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2A0X
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Structure of human purine nucleoside phosphorylase H257F mutant
分子名称: 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, Purine nucleoside phosphorylase, SULFATE ION
著者Murkin, A.S, Shi, W, Schramm, V.L.
登録日2005-06-17
公開日2006-06-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Neighboring group participation in the transition state of human purine nucleoside phosphorylase.
Biochemistry, 46, 2007
2F80
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HIV-1 Protease mutant D30N complexed with inhibitor TMC114
分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, POL POLYPROTEIN, ...
著者Kovalevsky, A.Y, Weber, I.T.
登録日2005-12-01
公開日2006-03-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Effectiveness of Nonpeptide Clinical Inhibitor TMC-114 on HIV-1 Protease with Highly Drug Resistant Mutations D30N, I50V, and L90M.
J.Med.Chem., 49, 2006
2A1M
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Crystal structure of ferrous dioxygen complex of wild-type cytochrome P450cam
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Cytochrome P450-cam, ...
著者Nagano, S, Poulos, T.L.
登録日2005-06-20
公開日2005-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallographic study on the dioxygen complex of wild-type and mutant cytochrome P450cam. Implications for the dioxygen activation mechanism
J.Biol.Chem., 280, 2005
2EUG
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI URACIL DNA GLYCOSYLASE AND ITS COMPLEXES WITH URACIL AND GLYCEROL: STRUCTURE AND GLYCOSYLASE MECHANISM REVISITED
分子名称: PROTEIN (GLYCOSYLASE), URACIL
著者Xiao, G, Tordova, M, Jagadeesh, J, Drohat, A.C, Stivers, J.T, Gilliland, G.L.
登録日1998-10-13
公開日1999-10-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: structure and glycosylase mechanism revisited.
Proteins, 35, 1999
2ABM
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Crystal Structure of Aquaporin Z Tetramer Reveals both Open and Closed Water-conducting Channels
分子名称: (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-O-octyl-beta-D-glucopyranose, ...
著者Jiang, J, Daniels, B.V, Fu, D.
登録日2005-07-15
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal Structure of AqpZ Tetramer Reveals Two Distinct Arg-189 Conformations Associated with Water Permeation through the Narrowest Constriction of the Water-conducting Channel.
J.Biol.Chem., 281, 2006
2F9U
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HCV NS3 protease domain with NS4a peptide and a ketoamide inhibitor with a P2 norborane
分子名称: 1,1-DIMETHYLETHYL [1-CYCLOHEXYL-2-[3-[[[1-[2-[[2-[[2-(DIMETHYLAMINO)-2-OXO-1-PHENYLETHYL]AMINO]-2-OXOETHYL]AMINO]-1,2-DIOXOETHYL]PENTYL]AMINO]CARBONYL]-2-AZABICYCLO[2.2.1]HEPTAN-2-YL]-2-OXOETHYL]CARBAMATE, NS3 protease/helicase', ZINC ION, ...
著者Venkatraman, S, Njoroge, F.G, Wu, W, Girijavallabhan, V, Prongay, A.J, Butkiewicz, N, Pichardo, J.
登録日2005-12-06
公開日2006-06-06
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Novel Inhibitors of Hepatitis C NS3-NS4A Serine Protease Derived from 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid.
Bioorg.Med.Chem.Lett., 16, 2006
2FCA
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The structure of BsTrmB
分子名称: POTASSIUM ION, tRNA (guanine-N(7)-)-methyltransferase
著者Zegers, I, Van Vliet, F, Bujnicki, J, Kosinski, J, Gigot, D, Droogmans, L.
登録日2005-12-12
公開日2006-08-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of Bacillus subtilis TrmB, the tRNA (m7G46) methyltransferase.
Nucleic Acids Res., 34, 2006
2FCJ
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Structure of small TOPRIM domain protein from Bacillus stearothermophilus.
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, SULFATE ION, ...
著者Rezacova, P, Chen, Y, Borek, D, Collart, F, Joachimiak, A, Otwinowski, Z, Midwest Center for Structural Genomics (MCSG)
登録日2005-12-12
公開日2006-01-24
最終更新日2012-10-24
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure and putative function of small Toprim domain-containing protein from Bacillus stearothermophilus.
