2CKA
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![BU of 2cka by Molmil](/molmil-images/mine/2cka) | Solution structures of the BRK domains of the human Chromo Helicase Domain 7 and 8, reveals structural similarity with GYF domain suggesting a role in protein interaction | 分子名称: | CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 8 | 著者 | Ab, E, de Jong, R.N, Diercks, T, Xiaoyun, J, Daniels, M, Kaptein, R, Folkers, G.E. | 登録日 | 2006-04-14 | 公開日 | 2007-05-08 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structures of the Brk Domains of the Human Chromo Helicase Domain 7 and 8, Reveals Structural Similarity with Gyf Domain Suggesting a Role in Protein Interaction To be Published
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2CO0
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![BU of 2co0 by Molmil](/molmil-images/mine/2co0) | WDR5 and unmodified Histone H3 complex at 2.25 Angstrom | 分子名称: | HISTONE H3 DIMETHYL-LYSINE 4, WD-REPEAT PROTEIN 5 | 著者 | Ruthenburg, A.J, Wang, W, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L. | 登録日 | 2006-05-25 | 公開日 | 2006-07-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Histone H3 Recognition and Presentation by the Wdr5 Module of the Mll1 Complex Nat.Struct.Mol.Biol., 13, 2006
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2EGQ
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![BU of 2egq by Molmil](/molmil-images/mine/2egq) | |
4AJH
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![BU of 4ajh by Molmil](/molmil-images/mine/4ajh) | rat LDHA in complex with N-(2-methyl-1,3-benzothiazol-6-yl)-3-ureido- propanamide and 2-(4-bromophenoxy)propanedioic acid | 分子名称: | 2-(4-BROMANYLPHENOXY)PROPANEDIOIC ACID, GLYCEROL, L-LACTATE DEHYDROGENASE A CHAIN, ... | 著者 | Tucker, J.A, Brassington, C, Hassall, G, Watson, M, Ward, R, Tart, J, Davies, G, Greenwood, R, Pearson, S, Debreczeni, J. | 登録日 | 2012-02-16 | 公開日 | 2012-03-21 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
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2EOY
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![BU of 2eoy by Molmil](/molmil-images/mine/2eoy) | Solution structure of the C2H2 type zinc finger (region 557-589) of human Zinc finger protein 473 | 分子名称: | ZINC ION, Zinc finger protein 473 | 著者 | Tochio, N, Tomizawa, T, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-29 | 公開日 | 2007-10-02 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the C2H2 type zinc finger (region 557-589) of human Zinc finger protein 473 To be Published
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2EQ4
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![BU of 2eq4 by Molmil](/molmil-images/mine/2eq4) | Solution structure of the 11th C2H2 type zinc finger domain of Zinc finger protein 224 | 分子名称: | ZINC ION, Zinc finger protein 224 | 著者 | Masuda, K, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-30 | 公開日 | 2007-10-02 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the 11th C2H2 type zinc finger domain of Zinc finger protein 224 To be Published
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2E6M
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![BU of 2e6m by Molmil](/molmil-images/mine/2e6m) | structure of mouse werner exonuclease domain | 分子名称: | SULFATE ION, Werner syndrome ATP-dependent helicase homolog | 著者 | Cho, Y, Choi, J.M. | 登録日 | 2006-12-27 | 公開日 | 2007-01-16 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | probing the roles of active site residues in 3'-5' exonuclease of werner syndrome protein TO BE PUBLISHED
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2EM5
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![BU of 2em5 by Molmil](/molmil-images/mine/2em5) | Solution structure of the C2H2 type zinc finger (region 768-800) of human Zinc finger protein 95 homolog | 分子名称: | ZINC ION, Zinc finger protein 95 homolog | 著者 | Tomizawa, T, Tochio, N, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-28 | 公開日 | 2007-10-02 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the C2H2 type zinc finger (region 768-800) of human Zinc finger protein 95 homolog To be Published
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4A0V
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![BU of 4a0v by Molmil](/molmil-images/mine/4a0v) | model refined against the Symmetry-free cryo-EM map of TRiC-AMP-PNP | 分子名称: | T-COMPLEX PROTEIN 1 SUBUNIT BETA | 著者 | Cong, Y, Schroder, G.F, Meyer, A.S, Jakana, J, Ma, B, Dougherty, M.T, Schmid, M.F, Reissmann, S, Levitt, M, Ludtke, S.L, Frydman, J, Chiu, W. | 登録日 | 2011-09-13 | 公開日 | 2012-02-15 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (10.7 Å) | 主引用文献 | Symmetry-Free Cryo-Em Structures of the Chaperonin Tric Along its ATPase-Driven Conformational Cycle. Embo J., 31, 2012
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4AJ4
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![BU of 4aj4 by Molmil](/molmil-images/mine/4aj4) | rat LDHA in complex with 4-((2-allylsulfanyl-1,3-benzothizol-6-yl) amino)-4-oxo-butanoic acid | 分子名称: | 4-oxo-4-{[2-(prop-2-en-1-ylsulfanyl)-1,3-benzothiazol-6-yl]amino}butanoic acid, L-LACTATE DEHYDROGENASE A CHAIN, MALONATE ION | 著者 | Tucker, J.A, Brassington, C, Hassall, G, Vogtherr, M, Ward, R, Tart, J, Davies, G. | 登録日 | 2012-02-15 | 公開日 | 2012-03-21 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
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4A0K
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![BU of 4a0k by Molmil](/molmil-images/mine/4a0k) | STRUCTURE OF DDB1-DDB2-CUL4A-RBX1 BOUND TO A 12 BP ABASIC SITE CONTAINING DNA-DUPLEX | 分子名称: | 12 BP DNA, 12 BP THF CONTAINING DNA, CULLIN-4A, ... | 著者 | Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H. | 登録日 | 2011-09-09 | 公開日 | 2011-12-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (5.93 Å) | 主引用文献 | The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation. Cell(Cambridge,Mass.), 147, 2011
