3INY

Crystal structure of human purine nucleoside phosphorylase in complex with 7-deazaguanine

Summary for 3INY

• Entry DOI: 10.2210/pdb3iny/pdb
• Related: 1V41
• Descriptor: Purine nucleoside phosphorylase, SULFATE ION, 7-DEAZAGUANINE, ... (4 entities in total)
• Functional Keywords: 7-deazaguanine, cytoskeleton, disease mutation, glycosyltransferase, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytoskeleton (By similarity): P00491
• Total number of polymer chains: 1
• Total formula weight: 32623.20

Authors

de Azevedo Jr, W.F.,Santos, D.S.,Basso, L.A. (deposition date: 2009-08-13, release date: 2011-01-19, Last modification date: 2023-09-06)

• Primary citation: Caceres, R.A.,Timmers, L.F.,Pauli, I.,Gava, L.M.,Ducati, R.G.,Basso, L.A.,Santos, D.S.,de Azevedo, W.F.; Crystal structure and molecular dynamics studies of human purine nucleoside phosphorylase complexed with 7-deazaguanine.; J.Struct.Biol., 169:379-388, 2010; PubMed: 19932753; DOI: 10.1016/j.jsb.2009.11.010

Experimental method

X-RAY DIFFRACTION (2.75 Å)