7E5O

Crystal structure of SARS-CoV-2 RBD in complex with antibody NT-193

Summary for 7E5O

Entry DOI	10.2210/pdb7e5o/pdb
Descriptor	NT-193 Heavy chain, NT-193 Light chain, Spike protein S1, ... (5 entities in total)
Functional Keywords	spike, igg, viral protein
Biological source	Homo sapiens More
Total number of polymer chains	3
Total formula weight	74064.90
Authors	Kita, S.,Onodera, T.,Adachi, Y.,Moriayma, S.,Nomura, T.,Tadokoro, T.,Anraku, Y.,Yumoto, K.,Tian, C.,Fukuhara, H.,Suzuki, T.,Tonouchi, K.,Sasaki, J.,Sun, L.,Hashiguchi, T.,Takahashi, Y.,Maenaka, K. (deposition date: 2021-02-19, release date: 2021-09-08, Last modification date: 2023-11-29)
Primary citation	Onodera, T.,Kita, S.,Adachi, Y.,Moriyama, S.,Sato, A.,Nomura, T.,Sakakibara, S.,Inoue, T.,Tadokoro, T.,Anraku, Y.,Yumoto, K.,Tian, C.,Fukuhara, H.,Sasaki, M.,Orba, Y.,Shiwa, N.,Iwata, N.,Nagata, N.,Suzuki, T.,Sasaki, J.,Sekizuka, T.,Tonouchi, K.,Sun, L.,Fukushi, S.,Satofuka, H.,Kazuki, Y.,Oshimura, M.,Kurosaki, T.,Kuroda, M.,Matsuura, Y.,Suzuki, T.,Sawa, H.,Hashiguchi, T.,Maenaka, K.,Takahashi, Y. A SARS-CoV-2 antibody broadly neutralizes SARS-related coronaviruses and variants by coordinated recognition of a virus-vulnerable site. Immunity, 54:2385-, 2021 Cited by PubMed: 34508662 DOI: 10.1016/j.immuni.2021.08.025 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation