PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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7B4Z	Synthetic DNA duplex dodecamer 分子名称: DNA (5'-D(*CP*AP*CP*GP*CP*CP*GP*CP*TP*G)-3'), DNA (5'-D(*CP*AP*GP*CP*GP*GP*CP*GP*TP*G)-3') 著者 Lomzov, A.A, Shernuykov, A.V, Sviridov, E.A, Shevelev, G.Y, Bagryanskaya, E.G, Pyshnyi, D.V. 登録日 2020-12-03 公開日 2020-12-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Study of a DNA Duplex by Nuclear Magnetic Resonance and Molecular Dynamics Simulations. Validation of Pulsed Dipolar Electron Paramagnetic Resonance Distance Measurements Using Triarylmethyl-Based Spin Labels. J Phys Chem B, 120, 2016
2MIY	Solution NMR structure of a preQ1 Class II riboswitch from Streptococcus pneumoniae 分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, RNA_(59-MER) 著者 Kang, M, Eichhorn, C.D, Feigon, J. 登録日 2013-12-20 公開日 2014-01-29 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural determinants for ligand capture by a class II preQ1 riboswitch. Proc.Natl.Acad.Sci.USA, 111, 2014
7AMD	In situ assembly of choline acetyltransferase ligands by a hydrothiolation reaction reveals key determinants for inhibitor design 分子名称: Choline O-acetyltransferase, SODIUM ION, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{R})-2,2-dimethyl-4-[[3-[2-[(1~{R})-2-(1-methylpyridin-4-yl)-1-naphthalen-1-yl-ethyl]sulfanylethylamino]-3-oxidanylidene-propyl]amino]-3-oxidanyl-4-oxidanylidene-butyl] hydrogen phosphate 著者 Allgardsson, A, Ekstrom, F.J, Wiktelius, D, Bergstrom, T, Hoster, N, Akfur, C, Forsgren, N, Lejon, C, Hedenstrom, M, Linusson, A. 登録日 2020-10-08 公開日 2020-10-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 In Situ Assembly of Choline Acetyltransferase Ligands by a Hydrothiolation Reaction Reveals Key Determinants for Inhibitor Design. Angew.Chem.Int.Ed.Engl., 60, 2021
7PFZ	Crystal Structure of Unlinked NS2B-NS3 Protease from Zika Virus in Complex with Inhibitor MI-2267 分子名称: Inhibitor MI-2267, Serine protease NS3, Serine protease subunit NS2B 著者 Huber, S, Heine, A, Steinmetzer, T. 登録日 2021-08-12 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structure-Based Optimization and Characterization of Macrocyclic Zika Virus NS2B-NS3 Protease Inhibitors. J.Med.Chem., 65, 2022
7E3U	Crystal structure of the Pseudomonas aeruginosa dihydropyrimidinase complexed with 5-AU 分子名称: 5-AMINO-1H-PYRIMIDINE-2,4-DIONE, D-hydantoinase/dihydropyrimidinase, ZINC ION 著者 Yang, Y.C, Luo, R.H, Huang, Y.H, Huang, C.Y, Lin, E.S. 登録日 2021-02-09 公開日 2022-02-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.159 Å) 主引用文献 Molecular Insights into How the Dimetal Center in Dihydropyrimidinase Can Bind the Thymine Antagonist 5-Aminouracil: A Different Binding Mode from the Anticancer Drug 5-Fluorouracil. Bioinorg Chem Appl, 2022, 2022
7PQ1	Ligand-free crystal structure of a staphylococcal orthologue of CYP134A1 分子名称: Cytochrome P450 protein, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE 著者 Snee, M, Levy, C, Leys, D, Katariya, M, Munro, A.W. 登録日 2021-09-15 公開日 2022-09-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Crystal structure of a staphylococcal orthologue of CYP134A1 (CYPX) in complex with Cyclo-L-leucyl-L-leucine To Be Published
7KNI	Cryo-EM structure of Triple ACE2-bound SARS-CoV-2 Trimer Spike at pH 5.5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... 著者 Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L. 登録日 2020-11-04 公開日 2020-12-16 最終更新日 2021-12-15 実験手法 ELECTRON MICROSCOPY (3.91 Å) 主引用文献 Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains. Cell Host Microbe, 28, 2020
