kittredge, A, Fukuda, F, Zhang, Y, Yang, T. 登録日 2018-12-04 公開日 2019-11-06 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations. Commun Biol, 2, 2019
5L3G	LSD1-CoREST1 in complex with polymyxin E (colistin) 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A, REST corepressor 1, ... 著者 Speranzini, V, Rotili, D, Ciossani, G, Pilotto, S, Forgione, M, Lucidi, A, Forneris, F, Velankar, S, Mai, A, Mattevi, A. 登録日 2016-04-10 公開日 2016-09-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features. Sci Adv, 2, 2016
7OP6	Bacteroides thetaiotaomicron mannosidase GH2 with beta-manno-configured cyclophellitol aziridine 分子名称: (1~{R},2~{R},3~{S},4~{R},5~{R},6~{R})-5-(hydroxymethyl)-7-azabicyclo[4.1.0]heptane-2,3,4-triol, 1,2-ETHANEDIOL, BROMIDE ION, ... 著者 McGregor, N.G.S, Beenakker, T.J.M, Kuo, C, Wong, C, Offen, W.A, Armstrong, Z, Codee, J.D.C, Aerts, J.M.F.G, Florea, B.I, Overkleeft, H.S, Davies, G.J. 登録日 2021-05-29 公開日 2022-05-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Synthesis of broad-specificity activity-based probes for exo -beta-mannosidases. Org.Biomol.Chem., 20, 2022
5L26	Structure of CNTnw in an inward-facing substrate-bound state 分子名称: 2-{[(4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]methyl}-2-octyldecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, Nucleoside permease, SODIUM ION, ... 著者 Hirschi, M, Johnson, Z.L, Lee, S.-Y. 登録日 2016-07-31 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Visualizing multistep elevator-like transitions of a nucleoside transporter. Nature, 545, 2017
4LRT	Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site 分子名称: 4-hydroxy-2-oxovalerate aldolase, Acetaldehyde dehydrogenase, COENZYME A, ... 著者 Fischer, B, Branlant, G, Talfournier, F, Gruez, A. 登録日 2013-07-20 公開日 2013-09-04 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site To be Published
6IVQ	Crystal structure of a membrane protein S19A 分子名称: 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ... 著者 Kittredge, A, Fukuda, F, Zhang, Y, Yang, T. 登録日 2018-12-04 公開日 2019-11-06 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations. Commun Biol, 2, 2019
5L6Q	Refolded AL protein from cardiac amyloidosis 分子名称: CARBONATE ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Annamalai, K, Liberta, F, Vielberg, M.-T, Lilie, H, Guehrs, K.-H, Schierhorn, A, Koehler, R, Schmidt, A, Haupt, C, Hegenbart, O, Schoenland, S, Groll, M, Faendrich, M. 登録日 2016-05-31 公開日 2017-05-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Common Fibril Structures Imply Systemically Conserved Protein Misfolding Pathways In Vivo. Angew. Chem. Int. Ed. Engl., 56, 2017
4M4S	Gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus in complex with GDP and formate ion mimic aIF2gamma*GDP*Pi complex (a formate ion substitutes for Pi) 分子名称: FORMIC ACID, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Nikonov, O.S, Stolboushkina, E.A, Arkhipova, V.I, Gabdulkhakov, A.G, Nikulin, A.D, Garber, M.B, Nikonov, S.V. 登録日 2013-08-07 公開日 2014-03-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.251 Å) 主引用文献 Conformational transitions in the gamma subunit of the archaeal translation initiation factor 2. Acta Crystallogr.,Sect.D, 70, 2014
7OW7	EIF6-bound large subunit of the human ribosome 分子名称: 28S rRNA, 5.8S ribosomal RNA, 5S rRNA, ... 著者 Faille, A, Warren, A.J. 登録日 2021-06-16 公開日 2022-10-05 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Structure of human EIF6-bound large ribosomal subunit To Be Published
3QW8	Crystal structure of the protease domain of Botulinum Neurotoxin Serotype A with a peptide inhibitor CRGC 分子名称: 1,2-ETHANEDIOL, Botulinum neurotoxin type A, SODIUM ION, ... 著者 Kumaran, D, Swaminathan, S. 登録日 2011-02-27 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Peptide inhibitors of botulinum neurotoxin serotype A: design, inhibition, cocrystal structures, structure-activity relationship and pharmacophore modeling. Acta Crystallogr.,Sect.D, 68, 2012
3PIP	Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit 分子名称: 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Belousoff, M.J, Shapira, T, Bashan, A, Zimmerman, E, Kinashi, H, Rozenberg, H, Yonath, A. 登録日 2010-11-07 公開日 2011-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit. Proc.Natl.Acad.Sci.USA, 108, 2011
