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8WAX
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BU of 8wax by Molmil
De novo transcribing complex 14 (TC14), the early elongation complex with Pol II positioned 14nt downstream of TSS
分子名称: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
著者Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
登録日2023-09-08
公開日2023-12-06
最終更新日2024-01-03
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAY
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BU of 8way by Molmil
De novo transcribing complex 15 (TC15), the early elongation complex with Pol II positioned 15nt downstream of TSS
分子名称: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
著者Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
登録日2023-09-08
公開日2023-12-06
最終更新日2024-01-03
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAW
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BU of 8waw by Molmil
De novo transcribing complex 13 (TC13), the early elongation complex with Pol II positioned 13nt downstream of TSS
分子名称: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
著者Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
登録日2023-09-08
公開日2023-12-06
最終更新日2024-01-03
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAT
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BU of 8wat by Molmil
De novo transcribing complex 10 (TC10), the early elongation complex with Pol II positioned 10nt downstream of TSS
分子名称: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
著者Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
登録日2023-09-08
公開日2023-12-06
最終更新日2024-01-03
実験手法ELECTRON MICROSCOPY (2.82 Å)
主引用文献Structural visualization of transcription initiation in action.
Science, 382, 2023
8WB0
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BU of 8wb0 by Molmil
De novo transcribing complex 17 (TC17), the early elongation complex with Pol II positioned 17nt downstream of TSS
分子名称: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
著者Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
登録日2023-09-08
公開日2023-12-06
最終更新日2024-01-03
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAU
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BU of 8wau by Molmil
De novo transcribing complex 11 (TC11), the early elongation complex with Pol II positioned 11nt downstream of TSS
分子名称: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
著者Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
登録日2023-09-08
公開日2023-12-06
最終更新日2024-01-03
実験手法ELECTRON MICROSCOPY (2.78 Å)
主引用文献Structural visualization of transcription initiation in action.
Science, 382, 2023
5E17
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BU of 5e17 by Molmil
T. thermophilus transcription initiation complex having a RRR discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 7 (RPo-GGG-7)
分子名称: DNA (27-MER), DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Zhang, Y, Ebright, R.H.
登録日2015-09-29
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection.
Science, 351, 2016
5E18
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BU of 5e18 by Molmil
T. thermophilus transcription initiation complex having a YYY discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 8 (RPo-CCC-8)
分子名称: DNA (28-MER), DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Zhang, Y, Ebright, R.H.
登録日2015-09-29
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection.
Science, 351, 2016
5WE4
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BU of 5we4 by Molmil
70S ribosome-EF-Tu wt complex with GppNHp
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Brown, Z, Frank, J.
登録日2017-07-07
公開日2018-04-25
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WDT
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BU of 5wdt by Molmil
70S ribosome-EF-Tu H84A complex with GppNHp
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Brown, Z, Frank, J.
登録日2017-07-06
公開日2018-04-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
6M99
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BU of 6m99 by Molmil
In situ structure of transcriptional enzyme complex and asymmetric inner capsid protein of aquareovirus at primed state
分子名称: PHOSPHATE ION, Putative core protein NTPase/VP5, VP2, ...
著者Ding, K, Zhou, Z.H.
登録日2018-08-23
公開日2018-09-05
最終更新日2019-11-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献In SituStructures of the Polymerase Complex and RNA Genome Show How Aquareovirus Transcription Machineries Respond to Uncoating.
J. Virol., 92, 2018
2PQF
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BU of 2pqf by Molmil
Human Poly(ADP-Ribose) Polymerase 12, Catalytic fragment in complex with an inhibitor 3-Aminobenzoic acid
分子名称: 3-AMINOBENZOIC ACID, CITRIC ACID, Poly [ADP-ribose] polymerase 12
著者Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hogbom, M, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日2007-05-02
公開日2007-05-15
最終更新日2015-04-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for Lack of ADP-ribosyltransferase Activity in Poly(ADP-ribose) Polymerase-13/Zinc Finger Antiviral Protein.
J.Biol.Chem., 290, 2015
1UK0
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BU of 1uk0 by Molmil
Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase with a novel inhibitor
分子名称: 2-{3-[4-(4-FLUOROPHENYL)-3,6-DIHYDRO-1(2H)-PYRIDINYL]PROPYL}-8-METHYL-4(3H)-QUINAZOLINONE, Poly [ADP-ribose] polymerase-1
著者Kinoshita, T.
