2XB8
Structure of Mycobacterium tuberculosis type II dehydroquinase in complex with inhibitor compound (2R)-2-(4-methoxybenzyl)-3- dehydroquinic acid
Summary for 2XB8
Entry DOI | 10.2210/pdb2xb8/pdb |
Related | 1H05 1H0R 1H0S 2DHQ 2XB9 |
Descriptor | 3-DEHYDROQUINATE DEHYDRATASE, (1R,2R,4S,5R)-1,4,5-TRIHYDROXY-2-(4-METHOXYBENZYL)-3-OXOCYCLOHEXANECARBOXYLIC ACID, SULFATE ION, ... (5 entities in total) |
Functional Keywords | lyase, amino acid biosynthesis |
Biological source | MYCOBACTERIUM TUBERCULOSIS |
Total number of polymer chains | 1 |
Total formula weight | 16781.62 |
Authors | Otero, J.M.,Tizon, L.,Llamas-Saiz, A.L.,Fox, G.C.,Gonzalez-Bello, C.,van Raaij, M.J. (deposition date: 2010-04-08, release date: 2010-09-15, Last modification date: 2023-12-20) |
Primary citation | Peon, A.,Otero, J.M.,Tizon, L.,Prazeres, V.F.V.,Llamas-Saiz, A.L.,Fox, G.C.,van Raaij, M.J.,Lamb, H.,Hawkins, A.R.,Gago, F.,Castedo, L.,Gonzalez-Bello, C. Understanding the Key Factors that Control the Inhibition of Type II Dehydroquinase by (2R)-2- Benzyl-3-Dehydroquinic Acids. Chemmedchem, 5:1726-, 2010 Cited by PubMed: 20815012DOI: 10.1002/CMDC.201000281 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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