PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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5F0Q	Crystal structure of C-terminal domain of the human DNA primase large subunit with bound DNA template/RNA primer 分子名称: DNA (5'-D(*GP*CP*CP*GP*CP*CP*AP*AP*CP*AP*TP*A)-3'), DNA primase large subunit, IRON/SULFUR CLUSTER, ... 著者 Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. 登録日 2015-11-28 公開日 2016-03-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome. J.Biol.Chem., 291, 2016
5OR5	NMR structure of the complex formed by an engineered region 2 of sigmaE in complex with GTAAAA 分子名称: DNA (5'-D(*GP*TP*AP*AP*AP*A)-3'), ECF RNA polymerase sigma-E factor,ECF RNA polymerase sigma factor SigW,ECF RNA polymerase sigma-E factor 著者 Campagne, S, Vorholt, J.A, Allain, F.H. 登録日 2017-08-15 公開日 2018-06-27 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Engineered promoter selectivity of an ECF sigma factor Not published
6ZOK	SARS-CoV-2-Nsp1-40S complex, focused on body 分子名称: 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ... 著者 Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M, Thiel, V, Muehlemann, O, Ban, N. 登録日 2020-07-07 公開日 2020-07-29 最終更新日 2021-02-10 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat.Struct.Mol.Biol., 27, 2020
5UHB	Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with Rifampin 分子名称: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-11 公開日 2017-04-12 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (4.29 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
5UHF	Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with D-IX336 分子名称: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-11 公開日 2017-04-12 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (4.345 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
5UHG	Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with D-AAP1 and Rifampin 分子名称: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-11 公開日 2017-04-12 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (3.971 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
7LYF	Dengue virus RNA promoter stem-loop A fused with tRNA-scaffold 分子名称: MAGNESIUM ION, RNA promoter stem-loop A fused with tRNA 著者 Lee, E.H, Choi, K.H. 登録日 2021-03-06 公開日 2021-05-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structures of flavivirus RNA promoters suggest two binding modes with NS5 polymerase. Nat Commun, 12, 2021
6DVD	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) with 6 nt spacer and bromine labelled in position "-11 分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*A)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2018-06-23 公開日 2019-02-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.899 Å) 主引用文献 Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
7S0T	Structure of DNA polymerase zeta with mismatched DNA 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ... 著者 Malik, R, Ubarretxena, I.B, Aggarwal, A.K. 登録日 2021-08-31 公開日 2022-03-09 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.05 Å) 主引用文献 Cryo-EM structure of translesion DNA synthesis polymerase zeta with a base pair mismatch. Nat Commun, 13, 2022
1NKE	A BACILLUS DNA POLYMERASE I PRODUCT COMPLEX BOUND TO A CYTOSINE-THYMINE MISMATCH AFTER A SINGLE ROUND OF PRIMER EXTENSION, FOLLOWING INCORPORATION OF DCTP. 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA POLYMERASE I, DNA PRIMER STRAND, ... 著者 Johnson, S.J, Beese, L.S. 登録日 2003-01-02 公開日 2004-03-30 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of mismatch replication errors observed in a DNA polymerase. Cell(Cambridge,Mass.), 116, 2004
4G7H	Crystal structure of Thermus thermophilus transcription initiation complex 分子名称: 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', DNA-directed RNA polymerase subunit alpha, ... 著者 Zhang, Y, Ebright, R.H. 登録日 2012-07-20 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of transcription initiation. Science, 338, 2012
4G7Z	Crystal structure of Thermus thermophilus transcription initiation complex containing 5-BrU at template-strand position +1 分子名称: 5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*(BRU)P*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', DNA-directed RNA polymerase subunit alpha, ... 著者 Zhang, Y, Ebright, R.H. 登録日 2012-07-20 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.815 Å) 主引用文献 Structural basis of transcription initiation. Science, 338, 2012
