PDB: 22592 件ウェブページステータス検索Chemie searchBIRD

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3IU7	M. tuberculosis methionine aminopeptidase with Mn inhibitor A02 分子名称: 5-(2-CHLOROPHENYL)FURAN-2-CARBOXYLIC ACID, CHLORIDE ION, MANGANESE (II) ION, ... 著者 Ye, Q.Z, Lu, J.P. 登録日 2009-08-30 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase J.Med.Chem., 53, 2010
1U13	Crystal structure analysis of the C37L/C151T/C442A-triple mutant of CYP51 from Mycobacterium tuberculosis 分子名称: Cytochrome P450 51, PROTOPORPHYRIN IX CONTAINING FE 著者 Podust, L.M, Yermalitskaya, L.V, Kim, Y, Waterman, M.R. 登録日 2004-07-14 公開日 2004-07-27 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Crystal structure analysis of the C37L/C151T/C442A-triple mutant of CYP51 from Mycobacterium tuberculosis To be published
3IU9	M. tuberculosis methionine aminopeptidase with Ni inhibitor T07 分子名称: 5-[(2,4-dichlorobenzyl)sulfanyl]-4H-1,2,4-triazol-3-amine, CHLORIDE ION, Methionine aminopeptidase, ... 著者 Ye, Q.Z, Lu, J.P. 登録日 2009-08-30 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase J.Med.Chem., 53, 2010
3IU8	M. tuberculosis methionine aminopeptidase with Ni inhibitor T03 分子名称: 3-[(4-fluorobenzyl)sulfanyl]-4H-1,2,4-triazole, CHLORIDE ION, Methionine aminopeptidase, ... 著者 Ye, Q.Z, Lu, J.P. 登録日 2009-08-30 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase J.Med.Chem., 53, 2010
1XKF	Crystal structure of Hypoxic Response Protein I (HRPI) with two coordinated zinc ions 分子名称: ZINC ION, hypothetical protein RV2626C 著者 Sharpe, M.L, Baker, E.N, Lott, J.S. 登録日 2004-09-28 公開日 2005-10-11 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The structure and unusual protein chemistry of hypoxic response protein 1, a latency antigen and highly expressed member of the DosR regulon in Mycobacterium tuberculosis J.Mol.Biol., 383, 2008
3G5F	Crystallographic analysis of cytochrome P450 cyp121 分子名称: Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION 著者 Belin, P, Le Du, M.H, Gondry, M. 登録日 2009-02-05 公開日 2009-04-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 106, 2009
2IJ5	Crystal structure of cytochrome P450 CYP121, P212121 space group 分子名称: Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION 著者 Roujeinikova, A, Leys, D. 登録日 2006-09-29 公開日 2006-11-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of the Mycobacterium tuberculosis P450 CYP121-fluconazole complex reveals new azole drug-P450 binding mode. J.Biol.Chem., 281, 2006
3G5H	Crystallographic analysis of cytochrome P450 cyp121 分子名称: (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazine-2,5-dione, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Belin, P, Le Du, M.H, Gondry, M. 登録日 2009-02-05 公開日 2009-04-21 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 106, 2009
1Y5H	Crystal structure of truncated Se-Met Hypoxic Response Protein I (HRPI) 分子名称: hypothetical protein RV2626C 著者 Sharpe, M.L, Baker, E.N, Lott, J.S. 登録日 2004-12-02 公開日 2005-11-15 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The structure and unusual protein chemistry of hypoxic response protein 1, a latency antigen and highly expressed member of the DosR regulon in Mycobacterium tuberculosis J.Mol.Biol., 383, 2008
1SM8	M. tuberculosis dUTPase complexed with chromium and dUTP 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHROMIUM ION, DEOXYURIDINE-5'-TRIPHOSPHATE, ... 著者 Sawaya, M.R, Chan, S, Segelke, B, Lekin, T, Krupka, H, Cho, U.S, Kim, M.-Y, So, M, Kim, C.-Y, Naranjo, C.M, Rogers, Y.C, Park, M.S, Waldo, G.S, Pashkov, I, Cascio, D, Yeates, T.O, Perry, J.L, Terwilliger, T.C, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) 登録日 2004-03-08 公開日 2004-03-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism. J.Mol.Biol., 341, 2004
