6HKI
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3CXK
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![BU of 3cxk by Molmil](/molmil-images/mine/3cxk) | 1.7 A Crystal structure of methionine-R-sulfoxide reductase from Burkholderia pseudomallei: crystallization in a microfluidic crystal card. | 分子名称: | ACETATE ION, Methionine-R-sulfoxide reductase, ZINC ION | 著者 | Lovell, S, Gerdts, C, Staker, B, Craigen, D, Stewart, L, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2008-04-24 | 公開日 | 2008-05-27 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The plug-based nanovolume Microcapillary Protein Crystallization System (MPCS). Acta Crystallogr.,Sect.D, 64, 2008
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7PRT
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![BU of 7prt by Molmil](/molmil-images/mine/7prt) | Crystal structure of human heparanase in complex with covalent inhibitor CB678 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-alpha-D-arabino-hexopyranose-(1-4)-(2R,3S,5R,6R)-2,3,4,5,6-pentakis(oxidanyl)cyclohexane-1-carboxylic acid, ... | 著者 | Wu, L, Armstrong, Z, Davies, G.J. | 登録日 | 2021-09-22 | 公開日 | 2022-08-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo. Proc.Natl.Acad.Sci.USA, 119, 2022
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4QX6
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![BU of 4qx6 by Molmil](/molmil-images/mine/4qx6) | CRYSTAL STRUCTURE OF GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM STREPTOCOCCUS AGALACTIAE NEM316 at 2.46 ANGSTROM RESOLUTION | 分子名称: | 1,2-ETHANEDIOL, Glyceraldehyde 3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Ayres, C.A, Schormann, N, Banerjee, S, Chattopadhyay, D. | 登録日 | 2014-07-18 | 公開日 | 2014-10-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Structure of Streptococcus agalactiae glyceraldehyde-3-phosphate dehydrogenase holoenzyme reveals a novel surface. Acta Crystallogr F Struct Biol Commun, 70, 2014
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3CYF
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![BU of 3cyf by Molmil](/molmil-images/mine/3cyf) | Crystal Structure of E18N DJ-1 | 分子名称: | Protein DJ-1 | 著者 | Witt, A.C, Lakshminarasimhan, M, Remington, B.C, Hasim, S, Pozharski, E, Wilson, M.A. | 登録日 | 2008-04-25 | 公開日 | 2008-07-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Cysteine pKa depression by a protonated glutamic acid in human DJ-1. Biochemistry, 47, 2008
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7PSK
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![BU of 7psk by Molmil](/molmil-images/mine/7psk) | Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with covalent inhibitor GR109 | 分子名称: | 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-(2R,3S,5R,6R)-2,3,4,5,6-pentakis(oxidanyl)cyclohexane-1-carboxylic acid, Beta-glucuronidase | 著者 | Armstrong, Z, Wu, L, Davies, G.J. | 登録日 | 2021-09-23 | 公開日 | 2022-08-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo. Proc.Natl.Acad.Sci.USA, 119, 2022
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6HND
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![BU of 6hnd by Molmil](/molmil-images/mine/6hnd) | Crystal structure of the aromatic aminotransferase Aro9 from C. Albicans | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Aromatic-amino-acid:2-oxoglutarate transaminase, POTASSIUM ION, ... | 著者 | Kiliszek, A, Rzad, K, Rypniewski, W, Milewski, S, Gabriel, I. | 登録日 | 2018-09-14 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties. J.Struct.Biol., 205, 2019
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3CZ9
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![BU of 3cz9 by Molmil](/molmil-images/mine/3cz9) | Crystal Structure of E18L DJ-1 | 分子名称: | O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, Protein DJ-1 | 著者 | Witt, A.C, Lakshminarasimhan, M, Remington, B.C, Hasim, S, Pozharski, E, Wilson, M.A. | 登録日 | 2008-04-28 | 公開日 | 2008-07-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Cysteine pKa depression by a protonated glutamic acid in human DJ-1. Biochemistry, 47, 2008
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4KOA
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![BU of 4koa by Molmil](/molmil-images/mine/4koa) | Crystal Structure Analysis of 1,5-anhydro-D-fructose reductase from Sinorhizobium meliloti | 分子名称: | 1,5-anhydro-D-fructose reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Schu, M, Faust, A, Stosik, B, Kohring, G.-W, Giffhorn, F, Scheidig, A.J. | 登録日 | 2013-05-11 | 公開日 | 2013-08-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | The structure of substrate-free 1,5-anhydro-D-fructose reductase from Sinorhizobium meliloti 1021 reveals an open enzyme conformation. Acta Crystallogr.,Sect.F, 69, 2013
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6HU5
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6HNV
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![BU of 6hnv by Molmil](/molmil-images/mine/6hnv) | Crystal structure of aminotransferase Aro9 from C. Albicans with ligands | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINOHEXANEDIOIC ACID, 2-OXOADIPIC ACID, ... | 著者 | Kiliszek, A, Rzad, K, Rypniewski, W, Milewski, S, Gabriel, I. | 登録日 | 2018-09-17 | 公開日 | 2019-02-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties. J.Struct.Biol., 205, 2019
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6BH7
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![BU of 6bh7 by Molmil](/molmil-images/mine/6bh7) | Phosphotriesterase variant R18+254S | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase, ... | 著者 | Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. | 登録日 | 2017-10-30 | 公開日 | 2019-01-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Phosphotriesterase variant R18+254S To Be Published