5UHE	Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with D-AAP1 分子名称: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-11 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4.039 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
4FXD	Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA 分子名称: DNA (5'-D(*TP*TP*TP*TP*CP*GP*CP*TP*GP*CP*CP*CP*GP*CP*CP*T)-3'), DNA polymerase alpha catalytic subunit A, RNA (5'-R(*AP*GP*GP*CP*GP*GP*GP*CP*AP*G)-3') 著者 Perera, R.L, Torella, R, Klinge, S, Kilkenny, M.L, Maman, J.D, Pellegrini, L. 登録日 2012-07-03 公開日 2013-02-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha eLife, 2, 2013
6HAK	Crystal structure of HIV-1 reverse transcriptase (RT) in complex with a double stranded RNA represents the RT transcription initiation complex prior to nucleotide incorporation 分子名称: Gag-Pol polyprotein, MAGNESIUM ION, RNA (5'-R(P*AP*GP*UP*GP*GP*CP*GP*GP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*C)-3'), ... 著者 Das, K, Martinez, S.E, Arnold, E. 登録日 2018-08-07 公開日 2019-04-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.95 Å) 主引用文献 Structure of HIV-1 RT/dsRNA initiation complex prior to nucleotide incorporation. Proc.Natl.Acad.Sci.USA, 116, 2019
5TMC	Re-refinement of Thermus thermopiles DNA-directed RNA polymerase structure 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Wang, J. 登録日 2016-10-12 公開日 2016-11-23 最終更新日 2019-02-20 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 On the validation of crystallographic symmetry and the quality of structures. Protein Sci., 24, 2015
1NK4	GUANINE-GUANINE MISMATCH AT THE POLYMERASE ACTIVE SITE 分子名称: DNA POLYMERASE I, DNA PRIMER STRAND, DNA TEMPLATE STRAND, ... 著者 Johnson, S.J, Beese, L.S. 登録日 2003-01-02 公開日 2004-03-30 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structures of mismatch replication errors observed in a DNA polymerase. Cell(Cambridge,Mass.), 116, 2004
1NJZ	CYTOSINE-THYMINE MISMATCH AT THE POLYMERASE ACTIVE SITE 分子名称: DNA POLYMERASE I, DNA PRIMER STRAND, DNA TEMPLATE STRAND, ... 著者 Johnson, S.J, Beese, L.S. 登録日 2003-01-02 公開日 2004-03-30 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of mismatch replication errors observed in a DNA polymerase. Cell(Cambridge,Mass.), 116, 2004
5UHA	Crystal structure of Mycobacterium tuberculosis transcription initiation complex 分子名称: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-11 公開日 2017-04-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.906 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
6MVQ	HCV NS5B 1b N316 bound to Compound 31 分子名称: (4-{1-[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl]-1H-1,2,4-triazol-5-yl}-2-fluorophenyl)boronic acid, HCV Polymerase 著者 Williams, S.P, Kahler, K, Price, D.J, Peat, A.J. 登録日 2018-10-26 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Design of N-Benzoxaborole Benzofuran GSK8175-Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor. J.Med.Chem., 62, 2019
4IUU	Crystal structure of SHH1 SAWADEE domain in complex with H3K9me1 peptide 分子名称: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ... 著者 Du, J, Patel, D.J. 登録日 2013-01-21 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1. Nature, 498, 2013
4IUR	crystal structure of SHH1 SAWADEE domain in complex with H3K9me3 peptide 分子名称: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ... 著者 Patel, D.J, Du, J. 登録日 2013-01-21 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1. Nature, 498, 2013
4IUV	crystal structure of SHH1 SAWADEE domain in complex with H3K4me1K9me1 peptide 分子名称: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ... 著者 Du, J, Patel, D.J. 登録日 2013-01-21 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1. Nature, 498, 2013
4IUT	crystal structure of SHH1 SAWADEE domain in complex with H3K9me2 peptide 分子名称: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ... 著者 Du, J, Patel, D.J. 登録日 2013-01-21 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1. Nature, 498, 2013
5J1N	Lassa virus L protein cap-snatching endonuclease. Bound to one manganese ion 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, MANGANESE (III) ION, RNA-directed RNA polymerase L 著者 Reguera, J, Cusack, S. 登録日 2016-03-29 公開日 2016-06-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases. Plos Pathog., 12, 2016

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