PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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8U5Y	human RADX trimer bound to ssDNA 分子名称: DNA (25-MER), RPA-related protein RADX 著者 Balakrishnan, S, Chazin, W.J. 登録日 2023-09-13 公開日 2023-10-11 最終更新日 2023-10-18 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Structure of RADX and mechanism for regulation of RAD51 nucleofilaments. Biorxiv, 2023
8U5T	Structure of Mango II variant aptamer bound to T01-6A-B 分子名称: 3-{2,16-dioxo-20-[(3aS,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-6,9,12-trioxa-3,15-diazaicosan-1-yl}-2-{(E)-[6-(4-methoxyphenyl)-1-methylquinolin-4(1H)-ylidene]methyl}-1,3-benzothiazol-3-ium, Mango II variant, POTASSIUM ION, ... 著者 Passalacqua, L.F.M, Ferre-D'Amare, A.R. 登録日 2023-09-12 公開日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of Mango II variant aptamer bound to T01-6A-B To Be Published
8U5R	Structure of Mango II variant aptamer bound to T01-6A 分子名称: Mango II variant, POTASSIUM ION, SODIUM ION 著者 Passalacqua, L.F.M, Ferre-D'Amare, A.R. 登録日 2023-09-12 公開日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of Mango II variant aptamer bound to T01-6A To Be Published
8U5P	Structure of Mango II aptamer bound to T01-6A-B 分子名称: 3-[2,16-dioxo-20-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-6,9,12-trioxa-3,15-diazaicosan-1-yl]-2-{(E)-[6-(4-methoxyphenyl)-1-methylquinolin-4(1H)-ylidene]methyl}-1,3-benzothiazol-3-ium, Mango II, POTASSIUM ION 著者 Passalacqua, L.F.M, Ferre-D'Amare, A.R. 登録日 2023-09-12 公開日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of Mango II aptamer bound to T01-6A-B To Be Published
8U5M	Structure of Sts-1 HP domain with rebamipide 分子名称: Rebamipide, Ubiquitin-associated and SH3 domain-containing protein B 著者 Azia, F, Dey, R, French, J.B. 登録日 2023-09-12 公開日 2024-02-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Rebamipide and Derivatives are Potent, Selective Inhibitors of Histidine Phosphatase Activity of the Suppressor of T Cell Receptor Signaling Proteins. J.Med.Chem., 67, 2024
8U5K	Structure of Mango II aptamer bound to T01-6A 分子名称: 2-[(~{E})-[6-(4-methoxyphenyl)-1-methyl-quinolin-4-ylidene]methyl]-3-methyl-1,3-benzothiazole, Mango II, POTASSIUM ION 著者 Passalacqua, L.F.M, Ferre-D'Amare, A.R. 登録日 2023-09-12 公開日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of Mango II aptamer bound to T01-6A To Be Published
8U5J	Structure of Mango III variant aptamer bound to T01-07M-B 分子名称: 2-[(E)-(1,7-dimethylquinolin-4(1H)-ylidene)methyl]-3-{2,16-dioxo-20-[(3aR,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-6,9,12-trioxa-3,15-diazaicosan-1-yl}-1,3-benzothiazol-3-ium, DIMETHYL SULFOXIDE, Mango III variant, ... 著者 Passalacqua, L.F.M, Ferre-D'Amare, A.R. 登録日 2023-09-12 公開日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of Mango III variant aptamer bound to T01-07M-B To Be Published
8U5H	Cryo-EM structure of human DNMT3A UDR bound to H2AK119ub1-modified nucleosome 分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone H2A, Histone H2B 1.1, ... 著者 Chen, X, Song, J. 登録日 2023-09-12 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Cryo-EM structure of human DNMT3A N-terminal domain bound to H2AK119Ub nucleosome To Be Published
8U5G	Crystal structure of the co-expressed SDS22:PP1:I3 complex 分子名称: E3 ubiquitin-protein ligase PPP1R11, FE (III) ION, PHOSPHATE ION, ... 著者 Choy, M.S, Peti, W, Page, R. 登録日 2023-09-12 公開日 2023-12-06 最終更新日 2024-01-03 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The SDS22:PP1:I3 complex: SDS22 binding to PP1 loosens the active site metal to prime metal exchange. J.Biol.Chem., 300, 2023
8U5F	Crystal Structure of Trypsinized Clostridium perfringens Enterotoxin 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Heat-labile enterotoxin B chain, ... 著者 Kapoor, S, Ogbu, C.P, Vecchio, A.J. 登録日 2023-09-12 公開日 2023-09-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Structural Basis of Clostridium perfringens Enterotoxin Activation and Oligomerization by Trypsin. Toxins, 15, 2023
8U5E	Crystal Structure of C-terminal domain of Clostridium perfringens Enterotoxin in Space Group P 21 21 21 分子名称: ACETATE ION, GLYCEROL, Heat-labile enterotoxin B chain, ... 著者 Kapoor, S, Vecchio, A.J. 登録日 2023-09-12 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural Basis of Clostridium perfringens Enterotoxin Activation and Oligomerization by Trypsin. Toxins, 15, 2023
8U5D	Crystal Structure of C-terminal domain of Clostridium perfringens Enterotoxin in Space Group P 41 21 2 分子名称: ACETATE ION, GLYCEROL, Heat-labile enterotoxin B chain, ... 著者 Kapoor, S, Vecchio, A.J. 登録日 2023-09-12 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural Basis of Clostridium perfringens Enterotoxin Activation and Oligomerization by Trypsin. Toxins, 15, 2023
8U5B	Cryo-EM structure of human claudin-4 complex with Clostridium perfringens enterotoxin C-terminal domain and sFab COP-1 分子名称: COP-1 sFab Heavy Chain, COP-1 sFab Light Chain, Claudin-4, ... 著者 Vecchio, A.J. 登録日 2023-09-12 公開日 2023-09-27 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (5.3 Å) 主引用文献 Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment. Commun Biol, 7, 2024
8U5A	Improving protein expression, stability, and function with ProteinMPNN 分子名称: Designed myoglobin, PROTOPORPHYRIN IX CONTAINING FE 著者 Kalvet, I, Bera, A.K, Baker, D. 登録日 2023-09-12 公開日 2024-01-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Improving Protein Expression, Stability, and Function with ProteinMPNN. J.Am.Chem.Soc., 146, 2024
8U55	Crystal structure of Enterococcus faecium EnGen25 Penicillin-binding protein 5 (PBP5) 分子名称: Penicillin-binding protein 5 著者 Pemberton, O.A, Shamoo, Y. 登録日 2023-09-12 公開日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of Enterococcus faecium EnGen25 Penicillin-binding protein 5 (PBP5) To Be Published
8U53	Mechanically activated ion channel OSCA3.1 in nanodiscs 分子名称: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CSC1-like protein ERD4, PALMITIC ACID, ... 著者 Jojoa-Cruz, S, Lee, W.H, Ward, A.B. 登録日 2023-09-12 公開日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structure-guided mutagenesis of OSCAs reveals differential activation to mechanical stimuli. Elife, 12, 2024
8U51	Klebsiella pneumoniae SUMO-loaded encapsulin shell 分子名称: Klebsiella pneumoniae family 1 encapsulin shell, SUMO-targeting peptide fusion protein 著者 Andreas, M.P, Jones, J.A, Giessen, T.W. 登録日 2023-09-11 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.41 Å) 主引用文献 Structural basis for peroxidase encapsulation inside the encapsulin from the Gram-negative pathogen Klebsiella pneumoniae. Nat Commun, 15, 2024
8U50	Klebsiella pneumoniae DyP peroxidase-loaded encapsulin shell 分子名称: Klebsiella pneumoniae family 1 encapsulin shell 著者 Andreas, M.P, Jones, J.A, Giessen, T.W. 登録日 2023-09-11 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.52 Å) 主引用文献 Structural basis for peroxidase encapsulation inside the encapsulin from the Gram-negative pathogen Klebsiella pneumoniae. Nat Commun, 15, 2024
8U4Z	Klebsiella pneumoniae encapsulin-associated DyP peroxidase 分子名称: Family 1 encapsulin-associated DyP peroxidase, Mesoheme 著者 Andreas, M.P, Jones, J.A, Giessen, T.W. 登録日 2023-09-11 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.39 Å) 主引用文献 Structural basis for peroxidase encapsulation inside the encapsulin from the Gram-negative pathogen Klebsiella pneumoniae. Nat Commun, 15, 2024
8U4W	The crystal structure of a helical domain deleted PARP1 in complex with isoindolinone based inhibitor. 分子名称: (4M)-4-(2-{4-[(3S)-1-acetylpiperidine-3-carbonyl]piperazine-1-carbonyl}-1-benzofuran-7-yl)-1H-isoindol-1-one, Poly [ADP-ribose] polymerase 1, processed C-terminus 著者 Marcotte, D.J. 登録日 2023-09-11 公開日 2024-03-27 最終更新日 2024-06-26 実験手法 X-RAY DIFFRACTION (3.02 Å) 主引用文献 Discovery of Potent Isoindolinone Inhibitors that Target an Active Conformation of PARP1 Using DNA-Encoded Libraries. Chemmedchem, 19, 2024
8U4V	Cryo-EM structure of human claudin-4 complex with Clostridium perfringens enterotoxin C-terminal domain, sFab COP-1, and Nanobody 分子名称: Anti-fab nanobody, COP-1 sFab Heavy Chain, COP-1 sFab Light Chain, ... 著者 Vecchio, A.J. 登録日 2023-09-11 公開日 2023-10-25 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.99 Å) 主引用文献 Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment. Commun Biol, 7, 2024
8U4U	Crystal structure of 53BP1 tandem Tudor domain homodimer engineered with two disulfide bridges 分子名称: TP53-binding protein 1 著者 Cui, G, Botuyan, M.V, Thompson, J.R, Mer, G. 登録日 2023-09-11 公開日 2023-09-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.79 Å) 主引用文献 An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering. Nat Commun, 14, 2023
8U4T	Structure of tetrameric CXCR4 in complex with REGN7663 Fab 分子名称: (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, C-X-C chemokine receptor type 4, CHOLESTEROL, ... 著者 Saotome, K, McGoldrick, L.L, Franklin, M.C. 登録日 2023-09-11 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 Structural insights into CXCR4 modulation and oligomerization Biorxiv, 2024
8U4S	Structure of trimeric CXCR4 in complex with REGN7663 Fab 分子名称: (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, C-X-C chemokine receptor type 4, CHOLESTEROL, ... 著者 Saotome, K, McGoldrick, L.L, Franklin, M.C. 登録日 2023-09-11 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.35 Å) 主引用文献 Structural insights into CXCR4 modulation and oligomerization Biorxiv, 2024
8U4R	Structure of REGN7663-Fab bound CXCR4 分子名称: C-X-C chemokine receptor type 4, CHOLESTEROL, REGN7663 Fab heavy chain, ... 著者 Saotome, K, McGoldrick, L.L, Franklin, M.C. 登録日 2023-09-11 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural insights into CXCR4 modulation and oligomerization Biorxiv, 2024

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