8DOL
 
 | | Mechanism of regulation of the Helicobacter pylori Cagbeta ATPase by CagZ | | 分子名称: | Cag pathogenicity island protein (Cag5), DI(HYDROXYETHYL)ETHER, SULFATE ION | | 著者 | Wu, X, Zhao, Y, Yang, W, Sun, L, Ye, X, Jiang, M, Wang, Q, Wang, Q, Zhang, X, Wu, Y. | | 登録日 | 2022-07-13 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Mechanism of regulation of the Helicobacter pylori Cag beta ATPase by CagZ.
Nat Commun, 14, 2023
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8DWL
 | | Inhibitor-3:PP1 coexpressed complex | | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase PPP1R11, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, ... | | 著者 | Choy, M.S, Srivastava, G, Page, R, Peti, W. | | 登録日 | 2022-08-01 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Inhibitor-3 inhibits Protein Phosphatase 1 via a metal binding dynamic protein-protein interaction.
Nat Commun, 14, 2023
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8DWK
 | | Inhibitor-3:PP1 reconstituted complex | | 分子名称: | E3 ubiquitin-protein ligase PPP1R11, MANGANESE (II) ION, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | | 著者 | Choy, M.S, Srivastava, G, Page, R, Peti, W. | | 登録日 | 2022-08-01 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Inhibitor-3 inhibits Protein Phosphatase 1 via a metal binding dynamic protein-protein interaction.
Nat Commun, 14, 2023
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8E7F
 | | Crystal structure of the autotransporter Ssp from Serratia marcescens. | | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Extracellular serine protease, ... | | 著者 | Hor, L, Pilapitiya, A, Panjikar, S, Paxman, J.J, Heras, B. | | 登録日 | 2022-08-23 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-03-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of a subtilisin-like autotransporter passenger domain reveals insights into its cytotoxic function.
Nat Commun, 14, 2023
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8DSO
 | | Structure of cIAP1, BTK and BCCov | | 分子名称: | (4S)-4-[2-(2-{4-[(2E)-4-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}-4-oxobut-2-en-1-yl]piperazin-1-yl}ethoxy)acetamido]-1-{(2S)-2-cyclohexyl-2-[(N-methyl-L-alanyl)amino]acetyl}-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-L-prolinamide bound form, Baculoviral IAP repeat-containing protein 2, Tyrosine-protein kinase BTK, ... | | 著者 | Schiemer, J.S, Calabrese, M.F. | | 登録日 | 2022-07-22 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.334 Å) | | 主引用文献 | A covalent BTK ternary complex compatible with targeted protein degradation.
Nat Commun, 14, 2023
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6E5W
 | | Crystal structure of human cellular retinol binding protein 3 in complex with abnormal-cannabidiol (abn-CBD) | | 分子名称: | (1'R,2'R)-5'-methyl-6-pentyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydro[1,1'-biphenyl]-2,4-diol, GLYCEROL, Retinol-binding protein 5 | | 著者 | Silvaroli, J.A, Banerjee, S, Kiser, P.D, Golczak, M. | | 登録日 | 2018-07-23 | | 公開日 | 2019-02-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Abnormal Cannabidiol Modulates Vitamin A Metabolism by Acting as a Competitive Inhibitor of CRBP1.
Acs Chem.Biol., 14, 2019
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8EC4
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8DSF
 | | Structure of cIAP1 with BCCov | | 分子名称: | (4S)-4-[2-(2-{4-[(2E)-4-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}-4-oxobut-2-en-1-yl]piperazin-1-yl}ethoxy)acetamido]-1-{(2S)-2-cyclohexyl-2-[(N-methyl-L-alanyl)amino]acetyl}-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-L-prolinamide unbound form, Baculoviral IAP repeat-containing protein 2, ZINC ION | | 著者 | Schiemer, J.S, Calabrese, M.F. | | 登録日 | 2022-07-22 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | A covalent BTK ternary complex compatible with targeted protein degradation.
Nat Commun, 14, 2023
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8EBI
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8ECF
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8EBR
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8DP3
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8E3S
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6E6K
 | | Crystal structure of human cellular retinol-binding protein 4 in complex with abnormal-cannabidiol (abn-CBD) | | 分子名称: | (1'R,2'R)-5'-methyl-6-pentyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydro[1,1'-biphenyl]-2,4-diol, Retinoid-binding protein 7 | | 著者 | Silvaroli, J.A, Banerjee, S, Kiser, P.D, Golczak, M. | | 登録日 | 2018-07-25 | | 公開日 | 2019-02-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Abnormal Cannabidiol Modulates Vitamin A Metabolism by Acting as a Competitive Inhibitor of CRBP1.
Acs Chem.Biol., 14, 2019
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6ELO
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6ELN
 | | Estimation of relative drug-target residence times by random acceleration molecular dynamics simulation | | 分子名称: | 4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol, Heat shock protein HSP 90-alpha, SULFATE ION | | 著者 | Musil, D, Lehmann, M, Eggenweiler, H.-M. | | 登録日 | 2017-09-29 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Estimation of Drug-Target Residence Times by tau-Random Acceleration Molecular Dynamics Simulations.
J Chem Theory Comput, 14, 2018
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8DVI
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8DVF
 | | T4 Bacteriophage primosome with single strand DNA, state 1 | | 分子名称: | DNA (5'-D(P*GP*GP*CP*TP*G)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA primase, ... | | 著者 | Feng, X, Li, H. | | 登録日 | 2022-07-28 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
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4ODP
 | | Structure of SlyD delta-IF from Thermus thermophilus in complex with S2-W23A peptide | | 分子名称: | 30S ribosomal protein S2, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Quistgaard, E.M, Low, C, Nordlund, P. | | 登録日 | 2014-01-10 | | 公開日 | 2015-01-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.747 Å) | | 主引用文献 | Molecular insights into substrate recognition and catalytic mechanism of the chaperone and FKBP peptidyl-prolyl isomerase SlyD.
BMC Biol., 14, 2016
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8E4V
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8DTP
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8DW6
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8E7Q
 | | Crystal Structure of FosB from Bacillus cereus with Zinc and 2-Phosphonopropionic acid | | 分子名称: | (2S)-2-phosphonopropanoic acid, FORMIC ACID, MAGNESIUM ION, ... | | 著者 | Travis, S, Tsodikov, O.V, Garneau-Tsodikova, S, Thompson, M.K. | | 登録日 | 2022-08-24 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Identification and analysis of small molecule inhibitors of FosB from Staphylococcus aureus.
Rsc Med Chem, 14, 2023
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8DUE
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8DUO
 | | DNA-free T4 Bacteriophage gp41 hexamer | | 分子名称: | DnaB-like replicative helicase, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | 著者 | Feng, X, Li, H. | | 登録日 | 2022-07-27 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | | 主引用文献 | Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
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