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3ZZY
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4A0B
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![BU of 4a0b by Molmil](/molmil-images/mine/4a0b) | Structure of hsDDB1-drDDB2 bound to a 16 bp CPD-duplex (pyrimidine at D-1 position) at 3.8 A resolution (CPD 4) | 分子名称: | 5'-D(*CP*CP*TP*GP*CP*TP*CP*CP*TP*TP*TP*CP*AP*CP*CP*C)-3', 5'-D(*DGP*GP*TP*GP*AP*AP*AP*(TTD)P*AP*GP*CP*AP*GP*DGP)-3', DNA DAMAGE-BINDING PROTEIN 1, ... | 著者 | Scrima, A, Fischer, E.S, Iwai, S, Gut, H, Thoma, N.H. | 登録日 | 2011-09-08 | 公開日 | 2011-11-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation Cell(Cambridge,Mass.), 147, 2011
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3UK6
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![BU of 3uk6 by Molmil](/molmil-images/mine/3uk6) | Crystal Structure of the Tip48 (Tip49b) hexamer | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 2 | 著者 | Petukhov, M, Dagkessamanskaja, A, Bommer, M, Barrett, T, Tsaneva, I, Yakimov, A, Queval, R, Shvetsov, A, Khodorkovskiy, M, Kas, E, Grigoriev, M. | 登録日 | 2011-11-09 | 公開日 | 2012-07-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Large-Scale Conformational Flexibility Determines the Properties of AAA+ TIP49 ATPases. Structure, 20, 2012
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2EQM
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![BU of 2eqm by Molmil](/molmil-images/mine/2eqm) | Solution structure of the TUDOR domain of PHD finger protein 20-like 1 [Homo sapiens] | 分子名称: | PHD finger protein 20-like 1 | 著者 | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-30 | 公開日 | 2007-10-02 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the TUDOR domain of PHD finger protein 20-like 1 [Homo sapiens] To be Published
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3UO7
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![BU of 3uo7 by Molmil](/molmil-images/mine/3uo7) | |
3UVO
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![BU of 3uvo by Molmil](/molmil-images/mine/3uvo) | Crystal structure of WDR5 in complex with the WDR5-interacting motif of SET1B | 分子名称: | Histone-lysine N-methyltransferase SETD1B, WD repeat-containing protein 5 | 著者 | Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F. | 登録日 | 2011-11-30 | 公開日 | 2011-12-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases. Nucleic Acids Res., 40, 2012
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3UVY
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![BU of 3uvy by Molmil](/molmil-images/mine/3uvy) | Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K16acK20ac) | 分子名称: | Bromodomain-containing protein 4, Histone H4 | 著者 | Filippakopoulos, P, Felletar, I, Picaud, S, Keates, T, Muniz, J, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2011-11-30 | 公開日 | 2012-01-18 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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2B5M
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![BU of 2b5m by Molmil](/molmil-images/mine/2b5m) | Crystal Structure of DDB1 | 分子名称: | damage-specific DNA binding protein 1 | 著者 | Li, T, Chen, X, Garbutt, K.C, Zhou, P, Zheng, N. | 登録日 | 2005-09-28 | 公開日 | 2006-02-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase. Cell(Cambridge,Mass.), 124, 2006
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3ULE
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3UNZ
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![BU of 3unz by Molmil](/molmil-images/mine/3unz) | Aurora A in Complex with RPM1679 | 分子名称: | 1,2-ETHANEDIOL, 4-({4-[(2-fluorophenyl)amino]pyrimidin-2-yl}amino)benzoic acid, Aurora kinase A | 著者 | Martin, M.P, Zhu, J.-Y, Schonbrunn, E. | 登録日 | 2011-11-16 | 公開日 | 2012-01-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A. Acs Chem.Biol., 7, 2012
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3UOB
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3UOL
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![BU of 3uol by Molmil](/molmil-images/mine/3uol) | Aurora A in complex with SO2-162 | 分子名称: | 1,2-ETHANEDIOL, Aurora kinase A, N~4~-(2-chlorophenyl)-N~2~-[4-(1H-tetrazol-5-yl)phenyl]pyrimidine-2,4-diamine | 著者 | Martin, M.P, Zhu, J.-Y, Schonbrunn, E. | 登録日 | 2011-11-16 | 公開日 | 2012-01-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A. Acs Chem.Biol., 7, 2012
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3UOH
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![BU of 3uoh by Molmil](/molmil-images/mine/3uoh) | Aurora A in complex with RPM1722 | 分子名称: | 1,2-ETHANEDIOL, 4-({4-[(2-bromophenyl)amino]pyrimidin-2-yl}amino)benzoic acid, Aurora kinase A | 著者 | Martin, M.P, Zhu, J.-Y, Schonbrunn, E. | 登録日 | 2011-11-16 | 公開日 | 2012-01-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.8002 Å) | 主引用文献 | A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A. Acs Chem.Biol., 7, 2012
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3UOK
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![BU of 3uok by Molmil](/molmil-images/mine/3uok) | Aurora A in complex with YL5-81-1 | 分子名称: | 4-({4-[(2-chlorophenyl)amino]-5-fluoropyrimidin-2-yl}amino)benzoic acid, Aurora kinase A | 著者 | Martin, M.P, Zhu, J.-Y, Schonbrunn, E. | 登録日 | 2011-11-16 | 公開日 | 2012-01-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.9506 Å) | 主引用文献 | A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A. Acs Chem.Biol., 7, 2012
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