3C8N

Crystal structure of apo-FGD1 from Mycobacterium tuberculosis

Summary for 3C8N

Entry DOI	10.2210/pdb3c8n/pdb
Related	3B4Y
Descriptor	Probable F420-dependent glucose-6-phosphate dehydrogenase FGD1 (2 entities in total)
Functional Keywords	tim barrel, non-prolyl cis-peptide, oxidoreductase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	4
Total formula weight	158760.50
Authors	Bashiri, G.,Squire, C.J.,Moreland, N.J.,Baker, E.N. (deposition date: 2008-02-12, release date: 2008-04-22, Last modification date: 2021-10-20)
Primary citation	Bashiri, G.,Squire, C.J.,Moreland, N.J.,Baker, E.N. Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of coenzyme and substrate binding. J.Biol.Chem., 283:17531-17541, 2008 Cited by PubMed: 18434308 DOI: 10.1074/jbc.M801854200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation