3D70
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5Y50
| Crystal structure of eukaryotic MATE transporter AtDTX14 | 分子名称: | Protein DETOXIFICATION 14 | 著者 | Miyauchi, H, Kusakizako, T, Nishizawa, T, Ishitani, R, Nureki, O. | 登録日 | 2017-08-06 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for xenobiotic extrusion by eukaryotic MATE transporter Nat Commun, 8, 2017
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1JT0
| Crystal structure of a cooperative QacR-DNA complex | 分子名称: | HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, QACA operator, SULFATE ION | 著者 | Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G. | 登録日 | 2001-08-20 | 公開日 | 2002-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR. EMBO J., 21, 2002
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7OZ1
| Cryo-EM structure of ABCG1 E242Q mutant with ATP and cholesteryl hemisuccinate bound | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Skarda, L, Kowal, J, Locher, K.P. | 登録日 | 2021-06-25 | 公開日 | 2021-09-22 | 最終更新日 | 2021-09-29 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structure of the Human Cholesterol Transporter ABCG1. J.Mol.Biol., 433, 2021
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7DQK
| A nicotine MATE transporter, Nicotiana tabacum MATE2 (NtMATE2) | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Tanaka, Y, Tsukazaki, T, Sasaki, A, Iwaki, S. | 登録日 | 2020-12-24 | 公開日 | 2021-06-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal structures of a nicotine MATE transporter provide insight into its mechanism of substrate transport. Febs Lett., 595, 2021
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3F8F
| Crystal structure of multidrug binding transcriptional regulator LmrR complexed with Daunomycin | 分子名称: | DAUNOMYCIN, Transcriptional regulator, PadR-like family | 著者 | Madoori, P.K, Agustiandari, H, Driessen, A.J.M, Thunnissen, A.-M.W.H. | 登録日 | 2008-11-12 | 公開日 | 2008-12-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition. Embo J., 28, 2009
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3F8C
| Crystal structure of multidrug binding transcriptional regulator LmrR complexed with Hoechst 33342 | 分子名称: | 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, Transcriptional regulator, PadR-like family | 著者 | Madoori, P.K, Agustiandari, H, Driessen, A.J.M, Thunnissen, A.-M.W.H. | 登録日 | 2008-11-12 | 公開日 | 2008-12-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition. Embo J., 28, 2009
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3F8B
| Crystal structure of the multidrug binding transcriptional regulator LmrR in drug free state | 分子名称: | Transcriptional regulator, PadR-like family | 著者 | Madoori, P.K, Agustiandari, H, Driessen, A.J.M, Thunnissen, A.-M.W.H. | 登録日 | 2008-11-12 | 公開日 | 2008-12-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition. Embo J., 28, 2009
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3Q2Y
| Crystal Structure of BmrR bound to ethidium | 分子名称: | 23 bp promoter, ETHIDIUM, GLYCEROL, ... | 著者 | Bachas, S, Eginton, C, Gunio, G, Wade, H. | 登録日 | 2010-12-20 | 公開日 | 2011-06-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proc.Natl.Acad.Sci.USA, 108, 2011
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3Q5R
| Crystal structure of BmrR bound to Kanamycin | 分子名称: | 23 bp promoter DNA, KANAMYCIN A, Multidrug-efflux transporter 1 regulator | 著者 | Bachas, S, Eginton, C, Gunio, G, Wade, H. | 登録日 | 2010-12-29 | 公開日 | 2011-07-20 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proc.Natl.Acad.Sci.USA, 108, 2011
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3Q5P
| Crystal structure of BmrR bound to Tetracycline | 分子名称: | 23 bp BmrR promoter DNA, GLYCEROL, Multidrug-efflux transporter 1 regulator, ... | 著者 | Bachas, S, Eginton, C, Gunio, G, Wade, H. | 登録日 | 2010-12-29 | 公開日 | 2011-06-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.942 Å) | 主引用文献 | Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proc.Natl.Acad.Sci.USA, 108, 2011
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3Q5S
| Crystal structure of BmrR bound to Acetylcholine | 分子名称: | 23 bp promoter DNA, ACETYLCHOLINE, GLYCEROL, ... | 著者 | Bachas, S, Eginton, C, Gunio, G, Wade, H. | 登録日 | 2010-12-29 | 公開日 | 2011-06-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proc.Natl.Acad.Sci.USA, 108, 2011
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3Q1M
| Crystal Structure of BmrR Dimer bound to DNA and the ligand 4-amino-quinaldine | 分子名称: | 2-methylquinolin-4-amine, 23 bp promoter DNA, Multidrug-efflux transporter 1 regulator | 著者 | Bachas, S, Eginton, C, Gunio, G, Wade, H. | 登録日 | 2010-12-17 | 公開日 | 2011-06-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proc.Natl.Acad.Sci.USA, 108, 2011
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3Q3D
| Crystal structure of BmrR bound to puromycin | 分子名称: | BmrR promoter DNA, Multidrug-efflux transporter 1 regulator, PUROMYCIN | 著者 | Bachas, S, Eginton, C, Gunio, G, Wade, H. | 登録日 | 2010-12-21 | 公開日 | 2011-06-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proc.Natl.Acad.Sci.USA, 108, 2011
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5ENS
| Rhodamine bound structure of bacterial efflux pump. | 分子名称: | DARPin, Multidrug efflux pump subunit AcrB,Multidrug efflux pump subunit AcrB, RHODAMINE 6G | 著者 | Sjuts, H, Ornik, A.R, Pos, K.M. | 登録日 | 2015-11-09 | 公開日 | 2016-04-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives. Proc.Natl.Acad.Sci.USA, 113, 2016
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5ENO
| MBX2319 bound structure of bacterial efflux pump. | 分子名称: | 3,3-dimethyl-8-morpholin-4-yl-6-(2-phenylethylsulfanyl)-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile, DARPin, Multidrug efflux pump subunit AcrB,Multidrug efflux pump subunit AcrB | 著者 | Sjuts, H, Ornik, A.R, Pos, K.M. | 登録日 | 2015-11-09 | 公開日 | 2016-04-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives. Proc.Natl.Acad.Sci.USA, 113, 2016
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5EN5
| Apo structure of bacterial efflux pump. | 分子名称: | DARPin, Multidrug efflux pump subunit AcrB,Multidrug efflux pump subunit AcrB | 著者 | Sjuts, H, Ornik, A.R, Pos, K.M. | 登録日 | 2015-11-09 | 公開日 | 2016-04-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives. Proc.Natl.Acad.Sci.USA, 113, 2016
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5ENP
| MBX2931 bound structure of bacterial efflux pump. | 分子名称: | 6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile, DARPin, Multidrug efflux pump subunit AcrB,Multidrug efflux pump subunit AcrB | 著者 | Sjuts, H, Ornik, A.R, Pos, K.M. | 登録日 | 2015-11-09 | 公開日 | 2016-04-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives. Proc.Natl.Acad.Sci.USA, 113, 2016
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5ENR
| MBX3135 bound structure of bacterial efflux pump. | 分子名称: | DARPin, Multidrug efflux pump subunit AcrB,Multidrug efflux pump subunit AcrB, ~{N}-[4-[2-[[5-cyano-8-[(2~{S},6~{S})-2,6-dimethylmorpholin-4-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridin-6-yl]sulfanyl]ethyl]phenyl]prop-2-enamide | 著者 | Sjuts, H, Ornik, A.R, Pos, K.M. | 登録日 | 2015-11-09 | 公開日 | 2016-04-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives. Proc.Natl.Acad.Sci.USA, 113, 2016
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5ENQ
| MBX3132 bound structure of bacterial efflux pump. | 分子名称: | DARPin, Multidrug efflux pump subunit AcrB,Multidrug efflux pump subunit AcrB, ~{N}-[4-[2-[[5-cyano-8-[(2~{S},6~{R})-2,6-dimethylmorpholin-4-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridin-6-yl]sulfanyl]ethyl]phenyl]ethanamide | 著者 | Sjuts, H, Ornik, A.R, Pos, K.M. | 登録日 | 2015-11-09 | 公開日 | 2016-04-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives. Proc.Natl.Acad.Sci.USA, 113, 2016
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5ENT
| Minocycline bound structure of bacterial efflux pump. | 分子名称: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, DARPin, DI(HYDROXYETHYL)ETHER, ... | 著者 | Sjuts, H, Ornik, A.R, Pos, K.M. | 登録日 | 2015-11-09 | 公開日 | 2016-04-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives. Proc.Natl.Acad.Sci.USA, 113, 2016
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5KHS
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5AZP
| Crystal structure of a membrane protein from Pseudomonas aeruginosa | 分子名称: | (2S)-1-(pentanoyloxy)propan-2-yl hexanoate, ACETATE ION, FORMIC ACID, ... | 著者 | Yonehara, R, Yamashita, E, Nakagawa, A. | 登録日 | 2015-10-21 | 公開日 | 2016-06-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Crystal structures of OprN and OprJ, outer membrane factors of multidrug tripartite efflux pumps of Pseudomonas aeruginosa. Proteins, 84, 2016
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1QVU
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1QVT
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