4TS3
Wild type E. Coli purine nucleoside phosphorylase with 2 FMC molecules in active sites
Summary for 4TS3
| Entry DOI | 10.2210/pdb4ts3/pdb |
| Descriptor | Purine nucleoside phosphorylase DeoD-type, (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, ... (4 entities in total) |
| Functional Keywords | purine nucleoside phosphorylase, formycin a, transferase |
| Biological source | Escherichia coli |
| Total number of polymer chains | 6 |
| Total formula weight | 155434.11 |
| Authors | Stefanic, Z.,Bzowska, A. (deposition date: 2014-06-18, release date: 2015-07-08, Last modification date: 2018-10-31) |
| Primary citation | Stefanic, Z.,Narczyk, M.,Mikleusevic, G.,Kazazic, S.,Bzowska, A.,Luic, M. Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis. Sci Rep, 8:15427-15427, 2018 Cited by PubMed: 30337572DOI: 10.1038/s41598-018-33723-1 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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