PDB: 30867 件ウェブページステータス検索Chemie searchBIRD

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7EIP	Crystal structure of ligand-free chondroitin ABC lyase I 分子名称: ACETATE ION, Chondroitin sulfate ABC endolyase, MAGNESIUM ION 著者 Takashima, M, Miyanaga, A, Eguchi, T. 登録日 2021-03-31 公開日 2021-08-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Substrate specificity of Chondroitinase ABC I based on analyses of biochemical reactions and crystal structures in complex with disaccharides. Glycobiology, 31, 2021
7EIS	Crystal structure of chondroitin ABC lyase I in complex with chondroitin disaccharide 0S 分子名称: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, Chondroitin sulfate ABC endolyase, MAGNESIUM ION 著者 Takashima, M, Miyanaga, A, Eguchi, T. 登録日 2021-03-31 公開日 2021-08-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Substrate specificity of Chondroitinase ABC I based on analyses of biochemical reactions and crystal structures in complex with disaccharides. Glycobiology, 31, 2021
7EIR	Crystal structure of chondroitin ABC lyase I in complex with chondroitin disaccharide 6S 分子名称: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-6-O-sulfo-beta-D-galactopyranose, Chondroitin sulfate ABC endolyase, GLYCEROL, ... 著者 Takashima, M, Miyanaga, A, Eguchi, T. 登録日 2021-03-31 公開日 2021-08-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Substrate specificity of Chondroitinase ABC I based on analyses of biochemical reactions and crystal structures in complex with disaccharides. Glycobiology, 31, 2021
7EIQ	Crystal structure of chondroitin ABC lyase I in complex with chondroitin disaccharide 4S 分子名称: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, Chondroitin sulfate ABC endolyase, MAGNESIUM ION 著者 Takashima, M, Miyanaga, A, Eguchi, T. 登録日 2021-03-31 公開日 2021-08-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Substrate specificity of Chondroitinase ABC I based on analyses of biochemical reactions and crystal structures in complex with disaccharides. Glycobiology, 31, 2021
7E0A	X-ray structure of human PPARgamma ligand binding domain-saroglitazar co-crystals obtained by co-crystallization 分子名称: (2S)-2-ethoxy-3-[4-[2-[2-methyl-5-(4-methylsulfanylphenyl)pyrrol-1-yl]ethoxy]phenyl]propanoic acid, Isoform 2 of Peroxisome proliferator-activated receptor gamma 著者 Kamata, S, Honda, A, Uchii, K, Machida, Y, Oyama, T, Ishii, I. 登録日 2021-01-27 公開日 2021-09-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.771 Å) 主引用文献 Structural Basis for Anti-non-alcoholic Fatty Liver Disease and Diabetic Dyslipidemia Drug Saroglitazar as a PPAR alpha / gamma Dual Agonist. Biol.Pharm.Bull., 44, 2021
7E5O	Crystal structure of SARS-CoV-2 RBD in complex with antibody NT-193 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NT-193 Heavy chain, NT-193 Light chain, ... 著者 Kita, S, Onodera, T, Adachi, Y, Moriayma, S, Nomura, T, Tadokoro, T, Anraku, Y, Yumoto, K, Tian, C, Fukuhara, H, Suzuki, T, Tonouchi, K, Sasaki, J, Sun, L, Hashiguchi, T, Takahashi, Y, Maenaka, K. 登録日 2021-02-19 公開日 2021-09-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A SARS-CoV-2 antibody broadly neutralizes SARS-related coronaviruses and variants by coordinated recognition of a virus-vulnerable site. Immunity, 54, 2021
7E4W	Human Transcriptional Co-activator PC4 (C-terminal Domain) in space group P1211 分子名称: Activated RNA polymerase II transcriptional coactivator p15 著者 Dev, A, Pandey, B, Basu, G. 登録日 2021-02-15 公開日 2021-09-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Insights on the disruption of the complex between human positive coactivator 4 and p53 by small molecules. Biochem.Biophys.Res.Commun., 578, 2021
7EBX	Crystal structure of juvenile hormone acid methyltransferase JHAMT in complex with S-adenosyl-L-homocysteine. 分子名称: S-ADENOSYL-L-HOMOCYSTEINE, juvenile hormone acid methyltransferase 著者 Guo, P.C, Zhang, Y.S, Zhang, L, Xu, H.Y, Xia, Q.Y. 登録日 2021-03-11 公開日 2021-09-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Structural basis for juvenile hormone biosynthesis by the juvenile hormone acid methyltransferase. J.Biol.Chem., 297, 2021
7E6R	Crystal structure of HCoV-NL63 3C-like protease,pH5.6 分子名称: 3C-like proteinase 著者 Gao, H.X, Zhang, Y.T, Zhong, F.L, Zhou, X.L, Li, J, Zhang, J. 登録日 2021-02-23 公開日 2021-10-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of human coronavirus NL63 main protease at different pH values Acta Crystallogr.,Sect.F, 77, 2021
7E6L	Crystal structure of HCoV-NL63 3C-like protease,pH5.0 分子名称: 3C-like proteinase 著者 Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J. 登録日 2021-02-22 公開日 2021-10-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.78037143 Å) 主引用文献 Crystal structures of human coronavirus NL63 main protease at different pH values Acta Crystallogr.,Sect.F, 77, 2021
7E5F	HUMAN PPAR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH TIPP703 OBTAINED BY SOAKING 分子名称: (2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}benzyl)butanoic acid, Peroxisome proliferator-activated receptor alpha 著者 Oyama, T, Kamata, S, Ishii, I, Miyachi, H. 登録日 2021-02-18 公開日 2021-10-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Crystal Structures of the Human Peroxisome Proliferator-Activated Receptor (PPAR) alpha Ligand-Binding Domain in Complexes with a Series of Phenylpropanoic Acid Derivatives Generated by a Ligand-Exchange Soaking Method. Biol.Pharm.Bull., 44, 2021
7EC0	Crystal structure of juvenile hormone acid methyltransferase JHAMT in complex with S-Adenosyl homocysteine and methyl farnesoate 分子名称: Juvenile hormone acid methyltransferase, Methyl farnesoate, S-ADENOSYL-L-HOMOCYSTEINE 著者 Guo, P.C, Zhang, Y.S, Zhang, L, Xu, H.Y, Xia, Q.Y. 登録日 2021-03-11 公開日 2021-09-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.494 Å) 主引用文献 Structural basis for juvenile hormone biosynthesis by the juvenile hormone acid methyltransferase. J.Biol.Chem., 297, 2021
7E6M	Crystal structure of Human coronavirus NL63 3C-like protease 分子名称: 3C-like proteinase 著者 Gao, H.X, Zhang, Y.T, Zhong, F.L, Zhou, X.L, Li, J, Zhang, J. 登録日 2021-02-22 公開日 2021-10-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.83445024 Å) 主引用文献 Crystal structures of human coronavirus NL63 main protease at different pH values Acta Crystallogr.,Sect.F, 77, 2021
7E5G	HUMAN PPAR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH YN4pai OBTAINED BY SOAKING 分子名称: (2S)-2-[[4-butoxy-3-[(pyren-1-ylcarbonylamino)methyl]phenyl]methyl]butanoic acid, Peroxisome proliferator-activated receptor alpha 著者 Oyama, T, Kamata, S, Ishii, I, Miyachi, H. 登録日 2021-02-18 公開日 2021-10-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Crystal Structures of the Human Peroxisome Proliferator-Activated Receptor (PPAR) alpha Ligand-Binding Domain in Complexes with a Series of Phenylpropanoic Acid Derivatives Generated by a Ligand-Exchange Soaking Method. Biol.Pharm.Bull., 44, 2021
7E24	Crystal structure of SDR family NAD(P)-dependent oxidoreductase from Exiguobacterium 分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase 著者 Chen, L, Tang, J, Yuan, S. 登録日 2021-02-04 公開日 2021-09-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7203 Å) 主引用文献 Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters Catalysis Science And Technology, 2021
7E5I	HUMAN PPAR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH APHM6 OBTAINED BY SOAKING 分子名称: (2S)-2-[[3-[[3-fluoranyl-4-(4-fluoranylphenoxy)phenyl]methylcarbamoyl]-4-methoxy-phenyl]methyl]butanoic acid, Peroxisome proliferator-activated receptor alpha 著者 Oyama, T, Kamata, S, Ishii, I, Miyachi, H. 登録日 2021-02-18 公開日 2021-10-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Crystal Structures of the Human Peroxisome Proliferator-Activated Receptor (PPAR) alpha Ligand-Binding Domain in Complexes with a Series of Phenylpropanoic Acid Derivatives Generated by a Ligand-Exchange Soaking Method. Biol.Pharm.Bull., 44, 2021
