PDB: 30867 件ウェブページステータス検索Chemie searchBIRD

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5T3A	Maedi-Visna virus (MVV) integrase CCD-CTD (residues 60-275) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, integrase 著者 Cook, N.J, Pye, V.E, Cherepanov, P. 登録日 2016-08-25 公開日 2017-01-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 A supramolecular assembly mediates lentiviral DNA integration. Science, 355, 2017
5T44	Crystal structure of Frizzled 7 CRD 分子名称: Frizzled-7 著者 Mukund, S, Nile, A.H, Stanger, K, Hannous, R.H, Wang, W. 登録日 2016-08-29 公開日 2017-04-05 最終更新日 2017-05-03 実験手法 X-RAY DIFFRACTION (1.9944 Å) 主引用文献 Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5SY6	Atomic resolution structure of human DJ-1, DTT bound 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Protein deglycase DJ-1 著者 Wilson, M.A, Lin, J. 登録日 2016-08-10 公開日 2016-12-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Short Carboxylic Acid-Carboxylate Hydrogen Bonds Can Have Fully Localized Protons. Biochemistry, 56, 2017
5SZV	Novel Structural Insights into GDP-Mediated Regulation of Acyl-CoA Thioesterases 分子名称: Acyl-CoA hydrolase, CHLORIDE ION, COENZYME A 著者 Khandokar, Y.B, Srivastava, P, Forwood, J.K. 登録日 2016-08-15 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural insights into GDP-mediated regulation of a bacterial acyl-CoA thioesterase. J. Biol. Chem., 292, 2017
5T1A	Structure of CC Chemokine Receptor 2 with Orthosteric and Allosteric Antagonists 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2~{R})-1-(4-chloranyl-2-fluoranyl-phenyl)-2-cyclohexyl-3-ethanoyl-4-oxidanyl-2~{H}-pyrrol-5-one, (3S)-1-{(1S,2R,4R)-4-[methyl(propan-2-yl)amino]-2-propylcyclohexyl}-3-{[6-(trifluoromethyl)quinazolin-4-yl]amino}pyrrolidin-2-one, ... 著者 Zheng, Y, Qin, L, Ortiz Zacarias, N.V, de Vries, H, Han, G.W, Gustavsson, M, Dabros, M, Zhao, C, Cherney, R.J, Carter, P, Stamos, D, Abagyan, R, Cherezov, V, Stevens, R.C, IJzerman, A.P, Heitman, L.H, Tebben, A, Kufareva, I, Handel, T.M. 登録日 2016-08-18 公開日 2016-12-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.806 Å) 主引用文献 Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists. Nature, 540, 2016
5SZY	Novel Structural Insights into GDP-Mediated Regulation of Acyl-CoA Thioesterases 分子名称: Acyl-CoA hydrolase, CHLORIDE ION, COENZYME A, ... 著者 Khandokar, Y.B, Srivastava, P, Forwood, J.K. 登録日 2016-08-15 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural insights into GDP-mediated regulation of a bacterial acyl-CoA thioesterase. J. Biol. Chem., 292, 2017
5T1Y	MLA10 coiled-coil fragment 分子名称: MLA10, TRIETHYLENE GLYCOL 著者 Williams, S.J, Kobe, B, Bentham, A, Ericsson, D.J. 登録日 2016-08-22 公開日 2016-11-02 最終更新日 2016-11-23 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The CC domain structure from the wheat stem rust resistance protein Sr33 challenges paradigms for dimerization in plant NLR proteins. Proc.Natl.Acad.Sci.USA, 2016
5T1H	Crystal structure of CK2 分子名称: 1,2-ETHANEDIOL, 7-(cyclopropylamino)-5-[3-(6-oxo-1,6-dihydropyridin-3-yl)thiophen-2-yl]pyrazolo[1,5-a]pyrimidine-3-carbonitrile, Casein kinase II subunit alpha, ... 著者 Feguson, A.D. 登録日 2016-08-19 公開日 2017-11-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Crystal structure of CK2 To Be Published
5T2W	Structure of thymine DNA glycosylase bound to substrate analog 2'-F-5-formyl-dC 分子名称: DNA (27-MER), DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase 著者 Pidugu, L.S, Pozharski, E, Drohat, A.C. 登録日 2016-08-24 公開日 2016-11-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Basis for Excision of 5-Formylcytosine by Thymine DNA Glycosylase. Biochemistry, 55, 2016
