3C8N

Crystal structure of apo-FGD1 from Mycobacterium tuberculosis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0005975	biological_process	carbohydrate metabolic process
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0016491	molecular_function	oxidoreductase activity
A	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
A	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A	0045454	biological_process	cell redox homeostasis
A	0052749	molecular_function	glucose-6-phosphate dehydrogenase (coenzyme F420) activity
A	0070967	molecular_function	coenzyme F420 binding
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0005975	biological_process	carbohydrate metabolic process
B	0009274	cellular_component	peptidoglycan-based cell wall
B	0016491	molecular_function	oxidoreductase activity
B	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
B	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
B	0045454	biological_process	cell redox homeostasis
B	0052749	molecular_function	glucose-6-phosphate dehydrogenase (coenzyme F420) activity
B	0070967	molecular_function	coenzyme F420 binding
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0005975	biological_process	carbohydrate metabolic process
C	0009274	cellular_component	peptidoglycan-based cell wall
C	0016491	molecular_function	oxidoreductase activity
C	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
C	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
C	0045454	biological_process	cell redox homeostasis
C	0052749	molecular_function	glucose-6-phosphate dehydrogenase (coenzyme F420) activity
C	0070967	molecular_function	coenzyme F420 binding
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0005975	biological_process	carbohydrate metabolic process
D	0009274	cellular_component	peptidoglycan-based cell wall
D	0016491	molecular_function	oxidoreductase activity
D	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
D	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
D	0045454	biological_process	cell redox homeostasis
D	0052749	molecular_function	glucose-6-phosphate dehydrogenase (coenzyme F420) activity
D	0070967	molecular_function	coenzyme F420 binding

Functional Information from PROSITE/UniProt

site_id	PS00683
Number of Residues	11
Details	RHODANESE_2 Rhodanese C-terminal signature. AtgYEGAWpEF

Chain	Residue	Details
A	ALA115-PHE125

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"18434308","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"18434308","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18434308","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3B4Y","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18434308","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1rhc

Chain	Residue	Details
A	GLU109
A	TRP44
A	HIS40

---

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1rhc

Chain	Residue	Details
B	GLU109
B	HIS40

---

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1rhc

Chain	Residue	Details
C	GLU109
C	TRP44
C	HIS40

---

site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1rhc

Chain	Residue	Details
D	GLU109
D	TRP44
D	HIS40

---