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5WW6
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7PSI
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![BU of 7psi by Molmil](/molmil-images/mine/7psi) | Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with covalent inhibitor ME727 | 分子名称: | (2R,3S,5R,6R)-2,3,4,5,6-pentakis(oxidanyl)cyclohexane-1-carboxylic acid, Beta-glucuronidase, SULFATE ION | 著者 | Armstrong, Z, Wu, L, Davies, G.J. | 登録日 | 2021-09-23 | 公開日 | 2022-08-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo. Proc.Natl.Acad.Sci.USA, 119, 2022
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4QYH
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![BU of 4qyh by Molmil](/molmil-images/mine/4qyh) | CHK1 kinase domain in complex with diazacarbazole GNE-783 | 分子名称: | 3-[4-(4-methylpiperazin-1-yl)phenyl]-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile, Serine/threonine-protein kinase Chk1 | 著者 | Wiesmann, C, Wu, P. | 登録日 | 2014-07-24 | 公開日 | 2014-12-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of the 1,7-diazacarbazole class of inhibitors of checkpoint kinase 1. Bioorg.Med.Chem.Lett., 24, 2014
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7PSH
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7PSJ
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![BU of 7psj by Molmil](/molmil-images/mine/7psj) | Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with covalent inhibitor VL166 | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-(2R,3S,5R,6R)-2,3,4,5,6-pentakis(oxidanyl)cyclohexane-1-carboxylic acid, Beta-glucuronidase | 著者 | Armstrong, Z, Wu, L, Davies, G.J. | 登録日 | 2021-09-23 | 公開日 | 2022-08-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo. Proc.Natl.Acad.Sci.USA, 119, 2022
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4R1S
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![BU of 4r1s by Molmil](/molmil-images/mine/4r1s) | Crystal structure of Petunia hydrida cinnamoyl-CoA reductase | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, cinnamoyl CoA reductase | 著者 | Noel, J.P, Louie, G.V, Bowman, M.E, Bomati, E.K. | 登録日 | 2014-08-07 | 公開日 | 2014-10-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis. Plant Cell, 26, 2014
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2GDY
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![BU of 2gdy by Molmil](/molmil-images/mine/2gdy) | Solution structure of the B. brevis TycC3-PCP in A-state | 分子名称: | Tyrocidine synthetase III | 著者 | Koglin, A, Loehr, F, Rogov, V.V, Marahiel, M.A, Bernhard, F, Doetsch, V. | 登録日 | 2006-03-17 | 公開日 | 2006-08-01 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformational switches modulate protein interactions in peptide antibiotic synthetases Science, 312, 2006
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5WW5
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6HQD
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6FUF
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![BU of 6fuf by Molmil](/molmil-images/mine/6fuf) | Crystal structure of the rhodopsin-mini-Go complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(o) subunit alpha, RETINAL, ... | 著者 | Tsai, C.-J, Weinert, T, Muehle, J, Pamula, F, Nehme, R, Flock, T, Nogly, P, Edwards, P.C, Carpenter, B, Gruhl, T, Ma, P, Deupi, X, Standfuss, J, Tate, C.G, Schertler, G.F.X. | 登録日 | 2018-02-27 | 公開日 | 2018-10-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.117 Å) | 主引用文献 | Crystal structure of rhodopsin in complex with a mini-Gosheds light on the principles of G protein selectivity. Sci Adv, 4, 2018
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6GBX
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![BU of 6gbx by Molmil](/molmil-images/mine/6gbx) | Crystal structure of human glutaminyl cyclase variant Y115E-Y117E in complex with SEN177 | 分子名称: | 1,2-ETHANEDIOL, 2-fluoranyl-5-[2-[4-(4-methyl-1,2,4-triazol-3-yl)piperidin-1-yl]pyridin-3-yl]pyridine, Glutaminyl-peptide cyclotransferase, ... | 著者 | Pozzi, C, Di Pisa, F, Benvenuti, M, Mangani, S. | 登録日 | 2018-04-16 | 公開日 | 2018-09-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | The structure of the human glutaminyl cyclase-SEN177 complex indicates routes for developing new potent inhibitors as possible agents for the treatment of neurological disorders. J. Biol. Inorg. Chem., 23, 2018
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7WGR
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![BU of 7wgr by Molmil](/molmil-images/mine/7wgr) | Cryo-electron microscopic structure of the 2-oxoglutarate dehydrogenase (E1) component of the human alpha-ketoglutarate (2-oxoglutarate) dehydrogenase complex | 分子名称: | 2-oxoglutarate dehydrogenase, mitochondrial, CALCIUM ION, ... | 著者 | Yu, X, Yang, W, Zhong, Y.H, Ma, X.M, Gao, Y.Z. | 登録日 | 2021-12-28 | 公開日 | 2022-06-01 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Structural basis for the activity and regulation of human alpha-ketoglutarate dehydrogenase revealed by Cryo-EM Biochem.Biophys.Res.Commun., 602, 2022
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2UZ9
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![BU of 2uz9 by Molmil](/molmil-images/mine/2uz9) | Human guanine deaminase (guaD) in complex with zinc and its product Xanthine. | 分子名称: | GUANINE DEAMINASE, XANTHINE, ZINC ION | 著者 | Moche, M, Welin, M, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, van den berg, S, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC) | 登録日 | 2007-04-26 | 公開日 | 2007-05-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Human Guanine Deaminase (Guad) in Complex with Zinc and its Product Xhantine To be Published
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