登録日2003-08-13
公開日2004-01-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Inhibitor-induced structural change of the active site of human poly(ADP-ribose) polymerase.
Febs Lett., 556, 2004
1UK1
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BU of 1uk1 by Molmil
Crystal structure of human poly(ADP-ribose) polymerase complexed with a potent inhibitor
分子名称: 5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE, Poly [ADP-ribose] polymerase-1
著者Kinoshita, T.
登録日2003-08-14
公開日2004-09-14
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymerase
J.Med.Chem., 47, 2004
7NWI
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BU of 7nwi by Molmil
Mammalian pre-termination 80S ribosome with Empty-A site bound by Blasticidin S
分子名称: 18S ribosomal RNA, 28S ribosomal RNA+BlaS, 40S ribosomal protein S11, ...
著者Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C.
登録日2021-03-16
公開日2021-07-07
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA.
Nucleic Acids Res., 49, 2021
8HK1
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BU of 8hk1 by Molmil
The cryo-EM structure of human pre-17S U2 snRNP
分子名称: ATP-dependent RNA helicase DDX42, HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, ...
著者Zhang, X, Zhan, X, Shi, Y.
登録日2022-11-24
公開日2023-03-08
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly.
Nat Commun, 14, 2023
4WC3
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BU of 4wc3 by Molmil
Structure of tRNA-processing enzyme complex 1
分子名称: Poly A polymerase, RNA 76-mer
著者Yamashita, S, Tomita, K.
登録日2014-09-04
公開日2015-04-15
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme.
Structure, 23, 2015
4WC7
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BU of 4wc7 by Molmil
Structure of tRNA-processing enzyme complex 5
分子名称: CYTIDINE-5'-TRIPHOSPHATE, Poly A polymerase, RNA (75-MER)
著者Yamashita, S, Tomita, K.
登録日2014-09-04
公開日2015-04-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.102 Å)
主引用文献Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme.
Structure, 23, 2015
7EGC
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BU of 7egc by Molmil
p53-bound TFIID-based holo PIC on HDM2 promoter
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y.
登録日2021-03-24
公開日2021-05-12
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
6WMP
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BU of 6wmp by Molmil
F. tularensis RNAPs70-iglA DNA complex
分子名称: DNA NT-strand, DNA T-strand, DNA-directed RNA polymerase subunit alpha 1, ...
著者Travis, B.A, Brennan, R.G, Schumacher, M.A.
登録日2020-04-21
公開日2020-11-11
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Structural Basis for Virulence Activation of Francisella tularensis.
Mol.Cell, 81, 2021
6WMT
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BU of 6wmt by Molmil
F. tularensis RNAPs70-(MglA-SspA)-ppGpp-PigR-iglA DNA complex
分子名称: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ...
著者Travis, B.A, Brennan, R.G, Schumacher, M.A.
登録日2020-04-21
公開日2020-11-11
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.43 Å)
主引用文献Structural Basis for Virulence Activation of Francisella tularensis.
Mol.Cell, 81, 2021
6WMU
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BU of 6wmu by Molmil
E. coli RNAPs70-SspA-gadA DNA complex
分子名称: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ...
著者Travis, B.A, Brennan, R.G, Schumacher, M.A.
登録日2020-04-21
公開日2020-11-11
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Structural Basis for Virulence Activation of Francisella tularensis.
Mol.Cell, 81, 2021
6WMR
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BU of 6wmr by Molmil
F. tularensis RNAPs70-(MglA-SspA)-iglA DNA complex
分子名称: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ...
著者Travis, B.A, Brennan, R.G, Schumacher, M.A.
登録日2020-04-21
公開日2020-11-11
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Structural Basis for Virulence Activation of Francisella tularensis.
Mol.Cell, 81, 2021
4WC2
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BU of 4wc2 by Molmil
Crystal structure of tRNA nucleotidyltransferase complexed with a primer tRNA and an incoming ATP analog
分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, Poly A polymerase, ...
著者Yamashita, S, Tomita, K.
登録日2014-09-04
公開日2015-04-15
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme.
Structure, 23, 2015
4X0A
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BU of 4x0a by Molmil
Structure of tRNA-processing enzyme complex 6
分子名称: Poly A polymerase, RNA (73-MER)
著者Yamashita, S, Tomita, K.
登録日2014-11-21
公開日2015-04-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.505 Å)
主引用文献Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme.
Structure, 23, 2015

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件を2024-08-28に公開中

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