PDB: 13413 件ウェブページステータス検索Chemie searchBIRD

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4WLW	CRYSTAL STRUCTURE OF THE AG(I) (ACTIVATOR) FORM OF E. COLI CUER, A COPPER EFFLUX REGULATOR, BOUND TO COPA PROMOTER DNA 分子名称: DNA NON-TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP *DTP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DGP*DCP*DTP*DGP*DGP*DAP *DAP*DGP*DGP*DTP*DC)-3, DNA TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP*DTP *DTP*DCP*DCP*DAP*DGP*DCP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DAP *DGP*DGP*DTP*DC)-3, HTH-type transcriptional regulator CueR, ... 著者 Philips, S.J, Canalizo-Hernandez, M, Mondragon, A, O'Halloran, T.V. 登録日 2014-10-08 公開日 2015-09-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter. Science, 349, 2015
8G9N	Partial DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ... 著者 Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. 登録日 2023-02-21 公開日 2023-04-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
8G9O	Complete DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ... 著者 Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. 登録日 2023-02-21 公開日 2023-04-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
1N35	lambda3 elongation complex with four phosphodiester bond formed 分子名称: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*CP*CP*CP*CP*C)-3', 5'-R(P*GP*GP*GP*GP*G)-3', ... 著者 Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C. 登録日 2002-10-25 公開日 2002-12-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3 Cell(Cambridge,Mass.), 111, 2002
6MVQ	HCV NS5B 1b N316 bound to Compound 31 分子名称: (4-{1-[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl]-1H-1,2,4-triazol-5-yl}-2-fluorophenyl)boronic acid, HCV Polymerase 著者 Williams, S.P, Kahler, K, Price, D.J, Peat, A.J. 登録日 2018-10-26 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Design of N-Benzoxaborole Benzofuran GSK8175-Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor. J.Med.Chem., 62, 2019
6ERP	Structure of the human mitochondrial transcription initiation complex at the LSP promoter 分子名称: DNA-directed RNA polymerase, mitochondrial, Dimethyladenosine transferase 2, ... 著者 Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P. 登録日 2017-10-18 公開日 2017-11-15 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (4.502 Å) 主引用文献 Structural Basis of Mitochondrial Transcription Initiation. Cell, 171, 2017
8G9L	DNA initiation subcomplex of Xenopus laevis DNA polymerase alpha-primase 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ... 著者 Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. 登録日 2023-02-21 公開日 2023-04-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
7UIG	Mediator-PIC Early (Mediator A) 分子名称: DNA-directed RNA polymerase II subunit RPB1, Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, ... 著者 Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. 登録日 2022-03-29 公開日 2023-02-15 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol.Cell, 83, 2023
7ABH	Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion) 分子名称: Cell division cycle 5-like protein, DNA/RNA-binding protein KIN17, MINX M3 pre-mRNA, ... 著者 Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. 登録日 2020-09-07 公開日 2020-12-09 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
5EXR	Crystal structure of human primosome 分子名称: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... 著者 Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. 登録日 2015-11-24 公開日 2016-03-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome. J.Biol.Chem., 291, 2016
7ABF	Human pre-Bact-1 spliceosome core structure 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. 登録日 2020-09-07 公開日 2020-12-09 最終更新日 2020-12-30 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
6WYB	RTX (Reverse Transcription Xenopolymerase) in complex with an RNA/DNA hybrid 分子名称: 1,2-ETHANEDIOL, 3,3',3''-phosphanetriyltripropanoic acid, DNA polymerase, ... 著者 Choi, W.S, He, P, Pothukuchy, A, Gollihar, J, Ellington, A.D, Yang, W. 登録日 2020-05-12 公開日 2020-08-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 How a B family DNA polymerase has been evolved to copy RNA. Proc.Natl.Acad.Sci.USA, 117, 2020
6ZOL	SARS-CoV-2-Nsp1-40S complex, focused on head 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ... 著者 Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M.L, Thiel, V, Muehlemann, O, Ban, N. 登録日 2020-07-07 公開日 2020-07-22 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat.Struct.Mol.Biol., 27, 2020
7LYF	Dengue virus RNA promoter stem-loop A fused with tRNA-scaffold 分子名称: MAGNESIUM ION, RNA promoter stem-loop A fused with tRNA 著者 Lee, E.H, Choi, K.H. 登録日 2021-03-06 公開日 2021-05-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structures of flavivirus RNA promoters suggest two binding modes with NS5 polymerase. Nat Commun, 12, 2021
4V9E	Crystal Structure of Rift Valley Fever Virus Nucleocapsid Protein Hexamer Bound to Single-stranded RNA. 分子名称: 35-mer poly(U) RNA, Nucleocapsid protein 著者 Raymond, D.D, Smith, J.L. 登録日 2012-09-19 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Phleboviruses encapsidate their genomes by sequestering RNA bases. Proc.Natl.Acad.Sci.USA, 109, 2012
1NKE	A BACILLUS DNA POLYMERASE I PRODUCT COMPLEX BOUND TO A CYTOSINE-THYMINE MISMATCH AFTER A SINGLE ROUND OF PRIMER EXTENSION, FOLLOWING INCORPORATION OF DCTP. 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA POLYMERASE I, DNA PRIMER STRAND, ... 著者 Johnson, S.J, Beese, L.S. 登録日 2003-01-02 公開日 2004-03-30 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of mismatch replication errors observed in a DNA polymerase. Cell(Cambridge,Mass.), 116, 2004
6WYA	RTX (Reverse Transcription Xenopolymerase) in complex with a DNA duplex and dAMPNPP 分子名称: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Choi, W.S, He, P, Pothukuchy, A, Gollihar, J, Ellington, A.D, Yang, W. 登録日 2020-05-12 公開日 2020-08-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 How a B family DNA polymerase has been evolved to copy RNA. Proc.Natl.Acad.Sci.USA, 117, 2020
6JNX	Cryo-EM structure of a Q-engaged arrested complex 分子名称: Antiterminator Q protein, DNA (63-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Feng, Y, Shi, J. 登録日 2019-03-18 公開日 2019-06-12 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.08 Å) 主引用文献 Structural basis of Q-dependent transcription antitermination. Nat Commun, 10, 2019
1NK4	GUANINE-GUANINE MISMATCH AT THE POLYMERASE ACTIVE SITE 分子名称: DNA POLYMERASE I, DNA PRIMER STRAND, DNA TEMPLATE STRAND, ... 著者 Johnson, S.J, Beese, L.S. 登録日 2003-01-02 公開日 2004-03-30 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structures of mismatch replication errors observed in a DNA polymerase. Cell(Cambridge,Mass.), 116, 2004
1NJZ	CYTOSINE-THYMINE MISMATCH AT THE POLYMERASE ACTIVE SITE 分子名称: DNA POLYMERASE I, DNA PRIMER STRAND, DNA TEMPLATE STRAND, ... 著者 Johnson, S.J, Beese, L.S. 登録日 2003-01-02 公開日 2004-03-30 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of mismatch replication errors observed in a DNA polymerase. Cell(Cambridge,Mass.), 116, 2004
4U6O	STRUCTURE OF THE CAP-BINDING DOMAIN OF INFLUENZA VIRUS POLYMERASE SUBUNIT PB2 分子名称: PHOSPHATE ION, Polymerase basic protein 2 著者 Fukushima, K, Takimoto-Kamimura, M. 登録日 2014-07-29 公開日 2015-10-07 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 STRUCTURE OF THE CAP-BINDING DOMAIN OF INFLUENZA VIRUS POLYMERASE SUBUNIT PB2 To Be Published
7VWZ	Cryo-EM structure of Rob-dependent transcription activation complex in a unique conformation 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Lin, W, Feng, Y, Shi, J. 登録日 2021-11-12 公開日 2022-06-08 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator. Nucleic Acids Res., 50, 2022
5IZE	Hantaan virus L protein cap-snatching endonuclease 分子名称: MANGANESE (III) ION, RNA-directed RNA polymerase L 著者 Reguera, J, Cusack, S. 登録日 2016-03-25 公開日 2016-06-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases. Plos Pathog., 12, 2016
5J1P	Lassa virus L protein cap-snatching endonuclease. Bound to two manganese ions 分子名称: MANGANESE (III) ION, RNA-directed RNA polymerase L 著者 Reguera, J, Cusack, S. 登録日 2016-03-29 公開日 2016-06-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases. Plos Pathog., 12, 2016
5J1N	Lassa virus L protein cap-snatching endonuclease. Bound to one manganese ion 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, MANGANESE (III) ION, RNA-directed RNA polymerase L 著者 Reguera, J, Cusack, S. 登録日 2016-03-29 公開日 2016-06-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases. Plos Pathog., 12, 2016

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