7BSJ
Crystal structure of human ME2 R484W
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NAD-dependent malic enzyme, mitochondrial | polymer | 566 | 63535.0 | 2 | UniProt (P23368) Pfam (PF00390) Pfam (PF03949) | Homo sapiens (Human) | NAD-ME,Malic enzyme 2 |
| 2 | C, E, H, J (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | D, I (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | F, K (A, B) | FUMARIC ACID | non-polymer | 116.1 | 2 | Chemie (FUM) | |||
| 5 | G, L (A, B) | TARTRONATE | non-polymer | 118.0 | 2 | Chemie (TTN) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
A, B: 20 - 584 (UniProt: P23368)
| PDB | External Database | Details |
|---|---|---|
| Met 19 | - | initiating methionine |
| Trp 484 | Arg 484 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 127070.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 3170.5 | |
| All* | Total formula weight | 130240.5 |
