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4FFZ
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BU of 4ffz by Molmil
Crystal Structure of DENV1-E111 fab fragment bound to DENV-1 DIII (Western Pacific-74 strain).
分子名称: DENV1-E111 fab fragment (heavy chain), DENV1-E111 fab fragment (light chain), Envelope protein E
著者Austin, S.K, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-06-01
公開日2012-06-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope.
Plos Pathog., 8, 2012
6U79
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BU of 6u79 by Molmil
Solution NMR structure of 5' UTR stem loop B from West Nile Virus
分子名称: 5' UTR region stem loop
著者Sharma, S, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2019-09-01
公開日2020-08-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure of Dengue West Nile viruses stem-loop B: A key cis-acting element for flavivirus replication.
Biochem.Biophys.Res.Commun., 531, 2020
5N6O
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BU of 5n6o by Molmil
Wild type human Rac1-GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1
著者Cherfils, J, Ferrandez, Y.
登録日2017-02-15
公開日2017-12-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Allosteric inhibition of the guanine nucleotide exchange factor DOCK5 by a small molecule.
Sci Rep, 7, 2017
5CUQ
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BU of 5cuq by Molmil
Identification and characterization of novel broad spectrum inhibitors of the flavivirus methyltransferase
分子名称: N,N'-BIS(4-AMINO-2-METHYLQUINOLIN-6-YL)UREA, Nonstructural protein NS5
著者Brecher, B, Chen, H, Li, Z, Banavali, N.K, Jones, S.A, Zhang, J, Kramer, L.D, Li, H.M.
登録日2015-07-24
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.696 Å)
主引用文献Identification and Characterization of Novel Broad-Spectrum Inhibitors of the Flavivirus Methyltransferase.
Acs Infect Dis., 1, 2015
4L5F
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BU of 4l5f by Molmil
Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII
分子名称: Envelope protein, Heavy chain of E106 antibody (VH and CH1 of IgG2c), Light chain of E106 antibody (kappa)
著者Edeling, M.A, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-06-11
公開日2013-12-11
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII
To be Published
8WBF
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BU of 8wbf by Molmil
CryoEM structure of non-structural protein 1 tetramer from ZIKA virus
分子名称: Genome polyprotein
著者Jiao, H.Z, Pan, Q, Hu, H.L.
登録日2023-09-09
公開日2024-05-22
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献The step-by-step assembly mechanism of secreted flavivirus NS1 tetramer and hexamer captured at atomic resolution.
Sci Adv, 10, 2024
8WBG
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BU of 8wbg by Molmil
CryoEM structure of non-structural protein 1 tetramer from ZIKA virus
分子名称: Genome polyprotein
著者Jiao, H.Z, Pan, Q, Hu, H.L.
登録日2023-09-09
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The step-by-step assembly mechanism of secreted flavivirus NS1 tetramer and hexamer captured at atomic resolution.
Sci Adv, 10, 2024
6KBV
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BU of 6kbv by Molmil
Three-dimensional cytoplasmic membrane-bound structure of VG16KRKP-KYE28
分子名称: Heparin cofactor 2, VG16KRKP
著者Ilyas, H, Bhunia, A.
登録日2019-06-26
公開日2019-08-14
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural insights into the combinatorial effects of antimicrobial peptides reveal a role of aromatic-aromatic interactions in antibacterial synergism.
J.Biol.Chem., 294, 2019
6KBO
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BU of 6kbo by Molmil
Three-dimensional LPS bound structure of VG16KRKP-KYE28.
分子名称: Heparin cofactor 2, VG16KRKP
著者Ilyas, H, Bhunia, A.
登録日2019-06-26
公開日2019-08-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural insights into the combinatorial effects of antimicrobial peptides reveal a role of aromatic-aromatic interactions in antibacterial synergism.
J.Biol.Chem., 294, 2019
5WYE
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BU of 5wye by Molmil
Structure of gold nano particle-tagged VG16KRKP in Salmonella typhi LPS
分子名称: Au-VG16KRKP
著者Ilyas, H, Bhunia, A.
登録日2017-01-12
公開日2017-11-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Multivalent gold nanoparticle-peptide conjugates for targeting intracellular bacterial infections
Nanoscale, 9, 2017
6DFI
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BU of 6dfi by Molmil
Crystal structure of anti-Zika antibody Z021 bound to Zika virus envelope protein DIII
分子名称: Zika virus envelope protein DIII, anti-Zika antibody Z021, Heavy Chain, ...
著者Keeffe, J.R, Bjorkman, P.J.
登録日2018-05-14
公開日2018-10-24
最終更新日2018-11-14
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates.
Cell Rep, 25, 2018
1NA4
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BU of 1na4 by Molmil
The structure of immature Yellow Fever virus particle
分子名称: major envelope protein E
著者Zhang, Y, Corver, J, Chipman, P.R, Lenches, E, Zhang, W, Pletnev, S.V, Sedlak, D, Baker, T.S, Strauss, J.H, Kuhn, R.J, Rossmann, M.G.
