PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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7H05	Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0008287-001 分子名称: N-[(1S)-2-methyl-1-(1-methyl-1H-pyrazol-4-yl)propyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Papain-like protease nsp3 著者 Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. 登録日 2024-01-23 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
5JR7	Crystal structure of an ACRDYS heterodimer [RIa(92-365):C] of PKA 分子名称: ADENOSINE-5'-DIPHOSPHATE, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type I-alpha regulatory subunit 著者 Bruystens, J.G.H, Wu, J, Taylor, S.S. 登録日 2016-05-05 公開日 2017-03-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.56 Å) 主引用文献 Structure of a PKA RI alpha Recurrent Acrodysostosis Mutant Explains Defective cAMP-Dependent Activation. J. Mol. Biol., 428, 2016
2LT1	Solution NMR structure of the 72-residue N-terminal domain of Myxococcus xanthus CarD 分子名称: CarD protein 著者 Jimenez, M.A, Padmanabhan, S. 登録日 2012-05-10 公開日 2013-11-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure-Function Dissection of Myxococcus xanthus CarD N-Terminal Domain, a Defining Member of the CarD_CdnL_TRCF Family of RNA Polymerase Interacting Proteins. Plos One, 10
2I14	Crystal structure of nicotinate-nucleotide pyrophosphorylase from Pyrococcus furiosus 分子名称: 1-ALPHA-PYROPHOSPHORYL-2-ALPHA,3-ALPHA-DIHYDROXY-4-BETA-CYCLOPENTANE-METHANOL-5-PHOSPHATE, Nicotinate-nucleotide pyrophosphorylase, ZINC ION 著者 Shin, D.H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) 登録日 2006-08-12 公開日 2006-10-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of nicotinate-nucleotide pyrophosphorylase from Pyrococcus furiosus To be Published
7A0M	TSC1 N-terminal domain 分子名称: SULFATE ION, TSC1 N-terminal domain 著者 Zech, R, Kiontke, S, Kuemmel, D. 登録日 2020-08-10 公開日 2021-05-26 最終更新日 2021-07-14 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation. Mol.Cell, 81, 2021
7H08	Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0012346-001 分子名称: 4-{[(1S)-1-(1,1-dioxo-1,2,3,4-tetrahydro-1lambda~6~-benzothiopyran-7-yl)-2-methylpropyl]amino}-N-methyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide, Papain-like protease nsp3 著者 Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. 登録日 2024-01-23 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
5JZT	Cryo-EM structure of aerolysin pore in LMNG micelle 分子名称: Aerolysin 著者 Iacovache, I, Zuber, B. 登録日 2016-05-17 公開日 2016-07-13 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 Cryo-EM structure of aerolysin variants reveals a novel protein fold and the pore-formation process. Nat Commun, 7, 2016
2YMO	Crystal structure of Pf12 tandem 6-cys domains from Plasmodium falciparum 分子名称: PF12 著者 Tonkin, M.L, Arredondo, S.A, Loveless, B.C, Grigg, M.E, Miller, L.H, Boulanger, M.J. 登録日 2012-10-09 公開日 2013-03-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and Biochemical Characterization of Plasmodium Falciparum 12 (Pf12) Reveals a Unique Inter-Domain Organization and the Potential for an Antiparallel Arrangement with Pf41 J.Biol.Chem., 288, 2013
5K0H	Human factor Xa in complex with synthetic inhibitor benzylsulfonyl-dSer(Benzyl)-Gly-4-amidinobenzylamide 分子名称: CALCIUM ION, Coagulation factor X, O-benzyl-N-(benzylsulfonyl)-D-seryl-N-[(4-carbamimidoylphenyl)methyl]glycinamide 著者 Steinmetzer, T. 登録日 2016-05-17 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 New substrate analogue inhibitors of factor Xa containing 4-amidinobenzylamide as P1 residue: part 1. Medicinal Chemistry, 2, 2006
8P3S	Homomeric GluA2 flip R/G-unedited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 2 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Glutamate receptor 2, ... 著者 Zhang, D, Krieger, J.M, Yamashita, K, Greger, I. 登録日 2023-05-18 公開日 2023-08-30 最終更新日 2023-10-11 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor. Nature, 621, 2023
7H06	Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0010739-001 分子名称: 7-{(1S)-1-[(6-amino-5-chloropyrimidin-4-yl)amino]-2-methylpropyl}-3,4-dihydro-1lambda~6~-benzothiopyran-1,1(2H)-dione, Papain-like protease nsp3 著者 Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. 登録日 2024-01-23 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
2LBG	Structure of the CHR of the Prion protein in DPC Micelles 分子名称: Major prion protein 著者 Sauve, S, Aubin, Y. 登録日 2011-03-31 公開日 2011-12-07 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Interactions between the Conserved Hydrophobic Region of the Prion Protein and Dodecylphosphocholine Micelles. J.Biol.Chem., 287, 2012
7D5N	Crystal structure of inositol dehydrogenase homolog complexed with NADH and myo-inositol from Azotobacter vinelandii 分子名称: 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Oxidoreductase 著者 Fukano, K, Ono, T, Suzuki, M, Takenoya, M, Ito, S, Sasaki, Y, Yajima, S. 登録日 2020-09-27 公開日 2021-09-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of inositol dehydrogenase complexed with NADH and myo-inositol from Azotobacter vinelandii To Be Published
