PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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2IWV	Structure of the monomeric outer membrane porin OmpG in the open and closed conformation 分子名称: CALCIUM ION, LAURYL DIMETHYLAMINE-N-OXIDE, OUTER MEMBRANE PROTEIN G, ... 著者 Yildiz, O, Vinothkumar, K.R, Goswami, P, Kuehlbrandt, W. 登録日 2006-07-04 公開日 2006-08-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the Monomeric Outer-Membrane Porin Ompg in the Open and Closed Conformation. Embo J., 25, 2006
5L8B	Crystal structure of Rhodospirillum rubrum Rru_A0973 mutant E62A 分子名称: CALCIUM ION, Uncharacterized protein 著者 He, D, Hughes, S, Vanden-Hehir, S, Georgiev, A, Altenbach, K, Tarrant, E, Mackay, C.L, Waldron, K.J, Clarke, D.J, Marles-Wright, J. 登録日 2016-06-07 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structural characterization of encapsulated ferritin provides insight into iron storage in bacterial nanocompartments. Elife, 5, 2016
7SPA	Chlorella virus Hyaluronan Synthase in the GlcNAc-primed, channel-open state 分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... 著者 Maloney, F.P, Kuklewicz, J, Zimmer, J. 登録日 2021-11-02 公開日 2022-04-06 最終更新日 2022-04-20 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structure, substrate recognition and initiation of hyaluronan synthase. Nature, 604, 2022
7E5J	Crystal structure of beta-glucosidase from Thermoanaerobacterium saccharolyticum 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucosidase, SODIUM ION 著者 Nam, K.H. 登録日 2021-02-18 公開日 2022-02-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Biochemical and Structural Analysis of a Glucose-Tolerant beta-Glucosidase from the Hemicellulose-Degrading Thermoanaerobacterium saccharolyticum. Molecules, 27, 2022
5KQF	(4~{S},6~{S})-4-[2,4-bis(fluoranyl)phenyl]-4-methyl-6-pyrimidin-5-yl-5,6-dihydro-1,3-thiazin-2-amine (compound 12) bound to BACE1 分子名称: (4~{S},6~{S})-4-[2,4-bis(fluoranyl)phenyl]-4-methyl-6-pyrimidin-5-yl-5,6-dihydro-1,3-thiazin-2-amine, Beta-secretase 1 著者 Lewis, H.A, Wu, Y.J, Rajamani, R, Thompson, L.A. 登録日 2016-07-06 公開日 2016-09-07 最終更新日 2016-10-05 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Discovery of S3-Truncated, C-6 Heteroaryl Substituted Aminothiazine beta-Site APP Cleaving Enzyme-1 (BACE1) Inhibitors. J.Med.Chem., 59, 2016
7TF4	Cryo-EM structure of SARS-CoV-2 Kappa (B.1.617.1) spike protein (focused refinement of RBD) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Zhu, X, Saville, J.W, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Zhou, S, Tuttle, K.S, Subramaniam, S. 登録日 2022-01-06 公開日 2022-03-30 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants. Nat Commun, 13, 2022
2M1V	NMR solution structure of the d3'-hairpin from the Sc.ai5gamma group II intron including the EBS1:dIBS1 RNA:DNA hybrid 分子名称: DNA_(5'-D(*CP*AP*GP*TP*GP*TP*C)-3')_, RNA (29-MER) 著者 Skilandat, M, Sigel, R.K.O. 登録日 2012-12-07 公開日 2014-06-11 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 The Role of Mg(II) in DNA Cleavage Site Recognition in Group II Intron Ribozymes: SOLUTION STRUCTURE AND METAL ION BINDING SITES OF THE RNADNA COMPLEX. J.Biol.Chem., 289, 2014
7AO1	Crystal structure of CotB2 variant W288F in complex with alendronate 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE, CHLORIDE ION, ... 著者 Dimos, N, Driller, R, Loll, B. 登録日 2020-10-13 公開日 2020-12-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Impression of a Nonexisting Catalytic Effect: The Role of CotB2 in Guiding the Complex Biosynthesis of Cyclooctat-9-en-7-ol. J.Am.Chem.Soc., 142, 2020