2XJA	Structure of MurE from M.tuberculosis with dipeptide and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE, ... 著者 Basavannacharya, C, Moody, P.R, Bhakta, S, Keep, N. 登録日 2010-07-03 公開日 2010-08-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Essential Residues for the Enzyme Activity of ATP-Dependent Mure Ligase from Mycobacterium Tuberculosis. Protein Cell, 1, 2010
4KMC	Structure analysis of M. Tuberculosis rRNA transcriptional regulator CarD and its interaction with T. Aquaticus RNA polymerase-BETA1 domain 分子名称: RNA polymerase-binding transcription factor CarD 著者 Gangwar, S.P, Meena, S.R, Saxena, A.K. 登録日 2013-05-08 公開日 2014-02-19 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structure of the carboxy-terminal domain of Mycobacterium tuberculosis CarD protein: an essential rRNA transcriptional regulator. Acta Crystallogr.,Sect.F, 70, 2014
1MC9	STREPROMYCES LIVIDANS XYLAN BINDING DOMAIN CBM13 IN COMPLEX WITH XYLOPENTAOSE 分子名称: ENDO-1,4-BETA-XYLANASE A, GLYCEROL, SULFATE ION, ... 著者 Notenboom, V, Boraston, A.B, Williams, S.J, Kilburn, D.G, Rose, D.R. 登録日 2002-08-06 公開日 2002-09-11 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 High-resolution crystal structures of the lectin-like xylan binding domain from Streptomyces lividans xylanase 10A with bound substrates reveal a novel mode of xylan binding. Biochemistry, 41, 2002
3C8N	Crystal structure of apo-FGD1 from Mycobacterium tuberculosis 分子名称: Probable F420-dependent glucose-6-phosphate dehydrogenase FGD1 著者 Bashiri, G, Squire, C.J, Moreland, N.J, Baker, E.N. 登録日 2008-02-12 公開日 2008-04-22 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of coenzyme and substrate binding. J.Biol.Chem., 283, 2008
4FQD	Crystal structure of the enolpyruvyl transferase NikO from Streptomyces tendae 分子名称: NikO protein, SULFATE ION 著者 Oberdorfer, G, Gruber, K. 登録日 2012-06-25 公開日 2012-07-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural and functional characterization of NikO, an enolpyruvyl transferase essential in nikkomycin biosynthesis. J.Biol.Chem., 287, 2012
3H7Q	Crystal structure of the holo-[Acyl-Carrier-Protein] Synthase (ACPS) from Mycobacterium tuberculosis 分子名称: BICINE, Holo-[acyl-carrier-protein] synthase 著者 Poulsen, C, Wilmanns, M, Song, Y.H. 登録日 2009-04-28 公開日 2010-04-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure of the holo-[Acyl-Carrier-Protein] Synthase (ACPS) from Mycobacterium To be Published
2G85	Crystal structure of chorismate synthase from Mycobacterium tuberculosis at 2.22 angstrons of resolution 分子名称: Chorismate synthase 著者 Dias, M.V.B, dos Santos, B.B, Ely, F, Basso, L.A, Santos, D.S, de Azevedo Jr, W.F. 登録日 2006-03-01 公開日 2007-03-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Crystal structure of chorismate synthase from Mycobacterium tuberculosis at 2.22 angstron of resolution To be Published
2AP9	Crystal structure of acetylglutamate kinase from Mycobacterium tuberculosis CDC1551 分子名称: MAGNESIUM ION, NICKEL (II) ION, acetylglutamate kinase 著者 Rajashankar, K.R, Kniewel, R, Lee, K, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2005-08-15 公開日 2005-08-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of acetylglutamate kinase from Mycobacterium tuberculosis CDC1551 To be Published