登録日2002-11-26
公開日2003-12-09
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY
主引用文献Structures of immature flavivirus particles
EMBO J., 22, 2003
5VIG
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BU of 5vig by Molmil
Crystal structure of anti-Zika antibody Z006 bound to Zika virus envelope protein DIII
分子名称: CITRATE ANION, Fab heavy chain, Fab light chain, ...
著者Keeffe, J.R, West Jr, A.P, Gristick, H.B, Bjorkman, P.J.
登録日2017-04-16
公開日2017-05-03
最終更新日2017-05-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico.
Cell, 169, 2017
3EVE
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BU of 3eve by Molmil
Crystal structure of GpppA complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine
分子名称: GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE
著者Thompson, A.A.
登録日2008-10-13
公開日2009-01-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVF
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BU of 3evf by Molmil
Crystal structure of Me7-GpppA complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine
分子名称: P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE
著者Thompson, A.A, Geiss, B.J, Peersen, O.B.
登録日2008-10-13
公開日2009-01-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVC
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BU of 3evc by Molmil
Crystal structure of GTP complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine
分子名称: GUANOSINE-5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE
著者Thompson, A.A, Geiss, B.J, Peersen, O.B.
登録日2008-10-13
公開日2009-01-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVA
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BU of 3eva by Molmil
Crystal structure of yellow fever virus methyltransferase complexed with S-adenosyl-L-homocysteine
分子名称: RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE
著者Thompson, A.A, Geiss, B.J, Peersen, O.B.
登録日2008-10-13
公開日2009-01-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVB
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BU of 3evb by Molmil
Crystal structure of yellow fever virus methyltransferase complexed with S-adenosyl-L-homocysteine
分子名称: RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE
著者Thompson, A.A, Geiss, B.J, Peersen, O.B.
登録日2008-10-13
公開日2009-01-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
3EVD
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BU of 3evd by Molmil
Crystal structure of GTP complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine
分子名称: GUANOSINE-5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE
著者Thompson, A.A, Geiss, B.J, Peersen, O.B.
登録日2008-10-13
公開日2009-01-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
4OII
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BU of 4oii by Molmil
West Nile Virus NS1 in complex with neutralizing 22NS1 antibody Fab
分子名称: Heavy Chain of Fab fragment of 22NS1 Antibody, Light Chain of Fab fragment of 22NS1 Antibody, NON-STRUCTURAL PROTEIN NS1
著者Edeling, M.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-01-19
公開日2014-03-05
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of Flavivirus NS1 assembly and antibody recognition.
Proc.Natl.Acad.Sci.USA, 111, 2014
6LNT
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BU of 6lnt by Molmil
Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab
分子名称: Envelope protein, Fab DV62.5 heavy-chain variable region, Fab DV62.5 light-chain variable region, ...
著者Tan, T.Y, Fibriansah, G, Kostyuchenko, V.A, Ng, T.S, Lim, X.X, Lim, X.N, Shi, J, Morais, M.C, Corti, D, Lok, S.M.
登録日2020-01-02
公開日2020-02-26
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Capsid protein structure in Zika virus reveals the flavivirus assembly process.
Nat Commun, 11, 2020
2MMM
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BU of 2mmm by Molmil
Solution structure of the mature form, GK cecropin-like peptide from Ae. aegypti mosquito
分子名称: K cecropin-like peptide
著者Padilla, A, Misse, D.
登録日2014-03-16
公開日2015-01-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Aedesin: structure and antimicrobial activity against multidrug resistant bacterial strains.
Plos One, 9, 2014
5FUM
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BU of 5fum by Molmil
Mus musculus acetylcholinesterase in complex with AL200
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, 2-(biphenyl-4-yloxy)-1-[4-(4-ethylpiperazin-1-yl)piperidin-1-yl]ethanone, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ...
著者Knutsson, S, Engdahl, C, Ekstrom, F, Linusson, A.
登録日2016-01-28
公開日2016-09-21
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovery of Selective Inhibitors Targeting Acetylcholinesterase 1 from Disease-Transmitting Mosquitoes.
J.Med.Chem., 17, 2016
2IJO
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BU of 2ijo by Molmil
Crystal Structure of the West Nile virus NS2B-NS3 protease complexed with bovine pancreatic trypsin inhibitor
分子名称: Pancreatic trypsin inhibitor, Polyprotein
著者Aleshin, A.E, Shiryaev, S.A, Strongin, A.Y, Liddington, R.C.
登録日2006-09-29
公開日2007-05-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold.
Protein Sci., 16, 2007
3UQI
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BU of 3uqi by Molmil
Crystallographic structure of FKBP12 from Aedes aegypti
分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, FKBP-type peptidyl-prolyl cis-trans isomerase, SULFATE ION
著者Sreekanth, R, Saw, K.Q, Yoon, H.S.
登録日2011-11-20
公開日2012-06-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.302 Å)
主引用文献High-resolution crystal structure of FKBP12 from Aedes aegypti.
Protein Sci., 21, 2012

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