6Z6C
Crystal structurel of FleA lectin in complex with a monovalent inhibitor
This is a non-PDB format compatible entry.
Summary for 6Z6C
Entry DOI | 10.2210/pdb6z6c/pdb |
Descriptor | Fucose-specific lectin, 4-((1-(2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methoxy)benzyl-a-L-thiofucoside, GLYCEROL, ... (6 entities in total) |
Functional Keywords | lectin, antiadhesive, fucose binding, sugar binding protein |
Biological source | Aspergillus fumigatus Af293 |
Total number of polymer chains | 2 |
Total formula weight | 74865.34 |
Authors | Varrot, A. (deposition date: 2020-05-28, release date: 2021-04-07, Last modification date: 2024-01-24) |
Primary citation | Dussouy, C.,Lalys, P.A.,Cabanettes, A.,Lehot, V.,Deniaud, D.,Gillon, E.,Balloy, V.,Varrot, A.,Gouin, S.G. Hexavalent thiofucosides to probe the role of the Aspergillus fumigatus lectin FleA in fungal pathogenicity. Org.Biomol.Chem., 19:3234-3240, 2021 Cited by PubMed: 33885578DOI: 10.1039/d1ob00152c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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