7P4J	Crystal structure of Autotaxin and tetrahydrocannabinol 分子名称: (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7alpha-hydroxycholesterol, ... 著者 Eymery, M.C, McCarthy, A.A, Hausmann, J. 登録日 2021-07-11 公開日 2022-12-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Linking medicinal cannabis to autotaxin-lysophosphatidic acid signaling. Life Sci Alliance, 6, 2023
6IX8	The structure of LepI C52A in complex with SAM and its substrate analogue 分子名称: (1R,2R,4aS,8S,8aR)-2,8-dimethyl-5'-phenyl-4a,5,6,7,8,8a-hexahydro-2H,2'H-spiro[naphthalene-1,3'-pyridine]-2',4'(1'H)-dione, 1,2-ETHANEDIOL, ACETATE ION, ... 著者 Cai, Y, Ohashi, M, Hai, Y, Tang, Y, Zhou, J. 登録日 2018-12-09 公開日 2019-07-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.659 Å) 主引用文献 Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI. Nat.Chem., 11, 2019
3QW7	Crystal structure of the protease domain of Botulinum Neurotoxin Serotype A with a peptide inhibitor RRFC 分子名称: Botulinum neurotoxin type A, SODIUM ION, SULFATE ION, ... 著者 Kumaran, D, Swaminathan, S. 登録日 2011-02-27 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Peptide inhibitors of botulinum neurotoxin serotype A: design, inhibition, cocrystal structures, structure-activity relationship and pharmacophore modeling. Acta Crystallogr.,Sect.D, 68, 2012
6J05	Structures of two ArsR As(III)-responsive repressors: implications for the mechanism of derepression 分子名称: ARSENIC, SODIUM ION, Transcriptional regulator ArsR 著者 Prabaharan, C, Kandavelu, P, Packianathan, C, Rosen, P.B, Thiyagarajan, S. 登録日 2018-12-21 公開日 2019-07-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Structures of two ArsR As(III)-responsive transcriptional repressors: Implications for the mechanism of derepression. J.Struct.Biol., 207, 2019
7PJY	Structure of the 70S-EF-G-GDP ribosome complex with tRNAs in chimeric state 1 (CHI1-EF-G-GDP) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N. 登録日 2021-08-24 公開日 2021-10-20 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural mechanism of GTPase-powered ribosome-tRNA movement. Nat Commun, 12, 2021
3QW6	Crystal structure of the protease domain of Botulinum Neurotoxin Serotype A with a peptide inhibitor RYGC 分子名称: Botulinum neurotoxin type A, SODIUM ION, SULFATE ION, ... 著者 Kumaran, D, Swaminathan, S. 登録日 2011-02-26 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Peptide inhibitors of botulinum neurotoxin serotype A: design, inhibition, cocrystal structures, structure-activity relationship and pharmacophore modeling. Acta Crystallogr.,Sect.D, 68, 2012
5M07	Crystal structure of Mycobacterium tuberculosis PknI kinase domain, C20A mutant 分子名称: SODIUM ION, Serine/threonine-protein kinase PknI 著者 Lisa, M.N, Wagner, T, Alexandre, M, Barilone, N, Raynal, B, Alzari, P.M, Bellinzoni, M. 登録日 2016-10-03 公開日 2017-01-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation. FEBS J., 284, 2017
5M09	Crystal structure of Mycobacterium tuberculosis PknI kinase domain, C20A_R136N double mutant 分子名称: SODIUM ION, Serine/threonine-protein kinase PknI 著者 Lisa, M.N, Wagner, T, Alexandre, M, Barilone, N, Raynal, B, Alzari, P.M, Bellinzoni, M. 登録日 2016-10-03 公開日 2017-01-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation. FEBS J., 284, 2017
7PJS	Structure of the 70S ribosome with tRNAs in the classical pre-translocation state and apramycin (C) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N. 登録日 2021-08-24 公開日 2021-10-20 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.35 Å) 主引用文献 Structural mechanism of GTPase-powered ribosome-tRNA movement Nat Commun, 12, 2021
5M1D	Crystal structure of N-terminally tagged UbiD from E. coli reconstituted with prFMN cofactor 分子名称: 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase, MANGANESE (II) ION, ... 著者 Marshall, S.A, Leys, D. 登録日 2016-10-07 公開日 2017-01-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Oxidative Maturation and Structural Characterization of Prenylated FMN Binding by UbiD, a Decarboxylase Involved in Bacterial Ubiquinone Biosynthesis. J. Biol. Chem., 292, 2017

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