PDB: 46006 件ウェブページステータス検索Chemie searchBIRD

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1R9F	Crystal structure of p19 complexed with 19-bp small interfering RNA 分子名称: 5'-R(*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*AP*UP*U)-3', 5'-R(*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*GP*UP*U)-3', Core protein P19, ... 著者 Ye, K, Malinina, L, Patel, D.J. 登録日 2003-10-28 公開日 2004-01-27 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Recognition of small interfering RNA by a viral suppressor of RNA Nature, 426, 2003
2AEQ	An epidemiologically significant epitope of a 1998 influenza virus neuraminidase forms a highly hydrated interface in the NA-antibody complex. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB heavy chain, FAB light chain, ... 著者 Venkatramani, L, Bochkarev, A, Air, G.M. 登録日 2005-07-23 公開日 2005-12-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 An Epidemiologically Significant Epitope of a 1998 Human Influenza Virus Neuraminidase Forms a Highly Hydrated Interface in the NA-Antibody Complex J.Mol.Biol., 356, 2006
2AFI	Crystal Structure of MgADP bound Av2-Av1 Complex 分子名称: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... 著者 Tezcan, F.A, Kaiser, J.T, Mustafi, D, Walton, M.Y, Howard, J.B, Rees, D.C. 登録日 2005-07-25 公開日 2005-09-06 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Nitrogenase Complexes: Multiple Docking Sites for a Nucleotide Switch Protein Science, 309, 2005
6FO8	Vitamin D nuclear receptor complex 4 分子名称: (1~{R},3~{S},5~{Z})-4-methylidene-5-[(~{E})-3-[3-(6-methyl-6-oxidanyl-heptyl)phenyl]non-2-enylidene]cyclohexane-1,3-diol, Nuclear receptor coactivator 1, Vitamin D3 receptor A 著者 Rochel, N. 登録日 2018-02-06 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Aromatic-Based Design of Highly Active and Noncalcemic Vitamin D Receptor Agonists. J. Med. Chem., 61, 2018
2A64	Crystal Structure of Bacterial Ribonuclease P RNA 分子名称: ribonuclease P RNA 著者 Kazantsev, A.V, Krivenko, A.A, Harrington, D.J, Holbrook, S.R, Adams, P.D, Pace, N.R. 登録日 2005-07-01 公開日 2005-09-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Crystal structure of a bacterial ribonuclease P RNA. Proc.Natl.Acad.Sci.Usa, 102, 2005
7D8X	CryoEM structure of human gamma-secretase in complex with E2012 and L685458 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]piperidin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Yang, G, Zhou, R, Guo, X, Lei, J, Yan, C, Shi, Y. 登録日 2020-10-11 公開日 2021-01-27 最終更新日 2021-02-03 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structural basis of gamma-secretase inhibition and modulation by small molecule drugs. Cell, 184, 2021
1SGI	Crystal structure of the anticoagulant slow form of thrombin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, thrombin 著者 Pineda, A.O, Carrell, C.J, Bush, L.A, Prasad, S, Caccia, S, Chen, Z.W, Mathews, F.S, Di Cera, E. 登録日 2004-02-23 公開日 2004-06-08 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular dissection of na+ binding to thrombin. J.Biol.Chem., 279, 2004
1SI3	Crystal structure of the PAZ domain of human eIF2c1 in complex with a 9-mer siRNA-like duplex 分子名称: 5'-R(*CP*GP*UP*GP*AP*CP*UP*CP*U)-3', Eukaryotic translation initiation factor 2C 1 著者 Ye, K, Ma, J.B, Patel, D. 登録日 2004-02-27 公開日 2004-05-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature, 429, 2004
