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8V6M
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Inactivated-state cryo-EM structure of human TRPV3 in presence of tetrahydrocannabivarin (THCV) in cNW30 nanodiscs
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Tetrahydrocannabivarin, ...
著者Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
登録日2023-12-01
公開日2024-04-17
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.63 Å)
主引用文献TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site.
Sci Adv, 10, 2024
5OEO
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Solution structure of the complex of TRPV5(655-725) with a Calmodulin E32Q/E68Q double mutant
分子名称: CALCIUM ION, Calmodulin-1, Transient receptor potential cation channel subfamily V member 5
著者Vuister, G.W, Bokhovchuk, F.M, Bate, N, Kovalevskaya, N, Goult, B.T, Spronk, C.A.E.M.
登録日2017-07-09
公開日2018-04-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Structural Basis of Calcium-Dependent Inactivation of the Transient Receptor Potential Vanilloid 5 Channel.
Biochemistry, 57, 2018
6MHX
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BU of 6mhx by Molmil
Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (2)
分子名称: Transient receptor potential cation channel subfamily V member 3
著者Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y.
登録日2018-09-18
公開日2018-10-03
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6MHW
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BU of 6mhw by Molmil
Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (1)
分子名称: Transient receptor potential cation channel subfamily V member 3
著者Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y.
登録日2018-09-18
公開日2018-10-03
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6MHV
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Structure of human TRPV3 in the presence of 2-APB in C4 symmetry
分子名称: Transient receptor potential cation channel subfamily V member 3
著者Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y.
登録日2018-09-18
公開日2018-10-03
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
5WO9
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BU of 5wo9 by Molmil
Crystal Structure of Transient Receptor Potential (TRP) channel TRPV6* in the presence of Calcium
分子名称: 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
著者Singh, A.K, Saotome, K, Sobolevsky, A.I.
登録日2017-08-01
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Swapping of transmembrane domains in the epithelial calcium channel TRPV6.
Sci Rep, 7, 2017
5WO8
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Crystal Structure of Transient Receptor Potential (TRP) channel TRPV6*-Del1
分子名称: 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
著者Singh, A.K, Saotome, K, Sobolevsky, A.I.
登録日2017-08-01
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Swapping of transmembrane domains in the epithelial calcium channel TRPV6.
Sci Rep, 7, 2017
7CQH
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Complex of TRP_CBS2 and Calmodulin_Clobe
分子名称: AT15141p, CALCIUM ION, Transient receptor potential protein
著者Shen, Z.S.
登録日2020-08-10
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Calmodulin binds to Drosophila TRP with an unexpected mode.
Structure, 29, 2021
7CQV
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Complex of TRP_CBS1 and Calmodulin_Nlobe
分子名称: AT15141p, CALCIUM ION, Transient receptor potential protein
著者Shen, Z.S.
登録日2020-08-11
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Calmodulin binds to Drosophila TRP with an unexpected mode.
Structure, 29, 2021
5WO7
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BU of 5wo7 by Molmil
Crystal Structure of Transient Receptor Potential (TRP) channel TRPV6*
分子名称: 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
著者Singh, A.K, Saotome, K, Sobolevsky, A.I.
登録日2017-08-01
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.246 Å)
主引用文献Swapping of transmembrane domains in the epithelial calcium channel TRPV6.
Sci Rep, 7, 2017
6BBJ
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BU of 6bbj by Molmil
Xenopus Tropicalis TRPV4
分子名称: Transient receptor potential cation channel, subfamily V, member 4
著者Deng, Z, Hite, R.K, Yuan, P.
登録日2017-10-18
公開日2018-02-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms.
Nat. Struct. Mol. Biol., 25, 2018
5WO6
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Crystal Structure of Transient Receptor Potential (TRP) channel TRPV6cryst
分子名称: 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
著者Singh, A.K, Saotome, K, Sobolevsky, A.I.
登録日2017-08-01
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献Swapping of transmembrane domains in the epithelial calcium channel TRPV6.
Sci Rep, 7, 2017
5WOA
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BU of 5woa by Molmil
Crystal Structure of Transient Receptor Potential (TRP) channel TRPV6* in the presence of Gadolinium
分子名称: GADOLINIUM ATOM, Transient receptor potential cation channel subfamily V member 6
著者Singh, A.K, Saotome, K, Sobolevsky, A.I.
登録日2017-08-01
公開日2017-10-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.899 Å)
主引用文献Swapping of transmembrane domains in the epithelial calcium channel TRPV6.
Sci Rep, 7, 2017
7XEM
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BU of 7xem by Molmil
Cholesterol bound state of mTRPV2
分子名称: CHOLESTEROL, Transient receptor potential cation channel subfamily V member 2
著者Su, N.
登録日2022-03-31
公開日2022-08-17
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands.
Nat.Chem.Biol., 19, 2023
7XEO
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BU of 7xeo by Molmil
MbetaCD treated state of mTRPV2
分子名称: Transient receptor potential cation channel subfamily V member 2
著者Su, N.
登録日2022-03-31
公開日2022-08-17
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands.
Nat.Chem.Biol., 19, 2023
7XEV
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BU of 7xev by Molmil
Structure of mTRPV2_2-APB
分子名称: 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 2
著者Su, N.
登録日2022-03-31
公開日2022-08-17
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands.
Nat.Chem.Biol., 19, 2023
7XEU
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BU of 7xeu by Molmil
Structure of mTRPV2_E2
分子名称: CHOLESTEROL, Transient receptor potential cation channel subfamily V member 2
著者Su, N.
登録日2022-03-31
公開日2022-08-17
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.77 Å)
主引用文献Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands.
Nat.Chem.Biol., 19, 2023
7XEW
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BU of 7xew by Molmil
Structure of mTRPV2_Q525F
分子名称: Transient receptor potential cation channel subfamily V member 2
著者Su, N.
登録日2022-03-31
公開日2022-08-17
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.59 Å)
主引用文献Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands.
Nat.Chem.Biol., 19, 2023
7XER
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BU of 7xer by Molmil
Structure of mTRPV2_Q525T
分子名称: CHOLESTEROL, Transient receptor potential cation channel subfamily V member 2
著者Su, N.
登録日2022-03-31
公開日2022-08-17
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.47 Å)
主引用文献Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands.
Nat.Chem.Biol., 19, 2023
6OO5
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BU of 6oo5 by Molmil
Cryo-EM structure of the C2-symmetric TRPV2/RTx complex in amphipol resolved to 4.2 A
分子名称: TRPV2, resiniferatoxin
著者Zubcevic, L, Hsu, A.L, Borgnia, M.J, Lee, S.-Y.
登録日2019-04-22
公開日2019-05-29
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
6OO3
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BU of 6oo3 by Molmil
Cryo-EM structure of the C4-symmetric TRPV2/RTx complex in amphipol resolved to 2.9 A
分子名称: TRPV2, resiniferatoxin
著者Zubcevic, L, Hsu, A.L, Borgnia, M.J, Lee, S.-Y.
登録日2019-04-22
公開日2019-05-29
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
6OO4
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Cryo-EM structure of the C2-symmetric TRPV2/RTx complex in amphipol resolved to 3.3 A
分子名称: TRPV2, resiniferatoxin
著者Zubcevic, L, Hsu, A.L, Borgnia, M.J, Lee, S.-Y.
登録日2019-04-22
公開日2019-05-29
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
6OO7
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BU of 6oo7 by Molmil
Cryo-EM structure of the C2-symmetric TRPV2/RTx complex in nanodiscs
分子名称: TRPV2, resiniferatoxin
著者Zubcevic, L, Hsu, A.L, Borgnia, M.J, Lee, S.-Y.
登録日2019-04-22
公開日2019-05-29
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
6L93
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X-ray structure of the ligand-free human TRPV1 ankyrin repeat domain
分子名称: Transient receptor potential cation channel subfamily V member 1
著者Tanaka, M, Hayakawa, K, Unno, M.
登録日2019-11-08
公開日2020-03-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (4.47 Å)
主引用文献Structure determination of the human TRPV1 ankyrin-repeat domain under nonreducing conditions.
Acta Crystallogr.,Sect.F, 76, 2020
7YEP
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2-APB bound state of mTRPV2
分子名称: 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 2
著者Su, N.
登録日2022-07-06
公開日2022-08-17
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands.
Nat.Chem.Biol., 19, 2023

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