8DWK
Inhibitor-3:PP1 reconstituted complex
Summary for 8DWK
Entry DOI | 10.2210/pdb8dwk/pdb |
Descriptor | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, E3 ubiquitin-protein ligase PPP1R11, MANGANESE (II) ION, ... (4 entities in total) |
Functional Keywords | inhibitor-3, protein phosphatase 1, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 79278.66 |
Authors | Choy, M.S.,Srivastava, G.,Page, R.,Peti, W. (deposition date: 2022-08-01, release date: 2023-02-15, Last modification date: 2023-10-25) |
Primary citation | Srivastava, G.,Choy, M.S.,Bolik-Coulon, N.,Page, R.,Peti, W. Inhibitor-3 inhibits Protein Phosphatase 1 via a metal binding dynamic protein-protein interaction. Nat Commun, 14:1798-1798, 2023 Cited by PubMed: 37002212DOI: 10.1038/s41467-023-37372-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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