PDB: 46006 件ウェブページステータス検索Chemie searchBIRD

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7Y38	Molecular architecture of the chikungunya virus replication complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Protease nsP2, ... 著者 Tan, Y.B, Luo, D. 登録日 2022-06-10 公開日 2022-12-14 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Molecular architecture of the Chikungunya virus replication complex. Sci Adv, 8, 2022
1Q65	CRYSTAL STRUCTURE OF TGT IN COMPLEX WITH 2,6-DIAMINO-8-(2-dimethylaminoethylsulfanylmethyl)-3H-QUINAZOLIN-4-ONE crystallized at pH 5.5 分子名称: 2,6-DIAMINO-8-(2-DIMETHYLAMINOETHYLSULFANYLMETHYL)-3H-QUINAZOLIN-4-ONE, Queuine tRNA-ribosyltransferase, ZINC ION 著者 Brenk, R, Meyer, E, Reuter, K, Stubbs, M.T, Garcia, G.A, Klebe, G. 登録日 2003-08-12 公開日 2004-04-13 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystallographic Study of Inhibitors of tRNA-guanine Transglycosylase Suggests a New Structure-based Pharmacophore for Virtual Screening. J.Mol.Biol., 338, 2004
1PSU	Structure of the E. coli PaaI protein from the phyenylacetic acid degradation operon 分子名称: Phenylacetic acid degradation protein PaaI 著者 Kniewel, R, Buglino, J, Solorzano, V, Wu, J, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2003-06-21 公開日 2003-07-08 最終更新日 2021-02-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure, function, and mechanism of the phenylacetate pathway hot dog-fold thioesterase PaaI. J.Biol.Chem., 281, 2006
1PUI	Structure of EngB GTPase 分子名称: Probable GTP-binding protein engB, SULFATE ION 著者 Kniewel, R, Buglino, J, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2003-06-24 公開日 2003-07-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of an EngB GTPase To be Published
6FGQ	Ligand complex of RORg LBD 分子名称: Nuclear receptor ROR-gamma, methyl 4-[[3-[5-[2-(4-ethylsulfonylphenyl)ethanoylamino]thiophen-3-yl]pyridin-2-yl]oxymethyl]benzoate 著者 Xue, Y, Aagaard, A, Narjes, F. 登録日 2018-01-11 公開日 2018-08-22 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Potent and Orally Bioavailable Inverse Agonists of ROR gamma t Resulting from Structure-Based Design. J. Med. Chem., 61, 2018
1PSQ	Structure of a probable thiol peroxidase from Streptococcus pneumoniae 分子名称: probable thiol peroxidase 著者 Kniewel, R, Buglino, J, Solorzano, V, Wu, J, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2003-06-21 公開日 2003-07-08 最終更新日 2021-02-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of a probable thiol peroxidase from Streptococcus pneumoniae To be Published
2BU1	MS2-RNA HAIRPIN (5BRU -5) COMPLEX 分子名称: 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP *5BU*AP*CP*CP*CP*AP*UP*GP*U)-3', MS2 COAT PROTEIN 著者 Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L. 登録日 2005-06-08 公開日 2005-08-18 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex. Rna, 7, 2001
6FHI	Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 19-mer serine 5 phosphorylated Pol II CTD peptide with a truncated linker. 分子名称: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Lukarska, M, Cusack, S. 登録日 2018-01-14 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Towards New Anti-Influenza Therapeutics: Structure-Activity Relationships in the Interaction between Heterotrimeric Influenza Polymerase and Pol II C-terminal domain To Be Published
1PWZ	Crystal structure of the haloalcohol dehalogenase HheC complexed with (R)-styrene oxide and chloride 分子名称: CHLORIDE ION, R-STYRENE OXIDE, halohydrin dehalogenase 著者 de Jong, R.M, Tiesinga, J.J.W, Rozeboom, H.J, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W. 登録日 2003-07-02 公開日 2003-10-07 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure and Mechanism of a Bacterial Haloalcohol Dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site EMBO J., 22, 2003
6DGP	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with TRAP220 Coactivator Peptide 分子名称: Peroxisome proliferator-activated receptor gamma, TRAP220 Coactivator Peptide (Mediator of RNA polymerase II transcription subunit 1) 著者 Shang, J, Kojetin, D.J. 登録日 2018-05-17 公開日 2019-05-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with TRAP220 Coactivator Peptide To Be Published
1Q63	CRYSTAL STRUCTURE OF TGT IN COMPLEX WITH 2,6-Diamino-8-(1H-imidazol-2-ylsulfanylmethyl)-3H-quinazoline-4-one crystallized at pH 5.5 分子名称: 2,6-DIAMINO-8-(1H-IMIDAZOL-2-YLSULFANYLMETHYL)-3H-QUINAZOLINE-4-ONE, Queuine tRNA-ribosyltransferase, ZINC ION 著者 Brenk, R, Meyer, E, Reuter, K, Stubbs, M.T, Garcia, G.A, Klebe, G. 登録日 2003-08-12 公開日 2004-04-13 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystallographic Study of Inhibitors of tRNA-guanine Transglycosylase Suggests a New Structure-based Pharmacophore for Virtual Screening. J.Mol.Biol., 338, 2004