7H0N	Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0011215-001 分子名称: 7-[(1R)-1-({(6M)-6-[(4R)-imidazo[1,5-a]pyridin-6-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)-2-methylpropyl]-3,4-dihydro-1lambda~6~-benzothiopyran-1,1(2H)-dione, Papain-like protease nsp3 著者 Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. 登録日 2024-01-23 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
6ZTK	Crystal structure of Mialostatin, a gut cystatin from the hard tick Ixodes ricinus 分子名称: FRAGMENT OF TRITON X-100, Mialostatin, SULFATE ION 著者 Busa, M, Rezacova, P, Mares, M. 登録日 2020-07-20 公開日 2021-06-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Mialostatin, a Novel Midgut Cystatin from Ixodes ricinus Ticks: Crystal Structure and Regulation of Host Blood Digestion. Int J Mol Sci, 22, 2021
3GJN	Following evolutionary paths to high affinity and selectivity protein-protein interactions using Colicin7 and Immunity proteins 分子名称: Colicin-E7, Colicin-E9 immunity protein, ZINC ION 著者 Dym, O, Tawfik, D.S. 登録日 2009-03-09 公開日 2009-09-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Following evolutionary paths to protein-protein interactions with high affinity and selectivity Nat.Struct.Mol.Biol., 16, 2009
7PEL	CryoEM structure of simian T-cell lymphotropic virus intasome in complex with PP2A regulatory subunit B56 gamma 分子名称: DNA (5'-D(*AP*CP*TP*GP*TP*GP*TP*TP*TP*GP*GP*CP*GP*CP*TP*TP*CP*TP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*AP*GP*AP*AP*GP*CP*GP*CP*CP*AP*AP*AP*CP*AP*CP*A)-3'), Isoform 3 of PC4 and SFRS1-interacting protein,Isoform Gamma-2 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ... 著者 Barski, M, Pye, V.E, Nans, A, Cherepanov, P, Maertens, G.N. 登録日 2021-08-10 公開日 2021-08-25 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.34 Å) 主引用文献 Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56gamma. Nat Commun, 11, 2020
2I57	Crystal Structure of L-Rhamnose Isomerase from Pseudomonas stutzeri in Complex with D-Allose 分子名称: D-ALLOSE, L-rhamnose isomerase, ZINC ION 著者 Yoshida, H, Yamada, M, Takada, G, Izumori, K, Kamitori, S. 登録日 2006-08-24 公開日 2006-12-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 The Structures of l-Rhamnose Isomerase from Pseudomonas stutzeri in Complexes with l-Rhamnose and d-Allose Provide Insights into Broad Substrate Specificity J.Mol.Biol., 365, 2007
7CZE	Crystal structure of Epstein-Barr virus (EBV) gHgL and in complex with the ligand binding domian (LBD) of EphA2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ... 著者 Su, C, Wu, L.L, Song, H, Chai, Y, Qi, J.X, Yan, J.H, Gao, G.F. 登録日 2020-09-08 公開日 2020-10-21 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Molecular basis of EphA2 recognition by gHgL from gammaherpesviruses. Nat Commun, 11, 2020
7DG7	DPBB domain of VCP-like ATPase from Methanopyrus kandleri 分子名称: ATPase of the AAA+ class, IMIDAZOLE, ZINC ION 著者 Yagi, S, Tagami, S. 登録日 2020-11-11 公開日 2021-09-29 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.604 Å) 主引用文献 Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase. J.Am.Chem.Soc., 143, 2021
7DG9	DPBB domain of VCP-like ATPase from Aeropyrum pernix 分子名称: Cell division control protein 48, AAA family, ZINC ION 著者 Yagi, S, Tagami, S. 登録日 2020-11-11 公開日 2021-09-29 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.602 Å) 主引用文献 Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase. J.Am.Chem.Soc., 143, 2021
7RUP	Structure of the human GIGYF2-TNRC6A complex 分子名称: GRB10-interacting GYF protein 2, SULFATE ION, Trinucleotide repeat-containing gene 6A protein 著者 Sobti, M, Mead, B.J, Igreja, C, Stewart, A.G, Christie, M. 登録日 2021-08-18 公開日 2022-08-24 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Molecular basis for GIGYF-TNRC6 complex assembly. Rna, 29, 2023
7A3V	tRNA-guanine transglycosylase C158S/C281S/Y330C/H333A mutant in complex with 3-hydroxysulfolane 分子名称: 1,2-ETHANEDIOL, 3-hydroxythietane-1,1-dioxide, GLYCEROL, ... 著者 Nguyen, D, Heine, A, Klebe, G. 登録日 2020-08-18 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Targeting a Cryptic Pocket in a Protein-Protein Contact by Disulfide-Induced Rupture of a Homodimeric Interface. Acs Chem.Biol., 16, 2021
7SFM	Mycobacterium tuberculosis Hip1 crystal structure 分子名称: ACETATE ION, GLYCEROL, Hip1 著者 Ostrov, D.A, Li, D. 登録日 2021-10-04 公開日 2022-08-24 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.149 Å) 主引用文献 2.1 angstrom crystal structure of the Mycobacterium tuberculosis serine hydrolase, Hip1, in its anhydro-form (Anhydrohip1). Biochem.Biophys.Res.Commun., 630, 2022
7A1D	Cryo-EM map of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis (open conformation) 分子名称: NAD-specific glutamate dehydrogenase 著者 Lazaro, M, Melero, R, Huet, C, Lopez-Alonso, J.P, Delgado, S, Dodu, A, Bruch, E.M, Abriata, L.A, Alzari, P.M, Valle, M, Lisa, M.N. 登録日 2020-08-12 公開日 2021-06-09 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.19 Å) 主引用文献 3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme. Commun Biol, 4, 2021

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