6Z6C

Crystal structurel of FleA lectin in complex with a monovalent inhibitor

This is a non-PDB format compatible entry.

Summary for 6Z6C

• Entry DOI: 10.2210/pdb6z6c/pdb
• Descriptor: Fucose-specific lectin, 4-((1-(2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methoxy)benzyl-a-L-thiofucoside, GLYCEROL, ... (6 entities in total)
• Functional Keywords: lectin, antiadhesive, fucose binding, sugar binding protein
• Biological source: Aspergillus fumigatus Af293
• Total number of polymer chains: 2
• Total formula weight: 74865.34

Authors

Varrot, A. (deposition date: 2020-05-28, release date: 2021-04-07, Last modification date: 2024-01-24)

• Primary citation: Dussouy, C.,Lalys, P.A.,Cabanettes, A.,Lehot, V.,Deniaud, D.,Gillon, E.,Balloy, V.,Varrot, A.,Gouin, S.G.; Hexavalent thiofucosides to probe the role of the Aspergillus fumigatus lectin FleA in fungal pathogenicity.; Org.Biomol.Chem., 19:3234-3240, 2021; PubMed: 33885578; DOI: 10.1039/d1ob00152c

Experimental method

X-RAY DIFFRACTION (1.4 Å)