5AWK	Crystal structure of VDR-LBD/partial agonist complex: 22S-ethyl analogue 分子名称: (1R,3R)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,3S)-3-ethyl-5-oxidanyl-pentan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-2-methylidene-cyclohexane-1,3-diol, Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor,Vitamin D3 receptor 著者 Anami, Y, Itoh, T, Yamamoto, K. 登録日 2015-07-04 公開日 2015-11-18 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Fine tuning of agonistic/antagonistic activity for vitamin D receptor by 22-alkyl chain length of ligands: 22S-Hexyl compound unexpectedly restored agonistic activity. Bioorg.Med.Chem., 23, 2015
1S8D	Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-3A 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... 著者 Martinez-Hackert, E, Anikeeva, N, Kalams, S.A, Walker, B.D, Hendrickson, W.A, Sykulev, Y. 登録日 2004-02-02 公開日 2005-09-06 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes. J.Biol.Chem., 281, 2006
2BL8	1.6 Angstrom crystal structure of EntA-im: a bacterial immunity protein conferring immunity to the antimicrobial activity of the pediocin-like bacteriocin, enterocin A 分子名称: CITRATE ANION, ENTEROCINE A IMMUNITY PROTEIN 著者 Johnsen, L, Dalhus, B, Leiros, I, Nissen-Meyer, J. 登録日 2005-03-02 公開日 2005-03-07 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 1.6-A Crystal Structure of Enta-Im: A Bacterial Immunity Protein Conferring Immunity to the Antimicrobial Activity of the Pediocin-Like Bacteriocin Enterocin A J.Biol.Chem., 280, 2005
1SC8	Urokinase Plasminogen Activator B-Chain-J435 Complex 分子名称: N-(BENZYLSULFONYL)SERYL-N~1~-{4-[AMINO(IMINO)METHYL]BENZYL}GLYCINAMIDE, SULFATE ION, plasminogen activator, ... 著者 Schweinitz, A, Steinmetzer, T, Banke, I.J, Arlt, M.J.E, Stuerzebecher, A, Schuster, O, Geissler, A, Giersiefen, H, Zeslawska, E, Jacob, U, Kruger, A, Stuerzebecher, J. 登録日 2004-02-12 公開日 2004-06-22 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents J.Biol.Chem., 279, 2004
2BTE	Thermus thermophilus Leucyl-tRNA synthetase complexed with a tRNAleu transcript in the post-editing conformation and a post- transfer editing substrate analogue 分子名称: 2'-AMINO-2'-DEOXYADENOSINE, AMINOACYL-TRNA SYNTHETASE, LEUCINE, ... 著者 Cusack, S, Tukalo, M, Yaremchuk, A, Fukunaga, R, Yokoyama, S. 登録日 2005-05-31 公開日 2005-09-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The Crystal Structure of Leucyl-tRNA Synthetase Complexed with tRNA(Leu) in the Post-Transfer- Editing Conformation. Nat.Struct.Mol.Biol., 12, 2005
1RLG	Molecular basis of Box C/D RNA-protein interaction: co-crystal structure of the Archaeal sRNP intiation complex 分子名称: 25-MER, 50S ribosomal protein L7Ae 著者 Moore, T, Zhang, Y, Fenley, M.O, Li, H. 登録日 2003-11-25 公開日 2004-06-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Molecular Basis of Box C/D RNA-Protein Interactions; Cocrystal Structure of Archaeal L7Ae and a Box C/D RNA. STRUCTURE, 12, 2004
1W82	p38 Kinase crystal structure in complex with small molecule inhibitor 分子名称: MITOGEN-ACTIVATED PROTEIN KINASE 14, N-[(3Z)-5-TERT-BUTYL-2-PHENYL-1,2-DIHYDRO-3H-PYRAZOL-3-YLIDENE]-N'-(4-CHLOROPHENYL)UREA 著者 Tickle, J, Jhoti, H, Cleasby, A, Devine, L. 登録日 2004-09-16 公開日 2005-02-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Identification of Novel P38Alpha Map Kinase Inhibitors Using Fragment-Based Lead Generation J.Med.Chem., 48, 2005
7CXI	The ligand-free structure of human PPARgamma LBD F287Y mutant in the presence of the SRC-1 coactivator peptide 分子名称: 16-mer peptide from Nuclear receptor coactivator 1, MALONATE ION, Peroxisome proliferator-activated receptor gamma 著者 Jang, D.M, Han, B.W. 登録日 2020-09-01 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The ligand-free structure of human PPARgamma LBD To Be Published