2IRM	Crystal structure of mitogen-activated protein kinase kinase kinase 7 interacting protein 1 from Anopheles gambiae 分子名称: mitogen-activated protein kinase kinase kinase 7 interacting protein 1 著者 Jin, X, Bonanno, J.B, Pelletier, L, Freeman, J.C, Wasserman, S, Sauder, J.M, Burley, S.K, Shapiro, L, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2006-10-15 公開日 2006-11-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural genomics of protein phosphatases. J.STRUCT.FUNCT.GENOM., 8, 2007
2MEJ	Solution Structure of the Complex Between BCL-xL and the p53 Core Domain determined with PRE restraints 分子名称: Bcl-2-like protein 1, Cellular tumor antigen p53, ZINC ION 著者 Viacava Follis, A, Grace, C.R, Kriwacki, R.W. 登録日 2013-09-25 公開日 2014-04-30 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The DNA-binding domain mediates both nuclear and cytosolic functions of p53. Nat.Struct.Mol.Biol., 21, 2014
7TF1	Cryo-EM structure of SARS-CoV-2 Kappa (B.1.617.1) Q484I spike protein (focused refinement of RBD) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Zhu, X, Saville, J.W, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Zhou, S, Tuttle, K.S, Subramaniam, S. 登録日 2022-01-06 公開日 2022-03-30 実験手法 ELECTRON MICROSCOPY (3.57 Å) 主引用文献 Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants. Nat Commun, 13, 2022
7L0X	Human Bocavirus 2 (pH 2.6) 分子名称: VP2 著者 Luo, M, Mietzsch, M, Agbandje-McKenna, M. 登録日 2020-12-13 公開日 2021-01-27 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.51 Å) 主引用文献 pH-Induced Conformational Changes of Human Bocavirus Capsids. J.Virol., 95, 2021
7STK	Full-length insulin receptor bound with unsaturated insulin WT (2 insulins bound) asymmetric conformation (Conformation 2) 分子名称: Insulin, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-11-14 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
2MNX	Major groove orientation of the (2S)-N6-(2-hydroxy-3-buten-1-yl)-2'-deoxyadenosine DNA adduct induced by 1,2-epoxy-3-butene 分子名称: 5'-D(*CP*GP*GP*AP*CP*(6HB)P*AP*GP*AP*AP*G)-3', 5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3' 著者 Kowal, E.A, Kotapati, S, Turo, M, Tretyakova, N, Stone, M.P. 登録日 2014-04-16 公開日 2014-10-08 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Major Groove Orientation of the (2S)-N(6)-(2-Hydroxy-3-buten-1-yl)-2'-deoxyadenosine DNA Adduct Induced by 1,2-Epoxy-3-butene. Chem.Res.Toxicol., 27, 2014
7AGL	crystal structure of the apo form of the N-acetylmuramyl-L-alanine amidase, Ami1, from Mycobacterium abscessus. 分子名称: N-acetylmuramoyl-L-alanine amidase, ZINC ION 著者 Blaise, M. 登録日 2020-09-23 公開日 2020-11-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Functional Characterization of the N -Acetylmuramyl-l-Alanine Amidase, Ami1, from Mycobacterium abscessus . Cells, 9, 2020
7STH	Full-length insulin receptor bound with unsaturated insulin WT (2 insulin bound) symmetric conformation 分子名称: Insulin, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-11-13 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
3A1M	A fusion protein of a beta helix region of gene product 5 and the foldon region of bacteriophage T4 分子名称: POTASSIUM ION, chimera of thrombin cleavage site, Tail-associated lysozyme, ... 著者 Yokoi, N, Suzuki, A, Hikage, T, Koshiyama, T, Terauchi, M, Yutani, K, Kanamaru, S, Arisaka, F, Yamane, T, Watanabe, Y, Ueno, T. 登録日 2009-04-11 公開日 2010-04-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Construction of Robust Bio-nanotubes using the Controlled Self-Assembly of Component Proteins of Bacteriophage T4 Small, 6, 2010
