PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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4OP8	Room temperature crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying G238S mutation 分子名称: CALCIUM ION, SULFATE ION, TEM-94 ES-beta-lactamase, ... 著者 Dellus-Gur, E, Elias, M, Fraser, J.S, Tawfik, D.S. 登録日 2014-02-05 公開日 2015-05-20 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Negative Epistasis and Evolvability in TEM-1 beta-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder. J. Mol. Biol., 427, 2015
1ZTG	human alpha polyC binding protein KH1 分子名称: 5'-D(P*CP*CP*CP*TP*CP*CP*CP*T)-3', POLY(RC)-BINDING PROTEIN 1 著者 Sidiqi, M, Wilce, J.A, Barker, A, Schmidgerger, J, Leedman, P.J, Wilce, M.C.J. 登録日 2005-05-27 公開日 2006-05-27 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides Nucleic Acids Res., 40, 2012
4FMW	Crystal structure of methyltransferase domain of human RNA (guanine-9-) methyltransferase domain containing protein 2 分子名称: 1,2-ETHANEDIOL, POTASSIUM ION, RNA (guanine-9-)-methyltransferase domain-containing protein 2, ... 著者 Dong, A, Zeng, H, Loppnau, P, Tempel, W, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Wu, H, Structural Genomics Consortium (SGC) 登録日 2012-06-18 公開日 2012-08-22 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of methyltransferase domain of human RNA (guanine-9-) methyltransferase domain containing protein 2 TO BE PUBLISHED
3EFQ	T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-714 分子名称: 1-(2,2-diphosphonoethyl)-3-(octyloxy)pyridinium, Farnesyl pyrophosphate synthase, MAGNESIUM ION 著者 Cao, R, Gao, Y, Robinson, H, Oldfield, E. 登録日 2008-09-09 公開日 2009-05-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation. J.Am.Chem.Soc., 131, 2009
4FOV	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 3-Cyclohexyl-1-propylsulfonic acid 分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, DIMETHYL SULFOXIDE, Sialidase B 著者 Brear, P. 登録日 2012-06-21 公開日 2012-10-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
6D1I	Crystal structure of NDM-1 complexed with compound 12 分子名称: ACETATE ION, Metallo-beta-lactamase type 2, ZINC ION, ... 著者 Pemberton, O.A, Chen, Y. 登録日 2018-04-11 公開日 2019-04-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases. J.Med.Chem., 62, 2019
1TON	RAT SUBMAXILLARY GLAND SERINE PROTEASE, TONIN. STRUCTURE SOLUTION AND REFINEMENT AT 1.8 ANGSTROMS RESOLUTION 分子名称: TONIN, ZINC ION 著者 Fujinaga, M, James, M.N.G. 登録日 1987-06-03 公開日 1988-01-16 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Rat submaxillary gland serine protease, tonin. Structure solution and refinement at 1.8 A resolution. J.Mol.Biol., 195, 1987
2VU7	Atomic resolution (1.08 A) structure of purified thaumatin I grown in sodium meso-tartrate at 4 C 分子名称: 1,2-ETHANEDIOL, S,R MESO-TARTARIC ACID, Thaumatin-1 著者 Jakoncic, J, Asherie, N, Ginsberg, C. 登録日 2008-05-21 公開日 2009-07-14 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.08 Å) 主引用文献 Tartrate Chirality Determines Thaumatin Crystal Habit Cryst.Growth Des., 9, 2009
4RH3	AMPPCP-bound structure of human platelet phosphofructokinase in an R-state, crystal form II 分子名称: ATP-dependent 6-phosphofructokinase, platelet type, PHOSPHATE ION, ... 著者 Kloos, M. 登録日 2014-10-01 公開日 2015-06-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.02 Å) 主引用文献 Crystal structure of human platelet phosphofructokinase-1 locked in an activated conformation. Biochem.J., 469, 2015
1Q8F	Crystal Structure of the E.coli pyrimidine nucleoside hydrolase yeiK 分子名称: CALCIUM ION, GLYCEROL, Pyrimidine nucleoside hydrolase 著者 Giabbai, B, Degano, M. 登録日 2003-08-21 公開日 2004-05-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure to 1.7 a of the Escherichia coli pyrimidine nucleoside hydrolase YeiK, a novel candidate for cancer gene therapy. STRUCTURE, 12, 2004
4FGF	REFINEMENT OF THE STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION AND ANALYSIS OF PRESUMED HEPARIN BINDING SITES BY SELENATE SUBSTITUTION 分子名称: BASIC FIBROBLAST GROWTH FACTOR, BETA-MERCAPTOETHANOL, SULFATE ION 著者 Eriksson, A.E, Matthews, B.W. 登録日 1993-02-26 公開日 1993-07-15 最終更新日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Refinement of the structure of human basic fibroblast growth factor at 1.6 A resolution and analysis of presumed heparin binding sites by selenate substitution. Protein Sci., 2, 1993
1MCV	Crystal Structure Analysis of a Hybrid Squash Inhibitor in Complex with Porcine Pancreatic Elastase 分子名称: CALCIUM ION, Elastase 1, HEI-TOE I, ... 著者 Ay, J, Hilpert, K, Krauss, N, Schneider-Mergener, J, Hoehne, W. 登録日 2002-08-06 公開日 2003-02-04 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of a hybrid squash inhibitor in complex with porcine pancreatic elastase at 1.8 A resolution. Acta Crystallogr.,Sect.D, 59, 2003
3ENE	Complex of PI3K gamma with an inhibitor 分子名称: 1-methyl-3-naphthalen-2-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 著者 Apsel, B, Blair, J.A, Gonzalez, B.Z, Nazif, T.M, Feldman, M.E, Williams, R.L, Shokat, K.M, Knight, Z.A. 登録日 2008-09-25 公開日 2008-10-14 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases Nat.Chem.Biol., 4, 2008