5T0Y	2A10 Antibody FAB fragment 分子名称: 2A10 FAB fragment heavy chain, 2A10 FAB fragment light chain, SULFATE ION 著者 Jackson, C.J, Fisher, C. 登録日 2016-08-17 公開日 2017-06-21 実験手法 X-RAY DIFFRACTION (3.011 Å) 主引用文献 Restricted antibody diversity and low affinity limit antibody responses to the Plasmodium circumsporozoite protein To Be Published
5T1U	Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality 分子名称: (4S)-4-[2,4-difluoro-5-({[1-(trifluoromethyl)cyclopropyl]amino}methyl)phenyl]-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine, 1,2-ETHANEDIOL, Beta-secretase 1, ... 著者 Parris, K.D, Vajdos, F. 登録日 2016-08-22 公開日 2017-01-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality. J. Med. Chem., 60, 2017
5T4Y	Crystal structure of BT1762-1763 分子名称: MAGNESIUM ION, SusC homolog, SusD homolog 著者 van den Berg, B. 登録日 2016-08-30 公開日 2016-12-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis for nutrient acquisition by dominant members of the human gut microbiota. Nature, 541, 2017
5T6C	Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a dichloro-methylpyridinyl-methoxy-phenyl-pyridine piperazine ligand 分子名称: 1-(4-{3,5-dichloro-4-[(2-methylpyridin-3-yl)methoxy]phenyl}pyridin-2-yl)piperazine, Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA 著者 Robinson, D.A, Wyatt, P.G. 登録日 2016-09-01 公開日 2017-09-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Design and Synthesis of Brain Penetrant Trypanocidal N-Myristoyltransferase Inhibitors. J. Med. Chem., 60, 2017
5T2T	Crystal structure of Lymphocytic choriomeningitis mammarenavirus endonuclease bound to compound L742001 分子名称: (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, CHLORIDE ION, GLYCEROL, ... 著者 Saez-Ayala, M, Yekwa, E.L, Canard, B, Alvarez, K, Ferron, F. 登録日 2016-08-24 公開日 2017-09-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.967 Å) 主引用文献 Crystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands. IUCrJ, 5, 2018
5T3Z	3.5 Angstrom Crystal Structure of a Fully and Natively Glycosylated BG505 SOSIP.664 HIV-1 Env Trimer in Complex with the Broadly Neutralizing Antibodies IOMA and 10-1074 分子名称: 10-1074 Heavy Chain, 10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Gristick, H.B, Bjorkman, P.J. 登録日 2016-08-26 公開日 2016-10-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site. Nat.Struct.Mol.Biol., 23, 2016
5T7U	Crystal structure of galectin-8N in complex with Glycerol 分子名称: CHLORIDE ION, GLYCEROL, Galectin-8, ... 著者 Bohari, M.H, Yu, X, Blanchard, H. 登録日 2016-09-05 公開日 2017-01-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Structure-based rationale for differential recognition of lacto- and neolacto- series glycosphingolipids by the N-terminal domain of human galectin-8. Sci Rep, 6, 2016
5T84	HIV-1 protease, unbound subtype B L63P construct 分子名称: Protease 著者 Liu, Z, Norell, J, Mahon, B, Poole, K, McKenna, R, Fanucci, G. 登録日 2016-09-06 公開日 2017-09-20 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Single mutation, L63P, capable of shutting down the flaps of HIV-1 protease To Be Published
5T6A	Crystal Structure of TgCDPK1 from toxoplasma gondii complexed with 5GA 分子名称: 4-(3-chloro-4-fluorophenyl)-5-(1,5-naphthyridin-2-yl)-1,3-thiazol-2-amine, Calmodulin-domain protein kinase 1 著者 Jiang, D.Q, Tempel, W, Loppnau, P, Walker, J.R, Graslund, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Lovato, D.V, Osman, K.T, Structural Genomics Consortium (SGC) 登録日 2016-09-01 公開日 2016-11-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal Structure of TgCDPK1 from toxoplasma gondii complexed with SGC-1-9 to be published
5T6I	CRYSTAL STRUCTURE OF TGCDPK1 FROM TOXOPLASMA GONDII COMPLEXED WITH 5GB 分子名称: 4-(3-methylphenyl)-5-(1,5-naphthyridin-2-yl)-1,3-thiazol-2-amine, Calmodulin-domain protein kinase 1 著者 Jiang, D.Q, Tempel, W, Walker, J.R, El Bakkouri, M, Loppnau, P, Graslund, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Lovato, D.V, Osman, K.T, Structural Genomics Consortium (SGC) 登録日 2016-09-01 公開日 2016-11-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal Structure of CDPK1 from toxoplasma gondii complexed with SGC-1-19 to be published
5T96	Crystal structure of the infectious salmon anemia virus (ISAV) HE viral receptor complex 分子名称: 4-O-acetyl-5-acetamido-3,5-dideoxy-L-glycero-alpha-D-galacto-non-2-ulopyranosonic acid, FORMIC ACID, GLYCEROL, ... 著者 Cook, J.D, Sultana, A, Lee, J.E. 登録日 2016-09-09 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the infectious salmon anemia virus receptor complex illustrates a unique binding strategy for attachment. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5TC2	C-terminal domain of HIV-1 integrase, crystal structure 分子名称: GLYCEROL, integrase 著者 Tsirkone, V.G, Strelkov, S.V. 登録日 2016-09-14 公開日 2018-04-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Interaction of TRN-SR2 with HIV Integrase To Be Published
5TC4	Crystal structure of human mitochondrial methylenetetrahydrofolate dehydrogenase-cyclohydrolase (MTHFD2) in complex with LY345899 and cofactors 分子名称: 4-(7-AMINO-9-HYDROXY-1-OXO-3,3A,4,5-TETRAHYDRO-2,5,6,8,9B-PENTAAZA-CYCLOPENTA[A]NAPHTHALEN-2-YL)-PHENYLCARBONYL-GLUTAMI C ACID, Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, ... 著者 Gustafsson, R, Jemth, A.-S, Gustafsson Sheppard, N, Farnegardh, K, Loseva, O, Wiita, E, Bonagas, N, Dahllund, L, Llona-Minguez, S, Haggblad, M, Henriksson, M, Andersson, Y, Homan, E, Helleday, T, Stenmark, P. 登録日 2016-09-14 公開日 2016-12-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor. Cancer Res., 77, 2017
5TFX	New method for synthesis of benzoxazole amide inhibitors of carbonic anhydrase 分子名称: Carbonic anhydrase 2, GLYCEROL, N-(5-sulfamoyl-1,3-benzoxazol-2-yl)benzamide, ... 著者 Peat, T.S, Supuran, C. 登録日 2016-09-26 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Intramolecular oxidative deselenization of acylselenoureas: a facile synthesis of benzoxazole amides and carbonic anhydrase inhibitors. Org. Biomol. Chem., 14, 2016
5TC9	Wild type TrCel7A catalytic domain in a closed state 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GADOLINIUM ION, Glucanase, ... 著者 Bodenheimer, A.M, Meilleur, F. 登録日 2016-09-14 公開日 2017-01-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structures of wild-type Trichoderma reesei Cel7A catalytic domain in open and closed states. FEBS Lett., 590, 2016
5TD8	Crystal structure of an Extended Dwarf Ndc80 Complex 分子名称: Kinetochore protein NDC80, Kinetochore protein NUF2, Kinetochore protein SPC24, ... 著者 Valverde, R, Ingram, J, Harrison, S.C. 登録日 2016-09-17 公開日 2016-11-16 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (7.531 Å) 主引用文献 Conserved Tetramer Junction in the Kinetochore Ndc80 Complex. Cell Rep, 17, 2016

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