2F9U
HCV NS3 protease domain with NS4a peptide and a ketoamide inhibitor with a P2 norborane
Summary for 2F9U
Entry DOI | 10.2210/pdb2f9u/pdb |
Related | 1A1R 1JXP 1N1L 2A4G 2A4Q 2A4R |
Descriptor | NS3 protease/helicase', polyprotein, ZINC ION, ... (5 entities in total) |
Functional Keywords | hcv, hepatitis c protease, ns3 protease, ketoamide inhibitor, viral protein |
Biological source | Hepatitis C virus More |
Total number of polymer chains | 4 |
Total formula weight | 47861.86 |
Authors | Venkatraman, S.,Njoroge, F.G.,Wu, W.,Girijavallabhan, V.,Prongay, A.J.,Butkiewicz, N.,Pichardo, J. (deposition date: 2005-12-06, release date: 2006-06-06, Last modification date: 2024-03-13) |
Primary citation | Venkatraman, S.,Njoroge, F.G.,Wu, W.,Girijavallabhan, V.,Prongay, A.J.,Butkiewicz, N.,Pichardo, J. Novel Inhibitors of Hepatitis C NS3-NS4A Serine Protease Derived from 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid. Bioorg.Med.Chem.Lett., 16:1628-1632, 2006 Cited by PubMed: 16413182DOI: 10.1016/j.bmcl.2005.12.046 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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