7CXE	The ligand-free structure of human PPARgamma LBD R280C mutant 分子名称: Peroxisome proliferator-activated receptor gamma 著者 Jang, D.M, Han, B.W. 登録日 2020-09-01 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The ligand-free structure of human PPARgamma LBD To Be Published
7CXK	The ligand-free structure of human PPARgamma LBD R288H mutant in the presence of the SRC-1 coactivator peptide 分子名称: 16-mer peptide from Nuclear receptor coactivator 1, MALONATE ION, Peroxisome proliferator-activated receptor gamma 著者 Jang, D.M, Han, B.W. 登録日 2020-09-01 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The ligand-free structure of human PPARgamma LBD To Be Published
7CXH	The ligand-free structure of human PPARgamma LBD Q286E mutant in the presence of the SRC-1 coactivator peptide 分子名称: 16-mer peptide from Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma 著者 Jang, D.M, Han, B.W. 登録日 2020-09-01 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The ligand-free structure of human PPARgamma LBD To Be Published
7CXF	The ligand-free structure of human PPARgamma LBD C285Y mutant in the presence of the SRC-1 coactivator peptide 分子名称: 16-mer peptide from Nuclear receptor coactivator 1, MALONIC ACID, Peroxisome proliferator-activated receptor gamma 著者 Jang, D.M, Han, B.W. 登録日 2020-09-01 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The ligand-free structure of human PPARgamma LBD To Be Published
7CXJ	The ligand-free structure of human PPARgamma LBD R288C mutant in the presence of the SRC-1 coactivator peptide 分子名称: 16-mer peptide from Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma 著者 Jang, D.M, Han, B.W. 登録日 2020-09-01 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 The ligand-free structure of human PPARgamma LBD To Be Published
7CXL	The ligand-free structure of human PPARgamma LBD S289C mutant in the presence of the SRC-1 coactivator peptide 分子名称: 16-mer peptide from Nuclear receptor coactivator 1, MALONIC ACID, Peroxisome proliferator-activated receptor gamma 著者 Jang, D.M, Han, B.W. 登録日 2020-09-01 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The ligand-free structure of human PPARgamma LBD To Be Published
7CXG	The ligand-free structure of human PPARgamma LBD Q286E mutant 分子名称: GLYCEROL, Peroxisome proliferator-activated receptor gamma 著者 Jang, D.M, Han, B.W. 登録日 2020-09-01 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 The ligand-free structure of human PPARgamma LBD To Be Published
5DSH	Human PPARgamma ligand binding dmain complexed with SB1406 in a covalent bonded form 分子名称: N-[3-(benzyloxy)phenyl]-3-nitrobenzamide, Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma 著者 Jang, J.Y. 登録日 2015-09-17 公開日 2016-09-21 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Human PPARgamma ligand binding dmain complexed with SB1406 in a covalent bonded form To Be Published
6F2L	Crystal structure of the complex between PPARgamma LBD and the ligand LJ570: structure obtained from crystals of the apo-form soaked for 15 days. 分子名称: (2S)-3-(biphenyl-4-yl)-2-(biphenyl-4-yloxy)propanoic acid, Peroxisome proliferator-activated receptor gamma 著者 Pochetti, G, Montanari, M. 登録日 2017-11-24 公開日 2018-01-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Identification of the First PPAR alpha / gamma Dual Agonist Able To Bind to Canonical and Alternative Sites of PPAR gamma and To Inhibit Its Cdk5-Mediated Phosphorylation. J.Med.Chem., 61, 2018

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