PDB: 46006 件ウェブページステータス検索Chemie searchBIRD

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6HGH	Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin without any bound ligand 分子名称: Alpha-1-antichymotrypsin, MALONIC ACID, alpha1-Antichymotrypsin 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
6RCI	Crystal structure of REXO2 分子名称: Oligoribonuclease, mitochondrial 著者 Spahr, H, Nicholls, T.J, Larsson, N.G, Gustafsson, C.M. 登録日 2019-04-11 公開日 2019-10-09 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria. Mol.Cell, 76, 2019
5ZYA	SF3b spliceosomal complex bound to E7107 分子名称: PHD finger-like domain-containing protein 5A, POTASSIUM ION, Splicing factor 3B subunit 1, ... 著者 Finci, L.I, Larsen, N.A. 登録日 2018-05-23 公開日 2018-06-20 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.95 Å) 主引用文献 The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action Genes Dev., 32, 2018
3H13	c-FLIPL protease-like domain 分子名称: CASP8 and FADD-like apoptosis regulator 著者 Jeffrey, P.D, Yu, J.W, Shi, Y. 登録日 2009-04-10 公開日 2009-04-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Mechanism of procaspase-8 activation by c-FLIPL. Proc.Natl.Acad.Sci.USA, 106, 2009
6HGI	Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with corticosterone 分子名称: Alpha-1-antichymotrypsin, CORTICOSTERONE 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.517 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
3H73	Crystal structure of Streptococcus pneumoniae D39 neuraminidase A precursor (NanA) in complex with DANA 分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, Sialidase A 著者 Hsiao, Y.-S, Tong, L. 登録日 2009-04-24 公開日 2009-05-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structures of respiratory pathogen neuraminidases Biochem.Biophys.Res.Commun., 380, 2009
6A5Z	Crystal structure of human FXR/RXR-LBD heterodimer bound to HNC180 and 9cRA and SRC1 分子名称: (9cis)-retinoic acid, 2-[(1R,5S)-9-[[3-[2,6-bis(chloranyl)phenyl]-5-cyclopropyl-1,2-oxazol-4-yl]methoxy]-3-azabicyclo[3.3.1]nonan-3-yl]-1,3-benzothiazole-6-carboxylic acid, Bile acid receptor, ... 著者 Wang, N, Liu, J. 登録日 2018-06-25 公開日 2018-10-10 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding J. Biol. Chem., 293, 2018
7WDC	Crystal Structure of Cyanobacterial Circadian Clock Protein KaiC 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION 著者 Furuike, Y, Akiyama, S. 登録日 2021-12-21 公開日 2022-07-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Highly sensitive tryptophan fluorescence probe for detecting rhythmic conformational changes of KaiC in the cyanobacterial circadian clock system. Biochem.J., 479, 2022
3H43	N-terminal domain of the proteasome-activating nucleotidase of Methanocaldococcus jannaschii 分子名称: Proteasome-activating nucleotidase 著者 Jeffrey, P.D, Zhang, F, Hu, M, Tian, G, Zhang, P, Finley, D, Shi, Y. 登録日 2009-04-17 公開日 2009-06-09 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii. Mol.Cell, 34, 2009
5ZWF	Covalent bond formation between histidine of Vitamin D receptor (VDR) and a full agonist having a enone with a beta methyl group via conjugate addition reaction 分子名称: (E,7R)-7-[(1R,3aS,4E,7aR)-7a-methyl-4-[2-[(3R,5R)-4-methylidene-3,5-bis(oxidanyl)cyclohexylidene]ethylidene]-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]oct-2-en-4-one, 13-meric peptide from DRIP205 NR2 BOX peptide, Vitamin D3 receptor 著者 Yoshizawa, M, Itoh, T, Anami, Y, Kato, A, Yoshimoto, N, Yamamoto, K. 登録日 2018-05-15 公開日 2018-07-18 最終更新日 2018-08-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Identification of the Histidine Residue in Vitamin D Receptor That Covalently Binds to Electrophilic Ligands J. Med. Chem., 61, 2018
2YQE	Solution structure of the ARID domain of JARID1D protein 分子名称: Jumonji/ARID domain-containing protein 1D 著者 Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-30 公開日 2008-04-01 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the ARID domain of JARID1D protein To be Published
3TB7	The type I crystal structure of Streptococcus agalactiae sortase C1 分子名称: Sortase family protein 著者 Khare, B. 登録日 2011-08-05 公開日 2011-10-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The Crystal Structure Analysis of Group B Streptococcus Sortase C1: A Model for the "Lid" Movement upon Substrate Binding. J.Mol.Biol., 414, 2011
3T1H	Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA lysine 3 (tRNALys3) bound to an mRNA with an AAA-codon in the A-site and Paromomycin 分子名称: 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Murphy, F.V, Vendeix, F.A.P, Cantara, W, Leszczynska, G, Gustilo, E.M, Sproat, B, Malkiewicz, A.A.P, Agris, P.F. 登録日 2011-07-21 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism. J.Mol.Biol., 416, 2012
2YEU	Structural and functional insights of DR2231 protein, the MazG-like nucleoside triphosphate pyrophosphohydrolase from Deinococcus radiodurans, complex with Gd 分子名称: DR2231, GADOLINIUM ATOM, GLYCEROL, ... 著者 Goncalves, A.M.D, de Sanctis, D, McSweeney, S.M. 登録日 2011-03-30 公開日 2011-07-06 最終更新日 2011-09-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and Functional Insights Into Dr2231 Protein, the Mazg-Like Nucleoside Triphosphate Pyrophosphohydrolase from Deinococcus Radiodurans. J.Biol.Chem., 286, 2011
