7BSJ

Crystal structure of human ME2 R484W

Summary for 7BSJ

• Entry DOI: 10.2210/pdb7bsj/pdb
• Descriptor: NAD-dependent malic enzyme, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: malate dehydrogenase, nad-dependent malic enzyme, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 130240.54

Authors

Chen, W.L.,Tai, S.C.,Hung, H.C.,Ho, M.C. (deposition date: 2020-03-30, release date: 2021-02-10, Last modification date: 2023-11-29)

• Primary citation: Hsieh, J.Y.,Yang, H.P.,Tewary, S.K.,Cheng, H.C.,Liu, Y.L.,Tai, S.C.,Chen, W.L.,Hsu, C.H.,Huang, T.J.,Chou, C.J.,Huang, Y.N.,Peng, C.T.,Ho, M.C.,Liu, G.Y.,Hung, H.C.; Single nucleotide variants lead to dysregulation of the human mitochondrial NAD(P) + -dependent malic enzyme.; Iscience, 24:102034-102034, 2021; PubMed: 33554057; DOI: 10.1016/j.isci.2021.102034

Experimental method

X-RAY DIFFRACTION (2.48 Å)