7POQ	Crystal structure of profragilysin-3 (proBFT-3) from Bacteroides fragilis in complex with foliosidine in P41212. 分子名称: 1,2-ETHANEDIOL, BFT-3, CHLORIDE ION, ... 著者 Eckhard, U, Guevara, T, Gomis-Ruth, F.X. 登録日 2021-09-09 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Repositioning small molecule drugs as allosteric inhibitors of the BFT-3 toxin from enterotoxigenic Bacteroides fragilis. Protein Sci., 31, 2022
7T6U	Structure of the human FPR2-Gi complex with CGEN-855A 分子名称: B9-scFv, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Zhuang, Y.W. 登録日 2021-12-14 公開日 2022-03-30 最終更新日 2022-10-19 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2. Nat Commun, 13, 2022
5KNB	Crystal structure of the 2 ADP-bound V1 complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... 著者 Suzuki, K, Mizutani, K, Maruyama, S, Shimono, K, Imai, F.L, Muneyuki, E, Kakinuma, Y, Ishizuka-Katsura, Y, Shirouzu, M, Yokoyama, S, Yamato, I, Murata, T. 登録日 2016-06-28 公開日 2016-11-02 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.251 Å) 主引用文献 Crystal structures of the ATP-binding and ADP-release dwells of the V1 rotary motor Nat Commun, 7, 2016
7TF5	Cryo-EM structure of SARS-CoV-2 Kappa (B.1.617.1) spike protein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Zhu, X, Saville, J.W, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Zhou, S, Tuttle, K.S, Subramaniam, S. 登録日 2022-01-06 公開日 2022-03-30 実験手法 ELECTRON MICROSCOPY (3.16 Å) 主引用文献 Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants. Nat Commun, 13, 2022
7AID	HIV-1 REVERSE TRANSCRIPTASE COMPLEX WITH DNA AND D-ASPARTATE TENOFOVIR 分子名称: D-Aspartate Tenofovir, DNA (5'-D(*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(DDG))-3'), DNA (5'-D(P*GP*GP*TP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*G)-3'), ... 著者 Gu, W, Martinez, S.E, Nguyen, H, Xu, H, Herdewijn, P, de Jonghe, S, Das, K. 登録日 2020-09-26 公開日 2021-01-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Tenofovir-Amino Acid Conjugates Act as Polymerase Substrates-Implications for Avoiding Cellular Phosphorylation in the Discovery of Nucleotide Analogues. J.Med.Chem., 64, 2021
7T7T	Structure of TSK/BRU1 bound to histone H3.1 分子名称: Histone H3.1, Protein TONSOKU 著者 Davarinejad, H, Couture, J.F. 登録日 2021-12-15 公開日 2022-03-30 実験手法 X-RAY DIFFRACTION (3.17 Å) 主引用文献 The histone H3.1 variant regulates TONSOKU-mediated DNA repair during replication. Science, 375, 2022
3ICE	Rho transcription termination factor bound to RNA and ADP-BeF3 分子名称: 5'-R(P*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... 著者 Thomsen, N.D, Berger, J.M. 登録日 2009-07-17 公開日 2009-11-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Running in reverse: the structural basis for translocation polarity in hexameric helicases. Cell(Cambridge,Mass.), 139, 2009
7L0Y	Human Bocavirus 1 (pH 2.6) 分子名称: VP2 著者 Luo, M, Mietzsch, M, Agbandje-McKenna, M. 登録日 2020-12-13 公開日 2021-01-27 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.54 Å) 主引用文献 pH-Induced Conformational Changes of Human Bocavirus Capsids. J.Virol., 95, 2021
7E4X	Structure of Enolase from Mycobacterium tuberculosis 分子名称: Enolase 著者 Bose, S, Vinothkumar, K.R. 登録日 2021-02-15 公開日 2022-02-16 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (3.08 Å) 主引用文献 Structural snapshots of Mycobacterium tuberculosis enolase reveal dual mode of 2PG binding and its implication in enzyme catalysis. Iucrj, 10, 2023

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