7PEL

CryoEM structure of simian T-cell lymphotropic virus intasome in complex with PP2A regulatory subunit B56 gamma

Replaces:  6Z2Y

Summary for 7PEL

• Entry DOI: 10.2210/pdb7pel/pdb
• Related: 6QBT 6QBV 6QBW 6TJU 6TOQ
• EMDB information: 11052
• Descriptor: Pol protein, Isoform 3 of PC4 and SFRS1-interacting protein,Isoform Gamma-2 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, DNA (5'-D(*AP*CP*TP*GP*TP*GP*TP*TP*TP*GP*GP*CP*GP*CP*TP*TP*CP*TP*CP*TP*C)-3'), ... (5 entities in total)
• Functional Keywords: integrase, transferase, deltaretrovirus, pp2a, b56, phosphatase, molecular mimicry, host factor, dna-binding, viral protein
• Biological source: Simian T-lymphotropic virus 1; More
• Total number of polymer chains: 10
• Total formula weight: 332223.95

Authors

Barski, M.,Pye, V.E.,Nans, A.,Cherepanov, P.,Maertens, G.N. (deposition date: 2021-08-10, release date: 2021-08-25)

• Primary citation: Barski, M.S.,Minnell, J.J.,Hodakova, Z.,Pye, V.E.,Nans, A.,Cherepanov, P.,Maertens, G.N.; Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56gamma.; Nat Commun, 11:5043-, 2020; PubMed: 33028863; DOI: 10.1038/s41467-020-18874-y

Experimental method

ELECTRON MICROSCOPY (3.34 Å)