1ZUX	EosFP Fluorescent Protein- Green Form 分子名称: green to red photoconvertible GPF-like protein EosFP 著者 Nar, H, Nienhaus, K, Wiedenmann, J, Nienhaus, G.U. 登録日 2005-06-01 公開日 2005-06-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural basis for photo-induced protein cleavage and green-to-red conversion of fluorescent protein EosFP. Proc.Natl.Acad.Sci.Usa, 102, 2005
7XWZ	Crystal structure of SARS-CoV-2 N-NTD and dsRNA complex 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Nucleoprotein, ... 著者 Luan, X.D, Li, X.M, Li, Y.F. 登録日 2022-05-27 公開日 2023-02-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein. Sci Bull (Beijing), 67, 2022
1RZN	Crystal Structure of Penicillin-binding protein-related factor A from Bacillus Subtilis. 分子名称: Recombination protein U 著者 Ramagopal, U.A, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2003-12-24 公開日 2004-11-30 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 Crystal Structure of Penicillin-binding protein-related factor A from Bacillus Subtilis. To be Published
1S3N	Structural and Functional Characterization of a Novel Archaeal Phosphodiesterase 分子名称: Hypothetical protein MJ0936, MANGANESE (II) ION 著者 Chen, S, Busso, D, Yakunin, A.F, Kuznetsova, E, Proudfoot, M, Jancrick, J, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) 登録日 2004-01-13 公開日 2004-08-10 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural and functional characterization of a novel phosphodiesterase from Methanococcus jannaschii J.Biol.Chem., 279, 2004
6DGQ	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with CAY10506 分子名称: N-(2-{4-[(2,4-dioxo-3,4-dihydro-2H-1lambda~4~,3-thiazol-5-yl)methyl]phenoxy}ethyl)-5-[(3R)-1,2-dithiolan-3-yl]pentanamide, Peroxisome proliferator-activated receptor gamma 著者 Shang, J, Kojetin, D.J. 登録日 2018-05-17 公開日 2019-05-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Quantitative structural assessment of graded receptor agonism. Proc.Natl.Acad.Sci.USA, 116, 2019
1SDS	Structure of protein L7Ae bound to a K-turn derived from an archaeal box H/ACA sRNA 分子名称: 50S ribosomal protein L7Ae, CALCIUM ION, POTASSIUM ION, ... 著者 Hamma, T, Ferre-D'Amare, A. 登録日 2004-02-13 公開日 2004-05-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of Protein L7Ae Bound to a K-Turn Derived from an Archaeal Box H/ACA sRNA at 1.8 A Resolution. STRUCTURE, 12, 2004
7Y62	Crystal structure of human TFEB HLHLZ domain 分子名称: Transcription factor EB 著者 Yang, G, Li, P, Lin, Y, Liu, Z, Sun, H, Zhao, Z, Fang, P, Wang, J. 登録日 2022-06-18 公開日 2023-03-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB. Proc.Natl.Acad.Sci.USA, 120, 2023
6FZU	RORGT (264-518;C455S) IN COMPLEX WITH THE FRAGMENT ("CPD-1") AND RIP140 PEPTIDE AT 1.80A 分子名称: Nuclear receptor ROR-gamma, Nuclear receptor-interacting protein 1, ~{N}-(3-chloranyl-4-ethoxy-phenyl)ethanamide 著者 Kallen, J. 登録日 2018-03-15 公開日 2018-07-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Optimizing a Weakly Binding Fragment into a Potent ROR gamma t Inverse Agonist with Efficacy in an in Vivo Inflammation Model. J. Med. Chem., 61, 2018
7B92	Structure of a minimal SF3B core in complex with sudemycin D6 (form II) 分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ... 著者 Cretu, C, Pena, V. 登録日 2020-12-14 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12, 2021
1WBO	fragment based p38 inhibitors 分子名称: 2-CHLOROPHENOL, MITOGEN-ACTIVATED PROTEIN KINASE 14 著者 Cleasby, A, Devine, L, Gill, A, Jhoti, H. 登録日 2004-11-04 公開日 2005-01-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Fragment-Based Lead Discovery Using X-Ray Crystallography J.Med.Chem., 48, 2005
7B9C	Structure of a minimal SF3B core in complex with spliceostatin A (form I) 分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ... 著者 Cretu, C, Pena, V. 登録日 2020-12-14 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12, 2021
1WBW	Identification of novel p38 alpha MAP Kinase inhibitors using fragment-based lead generation. 分子名称: 3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE, MITOGEN-ACTIVATED PROTEIN KINASE 14 著者 Tickle, J, Cleasby, A, Devine, L.A, Jhoti, H. 登録日 2004-11-05 公開日 2005-11-03 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Identification of Novel P38Alpha Map Kinase Inhibitors Using Fragment-Based Lead Generation J.Med.Chem., 48, 2005
7BO6	VDR complex with LCA derivative 分子名称: (4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3-(2-methyl-2-oxidanyl-propyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid, Nuclear receptor coactivator 1, Vitamin D3 receptor A 著者 Rochel, N. 登録日 2021-01-24 公開日 2021-08-11 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Lithocholic acid-based design of noncalcemic vitamin D receptor agonists. Bioorg.Chem., 111, 2021
7B91	Structure of a minimal SF3B core in complex with pladienolide D (form I) 分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ... 著者 Cretu, C, Pena, V. 登録日 2020-12-13 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12, 2021

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