Proteins, 70, 2008
2FIB
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RECOMBINANT HUMAN GAMMA-FIBRINOGEN CARBOXYL TERMINAL FRAGMENT (RESIDUES 143-411) COMPLEXED TO THE PEPTIDE GLY-PRO-ARG-PRO AT PH 6.0
分子名称: CALCIUM ION, FIBRINOGEN, GLY-PRO-ARG-PRO
著者Pratt, K.P, Cote, H.C.F, Chung, D.W, Stenkamp, R.E, Davie, E.W.
登録日1997-06-03
公開日1997-10-15
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献The primary fibrin polymerization pocket: three-dimensional structure of a 30-kDa C-terminal gamma chain fragment complexed with the peptide Gly-Pro-Arg-Pro.
Proc.Natl.Acad.Sci.USA, 94, 1997
2FJC
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Crystal structure of antigen TpF1 from Treponema pallidum
分子名称: Antigen TpF1, FE (III) ION
著者Thumiger, A, Polenghi, A, Papinutto, E, Battistutta, R, Montecucco, C, Zanotti, G.
登録日2006-01-02
公開日2006-01-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of antigen TpF1 from Treponema pallidum.
Proteins, 62, 2006
2ETV
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Crystal structure of a putative fe(iii) abc transporter (tm0189) from thermotoga maritima msb8 at 1.70 A resolution
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, NICKEL (II) ION, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2005-10-27
公開日2006-02-07
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of IRON(III) ABC transporter, periplasmic iron-binding protein, putative (tm0189) from THERMOTOGA MARITIMA at 1.70 A resolution
To be published
2EWJ
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Escherichia Coli Replication Terminator Protein (Tus) Complexed With DNA- Locked form
分子名称: 5'-D(*T*TP*AP*GP*TP*TP*AP*CP*AP*AP*CP*AP*TP*AP*CP*T)-3', 5'-D(*TP*G*AP*TP*AP*TP*GP*TP*TP*GP*TP*AP*AP*CP*TP*A)-3', DNA replication terminus site-binding protein, ...
著者Oakley, A.J, Mulcair, M.D, Schaeffer, P.M, Dixon, N.E.
登録日2005-11-03
公開日2006-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A molecular mousetrap determines polarity of termination of DNA replication in E. coli.
Cell(Cambridge,Mass.), 125, 2006
2D9X
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Solution structure of the PH domain of Oxysterol binding protein-related protein 11 from human
分子名称: Oxysterol binding protein-related protein 11
著者Li, H, Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-13
公開日2006-06-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the PH domain of Oxysterol binding protein-related protein 11 from human
To be Published
2D4Y
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Crystal structure of a 49K fragment of HAP1 (FlgK)
分子名称: Flagellar hook-associated protein 1
著者Imada, K, Matsunami, H, Samatey, A.F, Nagashima, S, Namba, K.
登録日2005-10-25
公開日2006-11-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the bacterial flagellar hook-filament junction
To be Published
2D2C
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Crystal Structure Of Cytochrome B6F Complex with DBMIB From M. Laminosus
分子名称: (7R,17E)-4-HYDROXY-N,N,N,7-TETRAMETHYL-7-[(8E)-OCTADEC-8-ENOYLOXY]-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOS-17-EN-1-AMINIUM 4-OXIDE, 2,5-DIBROMO-3-ISOPROPYL-6-METHYLBENZO-1,4-QUINONE, Apocytochrome f, ...
著者Yan, J, Kurisu, G, Cramer, W.A.
登録日2005-09-07
公開日2005-12-13
最終更新日2014-02-26
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Intraprotein transfer of the quinone analogue inhibitor 2,5-dibromo-3-methyl-6-isopropyl-p-benzoquinone in the cytochrome b6f complex
Proc.Natl.Acad.Sci.USA, 103, 2006
2D3B
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Crystal Structure of the Maize Glutamine Synthetase complexed with AMPPNP and Methionine sulfoximine
分子名称: (2S)-2-AMINO-4-(METHYLSULFONIMIDOYL)BUTANOIC ACID, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Unno, H, Uchida, T, Sugawara, H, Kurisu, G, Sugiyama, T, Yamaya, T, Sakakibara, H, Hase, T, Kusunoki, M.