7Q5D	Structure of EPCR in a non-canonical conformation 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, Endothelial protein C receptor, ... 著者 Lopez-Sagaseta, J, Erausquin, E. 登録日 2021-11-03 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of EPCR in a non-canonical conformation Biorxiv, 2021
7SP9	Chlorella virus Hyaluronan Synthase in the GlcNAc-primed channel-closed state 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Hyaluronan synthase, ... 著者 Maloney, F.P, Kuklewicz, J, Zimmer, J. 登録日 2021-11-02 公開日 2022-04-06 最終更新日 2022-04-20 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure, substrate recognition and initiation of hyaluronan synthase. Nature, 604, 2022
7SP6	Chlorella virus hyaluronan synthase 分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL HEMISUCCINATE, Hyaluronan synthase, ... 著者 Maloney, F.P, Kuklewicz, J, Zimmer, J. 登録日 2021-11-02 公開日 2022-04-06 最終更新日 2022-04-20 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure, substrate recognition and initiation of hyaluronan synthase. Nature, 604, 2022
7KHV	CpOGA IN COMPLEX WITH LIGAND 54 分子名称: CALCIUM ION, CHLORIDE ION, N-(5-{[6-(5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-2,6-diazaspiro[3.4]octan-2-yl]methyl}-1,3-thiazol-2-yl)acetamide, ... 著者 Shaffer, P.L. 登録日 2020-10-22 公開日 2020-12-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Diazaspirononane Nonsaccharide Inhibitors of O-GlcNAcase (OGA) for the Treatment of Neurodegenerative Disorders. J.Med.Chem., 63, 2020
7E52	Acinetobacter baumannii Thioredoxin reductase 分子名称: Thioredoxin reductase 著者 Park, H.H, Chun, H.L. 登録日 2021-02-16 公開日 2022-02-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Acinetobacter baumannii Thioredoxin reductase To Be Published
5LAC	SeMet Labeled Derivative of Cavally Virus 3CL Protease 分子名称: 3Cl Protease, GLYCEROL 著者 Kanitz, M, Heine, A, Diederich, W.E. 登録日 2016-06-14 公開日 2017-07-12 最終更新日 2019-05-22 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Structural basis for catalysis and substrate specificity of a 3C-like cysteine protease from a mosquito mesonivirus. Virology, 533, 2019
7PJM	Crystal Structure of Ivosidenib-resistant IDH1 variant R132C S280F in complex with NADPH and Ca2+/2-Oxoglutarate 分子名称: 2-OXOGLUTARIC ACID, CALCIUM ION, CHLORIDE ION, ... 著者 Reinbold, R, Rabe, P, Abboud, M.I, Schofield, C.J. 登録日 2021-08-24 公開日 2022-07-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Resistance to the isocitrate dehydrogenase 1 mutant inhibitor ivosidenib can be overcome by alternative dimer-interface binding inhibitors. Nat Commun, 13, 2022
7E3N	Crystal structure of Isocitrate dehydrogenase D252N mutant from Trypanosoma brucei in complexed with NADP+, alpha-ketoglutarate, and ca2+ 分子名称: CALCIUM ION, ISOCITRIC ACID, Isocitrate dehydrogenase [NADP], ... 著者 Arai, N, Shiba, T, Inaoka, D.K, Kita, K, Wang, X, Otani, M, Matsushiro, S, Kojima, C. 登録日 2021-02-09 公開日 2022-02-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of Isocitrate dehydrogenase from Trypanosoma brucei. To Be Published
7KJU	Cgi121-tRNA complex 分子名称: MAGNESIUM ION, RNA (75-MER) 著者 Ceccarelli, D.F, Beenstock, J, Wan, L.C.K, Sicheri, F. 登録日 2020-10-26 公開日 2020-12-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.102 Å) 主引用文献 A substrate binding model for the KEOPS tRNA modifying complex. Nat Commun, 11, 2020
