2IJO
Crystal Structure of the West Nile virus NS2B-NS3 protease complexed with bovine pancreatic trypsin inhibitor
Summary for 2IJO
Entry DOI | 10.2210/pdb2ijo/pdb |
Related | 2FOM 2FP7 2GGV |
Descriptor | Polyprotein, Pancreatic trypsin inhibitor, ... (4 entities in total) |
Functional Keywords | west nile virus, protease, aprotinin, bpti, ns2b, ns3, flavivirus, serine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | West Nile virus More |
Cellular location | Envelope protein E: Virion membrane; Multi- pass membrane protein: Q203W3 Q203W3 Secreted: P00974 |
Total number of polymer chains | 3 |
Total formula weight | 33512.57 |
Authors | Aleshin, A.E.,Shiryaev, S.A.,Strongin, A.Y.,Liddington, R.C. (deposition date: 2006-09-29, release date: 2007-05-15, Last modification date: 2023-08-30) |
Primary citation | Aleshin, A.E.,Shiryaev, S.A.,Strongin, A.Y.,Liddington, R.C. Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold. Protein Sci., 16:795-806, 2007 Cited by PubMed: 17400917DOI: 10.1110/ps.072753207 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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