7E15	Protein ternary complex working for DNA replication initiation 分子名称: DNA polymerase II small subunit, Gins51, SsDNA-specific exonuclease 著者 Oyama, T, Ishino, Y. 登録日 2021-01-30 公開日 2021-10-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Family D DNA polymerase interacts with GINS to promote CMG-helicase in the archaeal replisome. Nucleic Acids Res., 50, 2022
7E6N	Crystal structure of HCoV-NL63 3C-like protease,pH5.2 分子名称: 3C-like proteinase 著者 Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J. 登録日 2021-02-22 公開日 2021-10-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8413 Å) 主引用文献 Crystal structures of human coronavirus NL63 main protease at different pH values Acta Crystallogr.,Sect.F, 77, 2021
7E5H	HUMAN PPAR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH APHM6 OBTAINED BY COCRYSTALLIZATION 分子名称: (2S)-2-[[3-[[3-fluoranyl-4-(4-fluoranylphenoxy)phenyl]methylcarbamoyl]-4-methoxy-phenyl]methyl]butanoic acid, Peroxisome proliferator-activated receptor alpha 著者 Oyama, T, Kamata, S, Ishii, I, Miyachi, H. 登録日 2021-02-18 公開日 2021-10-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Crystal Structures of the Human Peroxisome Proliferator-Activated Receptor (PPAR) alpha Ligand-Binding Domain in Complexes with a Series of Phenylpropanoic Acid Derivatives Generated by a Ligand-Exchange Soaking Method. Biol.Pharm.Bull., 44, 2021
7EO6	X-ray structure analysis of xylanase 分子名称: Endo-1,4-beta-xylanase, IODIDE ION 著者 Wan, Q, Yi, Y, Xu, S. 登録日 2021-04-21 公開日 2021-10-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Characterization and structural analysis of a thermophilic GH11 xylanase from compost metatranscriptome. Appl.Microbiol.Biotechnol., 105, 2021
7DXL	Fragment-based Lead Discovery of Indazole-based Compounds as AXL Kinase Inhibitors 分子名称: 3-[4-[6-chloranyl-5-[[(3R)-pyrrolidin-3-yl]amino]-1H-indazol-3-yl]pyrazol-1-yl]benzenecarbonitrile, Tyrosine-protein kinase Mer 著者 Anantharajan, J, Baburajendran, N. 登録日 2021-01-19 公開日 2021-10-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.146 Å) 主引用文献 Fragment-based lead discovery of indazole-based compounds as AXL kinase inhibitors. Bioorg.Med.Chem., 49, 2021
7EO7	Crystal structure of HCoV-NL63 3C-like protease in complex with an inhibitor Shikonin 分子名称: 2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione, 3C-like proteinase 著者 Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J. 登録日 2021-04-21 公開日 2021-10-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.24916625 Å) 主引用文献 Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus. J.Virol., 96, 2022
7ELG	LC3B modificated with a covalent probe 分子名称: 2-methylidene-5-thiophen-2-yl-cyclohexane-1,3-dione, Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION 著者 Fan, S, Wan, W. 登録日 2021-04-10 公開日 2021-10-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.599 Å) 主引用文献 Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein. Angew.Chem.Int.Ed.Engl., 60, 2021
7E2B	GDPD mutant complex from Pyrococcus furiosus DSM 3638 分子名称: CHOLINE ION, Glycerophosphodiester phosphodiesterase, MAGNESIUM ION, ... 著者 Wang, Y.H, Wang, J, Wang, F.H. 登録日 2021-02-05 公開日 2022-02-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Observation of the GPC production during hydrolysis of LPC by GDPD D60A from Pyrococcus furiosus DSM 3638 To Be Published
7EL2	Crystal structure of apo-HpaR from Acinetobacter baumannii 分子名称: Homoprotocatechuate degradation operon regulator HpaR 著者 Permsirivisarn, P, Pakotiprapha, D. 登録日 2021-04-07 公開日 2022-01-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Mechanism of transcription regulation by Acinetobacter baumannii HpaR in the catabolism of p-hydroxyphenylacetate. Febs J., 289, 2022

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