7SII
 
 | | Human STING bound to both cGAMP and 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide (Compound 53) | | 分子名称: | 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide, Stimulator of interferon genes protein, cGAMP | | 著者 | Lu, D, Shang, G, Jie, L, Lu, Y, Bai, X.C, Zhang, X. | | 登録日 | 2021-10-14 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Activation of STING by targeting a pocket in the transmembrane domain.
Nature, 604, 2022
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7LO2
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8CTJ
 | | Cryo-EM structure of TMEM87A | | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Transmembrane protein 87A | | 著者 | Hoel, C.M, Zhang, L, Brohawn, S.G. | | 登録日 | 2022-05-15 | | 公開日 | 2022-07-20 | | 最終更新日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (4.74 Å) | | 主引用文献 | Structure of the GOLD-domain seven-transmembrane helix protein family member TMEM87A.
Elife, 11, 2022
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8P4B
 | | Structural insights into human co-transcriptional capping - structure 2 | | 分子名称: | DNA (35-MER), DNA (5'-D(P*AP*GP*CP*GP*GP*CP*GP*GP*AP*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*AP*GP*CP*TP*G)-3'), DNA-directed RNA polymerase II subunit E, ... | | 著者 | Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. | | 登録日 | 2023-05-20 | | 公開日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into human co-transcriptional capping.
Mol.Cell, 83, 2023
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8DCD
 | | RNA ligase RtcB from Pyrococcus horikoshii in complex with Zn2+ and GTP | | 分子名称: | CHLORIDE ION, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Jacewicz, A, Dantuluri, S, Shuman, S. | | 登録日 | 2022-06-16 | | 公開日 | 2022-10-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Structures of RNA ligase RtcB in complexes with divalent cations and GTP.
Rna, 28, 2022
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7S16
 | | Crystal structure of alpha-COP-WD40 domain R57A mutant | | 分子名称: | Coatomer subunit alpha, SODIUM ION | | 著者 | Dey, D, Singh, S, Khan, S, Martin, M, Schnicker, N, Gakhar, L, Pierce, B, Hasan, S.S. | | 登録日 | 2021-09-01 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking
Commun Biol, 5, 2022
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7S22
 | | Crystal structure of alpha-COP-WD40 domain | | 分子名称: | Coatomer subunit alpha | | 著者 | Dey, D, Singh, S, Khan, S, Martin, M, Schnicker, N, Gakhar, L, Pierce, B, Hasan, S.S. | | 登録日 | 2021-09-02 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking
Commun Biol, 5, 2022
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7SC1
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7S23
 | | Crystal structure of alpha-COP-WD40 domain, Y139A mutant | | 分子名称: | Coatomer subunit alpha | | 著者 | Dey, D, Singh, S, Khan, S, Martin, M, Schnicker, N, Gakhar, L, Pierce, B, Hasan, S.S. | | 登録日 | 2021-09-03 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking
Commun Biol, 5, 2022
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8DC9
 | | RNA ligase RtcB from Pyrococcus horikoshii in complex with Mn2+ and GTP | | 分子名称: | CHLORIDE ION, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... | | 著者 | Jacewicz, A, Dantuluri, S, Shuman, S. | | 登録日 | 2022-06-16 | | 公開日 | 2022-10-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Structures of RNA ligase RtcB in complexes with divalent cations and GTP.
Rna, 28, 2022
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6US9
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8DFH
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7SEM
 | | Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ... | | 著者 | Rush, S.A, Hsieh, C.-L, McLellan, J.S. | | 登録日 | 2021-09-30 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins.
Nat Commun, 13, 2022
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7LIX
 | | CaRSP1 and scaffolded phycoerythrin beta subunits from the phycobilisome of Porphyridium purpureum | | 分子名称: | B-phycoerythrin beta chain, CaRSP1, PHYCOERYTHROBILIN | | 著者 | Rathbone, H.W, Landsberg, M.J, Michie, K.A, Green, B.R, Curmi, P.M.G. | | 登録日 | 2021-01-28 | | 公開日 | 2021-04-07 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Scaffolding proteins guide the evolution of algal light harvesting antennas.
Nat Commun, 12, 2021
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7AYC
 | | Crystal Structure of human mitochondrial 2-Enoyl Thioester Reductase (MECR) with single mutation G165Q | | 分子名称: | CHLORIDE ION, Enoyl-[acyl-carrier-protein] reductase, mitochondrial | | 著者 | Rahman, M.T, Koski, M.K, Autio, K.J, Kastaniotis, A.J, Wierenga, R.K, Hiltunen, J.K. | | 登録日 | 2020-11-12 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | An engineered variant of MECR reductase reveals indispensability of long-chain acyl-ACPs for mitochondrial respiration.
Nat Commun, 14, 2023
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7LR7
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7LR2
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7LSE
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8DC6
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8OGG
 | | Crystal structure of FutA after an accumulated dose of 5 kGy | | 分子名称: | FE (III) ION, Putative iron ABC transporter, substrate binding protein | | 著者 | Bolton, R, Tews, I. | | 登録日 | 2023-03-20 | | 公開日 | 2023-08-30 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | A redox switch allows binding of Fe(II) and Fe(III) ions in the cyanobacterial iron-binding protein FutA from Prochlorococcus.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8ONL
 | | Crystal structure of D-amino acid aminotransferase from Aminobacterium colombiense point mutant E113A | | 分子名称: | Aminotransferase class IV, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Matyuta, I.O, Boyko, K.M, Minyaev, M.E, Shilova, S.A, Bezsudnova, E.Y, Popov, V.O. | | 登録日 | 2023-04-03 | | 公開日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | In search for structural targets for engineering d-amino acid transaminase: modulation of pH optimum and substrate specificity.
Biochem.J., 480, 2023
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7SE6
 | | Crystal structure of human Fibrillarin in ligand-free state | | 分子名称: | FORMIC ACID, rRNA 2'-O-methyltransferase fibrillarin | | 著者 | Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T. | | 登録日 | 2021-09-30 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin.
Pharmaceuticals, 15, 2021
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7LSF
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8DC4
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7LQX
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