登録日2005-09-26
公開日2006-07-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Atomic Structure of Plant Glutamine Synthetase: A KEY ENZYME FOR PLANT PRODUCTIVITY
J.Biol.Chem., 281, 2006
2D3A
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Crystal Structure of the Maize Glutamine Synthetase complexed with ADP and Methionine sulfoximine Phosphate
分子名称: ADENOSINE-5'-DIPHOSPHATE, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, MANGANESE (II) ION, ...
著者Unno, H, Uchida, T, Sugawara, H, Kurisu, G, Sugiyama, T, Yamaya, T, Sakakibara, H, Hase, T, Kusunoki, M.
登録日2005-09-26
公開日2006-07-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Atomic Structure of Plant Glutamine Synthetase: A KEY ENZYME FOR PLANT PRODUCTIVITY
J.Biol.Chem., 281, 2006
2D3C
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Crystal Structure of the Maize Glutamine Synthetase complexed with ADP and Phosphinothricin Phosphate
分子名称: (2S)-2-AMINO-4-[METHYL(PHOSPHONOOXY)PHOSPHORYL]BUTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
著者Unno, H, Uchida, T, Sugawara, H, Kurisu, G, Sugiyama, T, Yamaya, T, Sakakibara, H, Hase, T, Kusunoki, M.
登録日2005-09-26
公開日2006-07-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.81 Å)
主引用文献Atomic Structure of Plant Glutamine Synthetase: A KEY ENZYME FOR PLANT PRODUCTIVITY
J.Biol.Chem., 281, 2006
2FEY
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The structure of stem loop IV of Tetrahymena telomerase RNA
分子名称: stem-loop IV of Tetrahymena telomerase RNA
著者Chen, Y, Fender, J, Legassie, J.D, Jarstfer, M.B, Bryan, T.M, Varani, G.
登録日2005-12-16
公開日2006-06-27
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of stem-loop IV of Tetrahymena telomerase RNA.
Embo J., 25, 2006
2FHO
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NMR solution structure of the human spliceosomal protein complex p14-SF3b155
分子名称: spliceosomal protein SF3b155, spliceosomal protein p14
著者Kuwasako, K, Dohmae, N, Inoue, M, Shirouzu, M, Guntert, P, Seraphin, B, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-26
公開日2006-12-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献NMR solution structure of the human spliceosomal protein complex p14-SF3b155
To be Published
2FEU
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P450CAM from Pseudomonas putida reconstituted with manganic protoporphyrin IX
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Cytochrome P450-cam, ...
著者von Koenig, K, Makris, T.M, Sligar, S.G, Schlichting, I.
登録日2005-12-16
公開日2006-03-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The status of high-valent metal oxo complexes in the P450 cytochromes.
J.Inorg.Biochem., 100, 2006
2FJ0
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Crystal Structure of Juvenile Hormone Esterase from Manduca sexta, with OTFP covalently attached
分子名称: 1,1,1-TRIFLUORO-3-(OCTYLTHIO)ACETONE, Carboxylic ester hydrolase
著者Wogulis, M, Wilson, D.K.
登録日2005-12-30
公開日2006-05-23
最終更新日2015-06-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural studies of a potent insect maturation inhibitor bound to the juvenile hormone esterase of Manduca sexta.
Biochemistry, 45, 2006
2FL9
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Evolution of bacteriophage tails: Structure of T4 gene product 10
分子名称: Baseplate structural protein Gp10
著者Leiman, P.G, Shneider, M.M, Mesyanzhinov, V.V, Rossmann, M.G.
登録日2006-01-05
公開日2006-04-04
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (17 Å)
主引用文献Evolution of bacteriophage tails: structure of t4 gene product 10
J.Mol.Biol., 358, 2006
2F3B
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Mechanism of displacement of a catalytically essential loop from the active site of fructose-1,6-bisphosphatase
分子名称: 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, PHOSPHATE ION, ...
著者Iancu, C.V, Mukund, S, Choe, J.-Y, Fromm, H.J, Honzatko, R.B.
登録日2005-11-20
公開日2006-04-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mechanism of displacement of a catalytically essential loop from the active site of mammalian fructose-1,6-bisphosphatase.
Biochemistry, 52, 2013
2F5K
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Crystal structure of the chromo domain of human MRG15
分子名称: Mortality factor 4-like protein 1
著者Zhang, P, Du, J, Ding, J.
登録日2005-11-26
公開日2006-11-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of human MRG15 chromo domain and its binding to Lys36-methylated histone H3.
Nucleic Acids Res., 34, 2006

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