1ZAU	Adenylation domain of NAD+ dependent DNA ligase from M.tuberculosis 分子名称: ADENOSINE MONOPHOSPHATE, DNA ligase 著者 Srivastava, S.K, Ramachandran, R. 登録日 2005-04-07 公開日 2005-07-05 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 NAD+-dependent DNA Ligase (Rv3014c) from Mycobacterium tuberculosis: CRYSTAL STRUCTURE OF THE ADENYLATION DOMAIN AND IDENTIFICATION OF NOVEL INHIBITORS J.Biol.Chem., 280, 2005
6WF6	Streptomyces coelicolor methylmalonyl-CoA epimerase 分子名称: COBALT (II) ION, DI(HYDROXYETHYL)ETHER, Methylmalonyl-CoA epimerase 著者 Stunkard, L.M, Benjamin, A.B, Bower, J.B, Huth, T.J, Lohman, J.R. 登録日 2020-04-03 公開日 2020-07-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Substrate Enolate Intermediate and Mimic Captured in the Active Site of Streptomyces coelicolor Methylmalonyl-CoA Epimerase. Chembiochem, 23, 2022
6WFH	Streptomyces coelicolor methylmalonyl-CoA epimerase substrate complex 分子名称: (3S,5R,9R,19E)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,19-tetrahydroxy-8,8,20-trimethyl-10,14-dioxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphahenicos-19-en-21-oic acid 3,5-dioxide (non-preferred name), CHLORIDE ION, COBALT (II) ION, ... 著者 Stunkard, L.M, Benjamin, A.B, Bower, J.B, Huth, T.J, Lohman, J.R. 登録日 2020-04-03 公開日 2020-07-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Substrate Enolate Intermediate and Mimic Captured in the Active Site of Streptomyces coelicolor Methylmalonyl-CoA Epimerase. Chembiochem, 23, 2022
1QFI	SYNTHESIS AND STRUCTURE OF PROLINE RING MODIFIED ACTINOMYCINS OF X TYPE 分子名称: ACTINOMYCIN X2, ETHYL ACETATE, METHANOL 著者 Lifferth, A, Bahner, I, Lackner, H, Schaefer, M. 登録日 1999-04-12 公開日 2003-07-15 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (0.91 Å) 主引用文献 Synthesis and Structure of Proline Ring Modified Actinomycins of the X-Type Z.Naturforsch., 54, 1999
2XB8	Structure of Mycobacterium tuberculosis type II dehydroquinase in complex with inhibitor compound (2R)-2-(4-methoxybenzyl)-3- dehydroquinic acid 分子名称: (1R,2R,4S,5R)-1,4,5-TRIHYDROXY-2-(4-METHOXYBENZYL)-3-OXOCYCLOHEXANECARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-DEHYDROQUINATE DEHYDRATASE, ... 著者 Otero, J.M, Tizon, L, Llamas-Saiz, A.L, Fox, G.C, Gonzalez-Bello, C, van Raaij, M.J. 登録日 2010-04-08 公開日 2010-09-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Understanding the Key Factors that Control the Inhibition of Type II Dehydroquinase by (2R)-2- Benzyl-3-Dehydroquinic Acids. Chemmedchem, 5, 2010
4KV3	Ubiquitin-like domain of the Mycobacterium tuberculosis type VII secretion system protein EccD1 as maltose-binding protein fusion 分子名称: Chimera fusion protein of ESX-1 secretion system protein eccD1 and Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Korotkov, K.V, Evans, T.J. 登録日 2013-05-22 公開日 2014-04-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system. Bmc Struct.Biol., 16, 2016
2CIN	Lysine aminotransferase from M. tuberculosis in the internal aldimine form 分子名称: L-LYSINE-EPSILON AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE 著者 Tripathi, S.M, Ramachandran, R. 登録日 2006-03-24 公開日 2006-08-14 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Direct Evidence for a Glutamate Switch Necessary for Substrate Recognition: Crystal Structures of Lysine Epsilon-Aminotransferase (Rv3290C) from Mycobacterium Tuberculosis H37Rv. J.Mol.Biol., 362, 2006

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