4C1S	Glycoside hydrolase family 76 (mannosidase) Bt3792 from Bacteroides thetaiotaomicron VPI-5482 分子名称: 1,2-ETHANEDIOL, GLYCEROL, GLYCOSIDE HYDROLASE FAMILY 76 MANNOSIDASE 著者 Cuskin, F, Lowe, E.C, Zhu, Y, Temple, M, Thompson, A.J, Cartmell, A, Piens, K, Bracke, D, Vervecken, W, Munoz-Munoz, J.L, Suits, M.D.L, Boraston, A.B, Williams, S.J, Davies, G.J, Abbott, W.D, Martens, E.C, Gilbert, H.J. 登録日 2013-08-13 公開日 2013-11-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Human Gut Bacteroidetes Can Utilize Yeast Mannan Through a Selfish Mechanism. Nature, 517, 2015
3QNI	Crystal structure of human PACSIN 1 F-BAR domain 分子名称: CALCIUM ION, Protein kinase C and casein kinase substrate in neurons protein 1 著者 Meng, G, Bai, X, Zheng, X. 登録日 2011-02-08 公開日 2011-08-10 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of human PACSIN 1 F-BAR domain to be published
7JNR	Carbonic Anhydrase II Complexed with N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)propionamide 分子名称: Carbonic anhydrase 2, GLYCEROL, N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)propanamide, ... 著者 Andring, J.T, McKenna, R. 登録日 2020-08-05 公開日 2020-11-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.443 Å) 主引用文献 Structural Basis of Nanomolar Inhibition of Tumor-Associated Carbonic Anhydrase IX: X-Ray Crystallographic and Inhibition Study of Lipophilic Inhibitors with Acetazolamide Backbone. J.Med.Chem., 63, 2020
3Q90	Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1 分子名称: Ras GTPase-activating protein-binding protein 1 著者 Welin, M, Tresaugues, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Ekblad, T, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Kouznetsova, E, Moche, M, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Thorsell, A.G, Van Der Berg, S, Wahlberg, E, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC) 登録日 2011-01-07 公開日 2011-02-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1 To be Published
4CDK	Structure of ZNRF3-RSPO1 分子名称: E3 UBIQUITIN-PROTEIN LIGASE ZNRF3, R-SPONDIN-1 著者 Peng, W.C, de Lau, W, Madoori, P.K, Forneris, F, Granneman, J.C.M, Clevers, H, Gros, P. 登録日 2013-11-01 公開日 2014-01-08 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structures of Wnt-Antagonist Znrf3 and its Complex with R-Spondin 1 and Implications for Signaling. Plos One, 8, 2013
3QA2	X-ray Structure of ketohexokinase in complex with a pyrimidopyrimidine analog 2 分子名称: Ketohexokinase, N~8~-(cyclopropylmethyl)-N~4~-(2-methylphenyl)-2-(piperazin-1-yl)pyrimido[5,4-d]pyrimidine-4,8-diamine, SULFATE ION 著者 Abad, M.C. 登録日 2011-01-10 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.519 Å) 主引用文献 Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site. ACS Med Chem Lett, 2, 2011
4N5V	Alternative substrates of Mycobacterium tuberculosis anthranilate phosphoribosyl transferase 分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-amino-4-fluorobenzoic acid, Anthranilate phosphoribosyltransferase, ... 著者 Castell, A, Cookson, T.V.M, Parker, E.J, Baker, E.N, Lott, J.S. 登録日 2013-10-10 公開日 2014-04-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis. Biochem.J., 461, 2014
4MSD	Crystal structure of Schizosaccharomyces pombe AMSH-like protein SST2 T319I mutant 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, AMSH-like protease sst2, ... 著者 Shrestha, R.K, Ronau, J.A, Das, C. 登録日 2013-09-18 公開日 2014-06-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product. Biochemistry, 53, 2014
1MTW	FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN 分子名称: (2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-[4-({(3R)-1-[(1Z)-ethanimidoyl]pyrrolidin-3-yl}oxy)phenyl]propanoic acid, CALCIUM ION, TRYPSIN 著者 Stubbs, M.T. 登録日 1997-05-16 公開日 1997-11-12 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin. FEBS Lett., 375, 1995
3BSH	Barley alpha-amylase isozyme 1 (AMY1) double mutant Y105A/Y380A in complex with inhibitor acarbose 分子名称: Alpha-amylase type A isozyme, CALCIUM ION, beta-D-glucopyranose 著者 Aghajari, N, Robert, X, Haser, R. 登録日 2007-12-24 公開日 2008-08-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Multi-site substrate binding and interplay in barley alpha-amylase 1 Febs Lett., 582, 2008
4MUI	Crystal structure of pantothenate synthetase in complex with 2-(5-methoxy-2-(4-methoxyphenylsulfonylcarbamoyl)-1H-indol-1-yl)acetic acid 分子名称: (5-methoxy-2-{[(4-methoxyphenyl)sulfonyl]carbamoyl}-1H-indol-1-yl)acetic acid, 1,2-ETHANEDIOL, ETHANOL, ... 著者 Silvestre, H.L, Blundell, T.L. 登録日 2013-09-22 公開日 2014-08-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Optimization of Inhibitors of Mycobacterium tuberculosis Pantothenate Synthetase Based on Group Efficiency Analysis. Chemmedchem, 11, 2016
2GQI	Solution structure of the SH3 domain of human Ras GTPase-activating protein 1 分子名称: Ras GTPase-activating protein 1 著者 Kurosaki, C, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-21 公開日 2006-10-21 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the SH3 domain of human Ras GTPase-activating protein 1 To be Published

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