Crystal structure of wild type E. Coli purine nucleoside phosphorylase with 6 FMC molecules

Summary for 4TS9

DescriptorPurine nucleoside phosphorylase DeoD-type, (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, ... (4 entities in total)
Functional Keywordspurine nucleoside phosphorylase, formicyn a, transferase
Biological sourceEscherichia coli
Total number of polymer chains3
Total molecular weight78293.61
Stefanic, Z.,Bzowska, A. (deposition date: 2014-06-18, release date: 2015-07-08, Last modification date: 2018-10-31)
Primary citation
Stefanic, Z.,Narczyk, M.,Mikleusevic, G.,Kazazic, S.,Bzowska, A.,Luic, M.
Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis.
Sci Rep, 8:15427-15427, 2018
PubMed: 30337572 (PDB entries with the same primary citation)
DOI: 10.1038/s41598-018-33723-1
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1764 0.6% 2.1% 4.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload