5M07

Crystal structure of Mycobacterium tuberculosis PknI kinase domain, C20A mutant

Summary for 5M07

• Entry DOI: 10.2210/pdb5m07/pdb
• Descriptor: Serine/threonine-protein kinase PknI, SODIUM ION (3 entities in total)
• Functional Keywords: tuberculosis, kinase, signalling, transferase, signaling protein
• Biological source: Mycobacterium tuberculosis H37Rv
• Cellular location: Cytoplasm : P9WI69
• Total number of polymer chains: 2
• Total formula weight: 59322.81

Authors

Lisa, M.N.,Wagner, T.,Alexandre, M.,Barilone, N.,Raynal, B.,Alzari, P.M.,Bellinzoni, M. (deposition date: 2016-10-03, release date: 2017-01-11, Last modification date: 2024-01-17)

• Primary citation: Lisa, M.N.,Wagner, T.,Alexandre, M.,Barilone, N.,Raynal, B.,Alzari, P.M.,Bellinzoni, M.; The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation.; FEBS J., 284:602-614, 2017; PubMed: 28054744; DOI: 10.1111/febs.14003

Experimental method

X-RAY DIFFRACTION (2.5 Å)