2IV1	SITE DIRECTED MUTAGENESIS OF KEY RESIDUES INVOLVED IN THE CATALYTIC MECHANISM OF CYANASE 分子名称: CHLORIDE ION, CYANATE HYDRATASE, SULFATE ION 著者 Guilloton, M, Walsh, M.A, Joachimiak, A, Anderson, P.M. 登録日 2006-06-08 公開日 2008-10-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 A Twin Set of Low Pka Arginines Ensures the Concerted Acid Base Catalytic Mechanism of Cyanase To be Published
7APX	yeast THO-Sub2 complex 分子名称: ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2,Tho2, ... 著者 Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E. 登録日 2020-10-20 公開日 2020-12-02 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex. Elife, 9, 2020
7SV8	Carbonic Anhydrase IX-mimic Complexed with 3-((2-((Furan-2-ylmethyl)(4-sulfamoylphenethyl)amino)-2-oxoethyl)(phenethyl)amino)propanoic acid 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Carbonic anhydrase 2, N-(2-{[(naphthalen-2-yl)methyl][2-(4-sulfamoylphenyl)ethyl]amino}-2-oxoethyl)-N-(2-phenylethyl)-beta-alanine, ... 著者 Combs, J.E, McKenna, R. 登録日 2021-11-18 公開日 2022-04-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.388 Å) 主引用文献 The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII. J Enzyme Inhib Med Chem, 37, 2022
5KR8	(4~{S},6~{S})-4-[2,4-bis(fluoranyl)phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine (compound 5) bound to BACE1 分子名称: (4~{S},6~{S})-4-[2,4-bis(fluoranyl)phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine, Beta-secretase 1, IODIDE ION 著者 Lewis, H.A, Wu, Y.J, Rajamani, R, Thompson, L.A. 登録日 2016-07-07 公開日 2016-09-07 最終更新日 2016-10-05 実験手法 X-RAY DIFFRACTION (2.118 Å) 主引用文献 Discovery of S3-Truncated, C-6 Heteroaryl Substituted Aminothiazine beta-Site APP Cleaving Enzyme-1 (BACE1) Inhibitors. J.Med.Chem., 59, 2016
7ARV	TwistTower_native-twist 分子名称: SCAFFOLD STRAND, STAPLE STRAND 著者 Kube, M, Kohler, F, Feigl, E, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H. 登録日 2020-10-26 公開日 2020-11-18 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution. Nat Commun, 11, 2020
2J3R	The crystal structure of the bet3-trs31 heterodimer. 分子名称: NITRATE ION, PALMITIC ACID, TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3, ... 著者 Kim, Y.-G, Oh, B.-H. 登録日 2006-08-23 公開日 2006-11-27 最終更新日 2011-10-26 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The Architecture of the Multisubunit Trapp I Complex Suggests a Model for Vesicle Tethering. Cell(Cambridge,Mass.), 127, 2006
7SUW	Carbonic Anhydrase IX-mimic with 2-((3-Aminopropyl)(phenethyl)amino)-N-(furan-2-ylmethyl)-N-(4-sulfamoylphenethyl)acetamide 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Carbonic anhydrase 2, N-(2-{[(furan-2-yl)methyl][2-(4-sulfamoylphenyl)ethyl]amino}-2-oxoethyl)-N-(2-phenylethyl)-beta-alanine, ... 著者 McKenna, R, Combs, J.E. 登録日 2021-11-18 公開日 2022-04-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.456 Å) 主引用文献 The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII. J Enzyme Inhib Med Chem, 37, 2022
5KK3	Atomic Resolution Structure of Monomorphic AB42 Amyloid Fibrils 分子名称: Beta-amyloid protein 42 著者 Colvin, M.T, Silvers, R, Zhe Ni, Q, Can, T.V, Sergeyev, I, Rosay, M, Donovan, K.J, Michael, B, Wall, J, Linse, S, Griffin, R.G. 登録日 2016-06-20 公開日 2016-07-13 最終更新日 2024-05-01 実験手法 SOLID-STATE NMR 主引用文献 Atomic Resolution Structure of Monomorphic A beta 42 Amyloid Fibrils. J.Am.Chem.Soc., 138, 2016

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