3T7T	Crystal structure of complex of SAH and BVU_3255, a methyltransferase from Bacteroides vulgatus ATCC 8482 分子名称: Putative methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Kumar, V, Sivaraman, J. 登録日 2011-07-31 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural characterization of BVU_3255, a methyltransferase from human intestine antibiotic resistant pathogen Bacteroides vulgatus J.Struct.Biol., 2011
3H72	Crystal structure of Streptococcus pneumoniae D39 neuraminidase A precursor (NanA) in complex with NANA 分子名称: N-acetyl-alpha-neuraminic acid, Sialidase A 著者 Hsiao, Y.-S, Tong, L. 登録日 2009-04-24 公開日 2009-05-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structures of respiratory pathogen neuraminidases Biochem.Biophys.Res.Commun., 380, 2009
3TBG	Human cytochrome P450 2D6 with two thioridazines bound in active site 分子名称: 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, Cytochrome P450 2D6, GLYCEROL, ... 著者 Wang, A, Stout, C.D, Johnson, E.F. 登録日 2011-08-05 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding. J.Biol.Chem., 290, 2015
6A22	Ternary complex of Human ROR gamma Ligand Binding Domain With Compound T. 分子名称: 2-[2-[1-~{tert}-butyl-5-(4-methoxyphenyl)pyrazol-4-yl]-1,3-thiazol-4-yl]-~{N}-(oxan-4-ylmethyl)ethanamide, Nuclear receptor ROR-gamma, Nuclear receptor corepressor 2 著者 Noguchi, M, Nomura, A, Doi, S, Yamaguchi, K, Adachi, T. 登録日 2018-06-08 公開日 2018-12-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Ternary crystal structure of human ROR gamma ligand-binding-domain, an inhibitor and corepressor peptide provides a new insight into corepressor interaction Sci Rep, 8, 2018
4P0H	Crystal Structure Analysis of Macrophage Migration Inhibitory Factor in complex with Dimethylformamide 分子名称: DIMETHYLFORMAMIDE, GLYCEROL, Macrophage migration inhibitory factor 著者 Pantouris, G, Lolis, E. 登録日 2014-02-21 公開日 2014-04-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
3S9B	Russell's viper venom serine proteinase, RVV-V (open-form) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Vipera russelli proteinase RVV-V gamma 著者 Nakayama, D, Ben Ammar, Y, Takeda, S. 登録日 2011-06-01 公開日 2011-09-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis of coagulation factor V recognition for cleavage by RVV-V Febs Lett., 585, 2011
3GW7	Crystal structure of a metal-dependent phosphohydrolase with conserved HD domain (yedJ) from Escherichia coli in complex with nickel ions. Northeast Structural Genomics Consortium Target ER63 分子名称: NICKEL (II) ION, Uncharacterized protein yedJ 著者 Forouhar, F, Abashidze, M, Seetharaman, J, Janjua, J, Xiao, R, Cunningham, K, Ma, L, Zhao, L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2009-03-31 公開日 2009-04-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Crystal structure of a metal-dependent phosphohydrolase with conserved HD domain (yedJ) from Escherichia coli in complex with nickel ions. Northeast Structural Genomics Consortium Target ER63 To be Published
1DDL	DESMODIUM YELLOW MOTTLE TYMOVIRUS 分子名称: DESMODIUM YELLOW MOTTLE VIRUS, RNA (5'-R(P*UP*U)-3'), RNA (5'-R(P*UP*UP*UP*UP*UP*UP*U)-3') 著者 Larson, S.B, Day, J, Canady, M.A, Greenwood, A, McPherson, A. 登録日 1999-11-10 公開日 2000-10-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Refined structure of desmodium yellow mottle tymovirus at 2.7 A resolution. J.Mol.Biol., 301, 2000
5ZWE	Covalent bond formation between histidine of Vitamin D receptor (VDR) and a full agonist having a vinyl ketone group via conjugate addition reaction 分子名称: (6R)-6-[(1R,3aS,4E,7aR)-7a-methyl-4-[2-[(3R,5R)-4-methylidene-3,5-bis(oxidanyl)cyclohexylidene]ethylidene]-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]hept-1-en-3-one, 13-meric peptide from DRIP205 NR2 BOX peptide, Vitamin D3 receptor 著者 Yoshizawa, M, Itoh, T, Anami, Y, Kato, A, Yoshimoto, N, Yamamoto, K. 登録日 2018-05-15 公開日 2018-07-18 最終更新日 2018-08-08 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Identification of the Histidine Residue in Vitamin D Receptor That Covalently Binds to Electrophilic Ligands J. Med. Chem., 61, 2018
7W3Q	Crystal structure of RORgamma in complex with natural inverse agonist 分子名称: (3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-4,4,8,10,14-pentamethyl-17-[(2R)-6-methyl-2-oxidanyl-hept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6,12-triol, Nuclear receptor ROR-gamma, Peptide from Nuclear receptor coactivator 2 著者 Tian, S.Y, Li, Y. 登録日 2021-11-25 公開日 2022-12-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of RORgamma in complex with natural inverse agonist To Be Published
1MFI	CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR COMPLEXED WITH (E)-2-FLUORO-P-HYDROXYCINNAMATE 分子名称: 2-FLUORO-3-(4-HYDROXYPHENYL)-2E-PROPENEOATE, PROTEIN (MACROPHAGE MIGRATION INHIBITORY FACTOR) 著者 Taylor, A.B, Johnson Jr, W.H, Czerwinski, R.M, Whitman, C.P, Hackert, M.L. 登録日 1998-08-12 公開日 1999-06-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of macrophage migration inhibitory factor complexed with (E)-2-fluoro-p-hydroxycinnamate at 1.8 A resolution: implications for enzymatic catalysis and inhibition. Biochemistry, 38, 1999

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