PDB: 31489 件ウェブページステータス検索Chemie searchBIRD

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5MV4	ACC1 Fab fragment in complex with citrullinated CII616-639 epitope of collagen type II (ptm23) 分子名称: ACC1 antibody Fab fragment, heavy chain, light chain, ... 著者 Dobritzsch, D, Holmdahl, R, Ge, C. 登録日 2017-01-15 公開日 2017-07-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage. JCI Insight, 2, 2017
5M7F	Human porphobilinogen deaminase in complex with DPM cofactor 分子名称: 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase, SULFATE ION 著者 Pluta, P, Millet, O, Roversi, P, Rojas, A.L, Gu, S. 登録日 2016-10-27 公開日 2017-11-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Structural basis of pyrrole polymerization in human porphobilinogen deaminase. Biochim Biophys Acta Gen Subj, 1862, 2018
6R9D	Crystal structure of an asymmetric dimer of the N-terminal domain of Euprosthenops australis Major Ampullate Spidroin 1 (dragline silk) 分子名称: Major ampullate spidroin 1, SULFATE ION 著者 Knight, S.D, Jiang, W, Askarieh, G. 登録日 2019-04-03 公開日 2019-07-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the N-terminal domain of Euprosthenops australis dragline silk suggests that conversion of spidroin dope to spider silk involves a conserved asymmetric dimer intermediate. Acta Crystallogr D Struct Biol, 75, 2019
5M9V	Human angiogenin PD/ALS variant R121C 分子名称: Angiogenin, GLUTATHIONE, L(+)-TARTARIC ACID 著者 Bradshaw, W.J, Rehman, S, Pham, T.T.K, Thiyagarajan, N, Lee, R.L, Subramanian, V, Acharya, K.R. 登録日 2016-11-02 公開日 2017-02-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis. Sci Rep, 7, 2017
6RBP	Crystal structure of NAD kinase 1 from Listeria monocytogenes in complexe with an adenine derivative 分子名称: 9-(4-azidobutyl)purin-6-amine, CITRIC ACID, NAD kinase 1 著者 Gelin, M, Labesse, G. 登録日 2019-04-11 公開日 2020-02-19 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.473 Å) 主引用文献 From Substrate to Fragments to Inhibitor ActiveIn VivoagainstStaphylococcus aureus. Acs Infect Dis., 6, 2020
6RBY	Crystal structure of NAD kinase 1 from Listeria monocytogenes in complexe with an adenine derivative 分子名称: 4-(6-azanyl-8-bromanyl-purin-9-yl)butan-1-ol, CITRIC ACID, NAD kinase 1 著者 Gelin, M, Labesse, G. 登録日 2019-04-11 公開日 2020-02-19 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.312 Å) 主引用文献 From Substrate to Fragments to Inhibitor ActiveIn VivoagainstStaphylococcus aureus. Acs Infect Dis., 6, 2020
5MBT	CeuE (H227L, Y288F variant) a periplasmic protein from Campylobacter jejuni 分子名称: Enterochelin uptake periplasmic binding protein 著者 Wilde, E.J, Blagova, E.V, Hughes, A, Raines, D.J, Moroz, O.V, Turkenburg, J.P, Duhme-Klair, A.-K, Wilson, K.S. 登録日 2016-11-08 公開日 2017-04-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM(4-) siderophore analogues of varied linker length. Sci Rep, 7, 2017
6R9W	Crystal structure of InhA in complex with AP-124 inhibitor 分子名称: (2~{S})-1-(benzimidazol-1-yl)-3-(2,3-dihydro-1~{H}-inden-5-yloxy)propan-2-ol, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Takebayashi, Y, Hinchliffe, P, Spencer, J. 登録日 2019-04-04 公開日 2019-12-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Discovery of New and Potent InhA Inhibitors as Antituberculosis Agents: Structure-Based Virtual Screening Validated by Biological Assays and X-ray Crystallography. J.Chem.Inf.Model., 60, 2020
5MC9	Crystal structure of the heterotrimeric integrin-binding region of laminin-111 分子名称: CALCIUM ION, Laminin subunit alpha-1, Laminin subunit beta-1, ... 著者 Pulido, D, Hohenester, E. 登録日 2016-11-09 公開日 2017-02-08 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111. Structure, 25, 2017
5MCN	Radiation damage to GH7 Family Cellobiohydrolase from Daphnia pulex: Dose (DWD) 22.7 MGy 分子名称: Cellobiohydrolase CHBI, GLYCEROL, SULFATE ION 著者 Bury, C.S, McGeehan, J.E, Ebrahim, A, Garman, E.F. 登録日 2016-11-10 公開日 2017-01-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 OH cleavage from tyrosine: debunking a myth. J Synchrotron Radiat, 24, 2017
6RB0	STRUCTURE OF ESTER-HYDROLASE EH1AB1 FROM THE METAGENOME OF LAKE ARREO COMPLEXED WITH A DERIVATIVE OF METHYL 4-NITROPHENYL HEXYLPHOSPHONATE 分子名称: EH1AB1, GLYCEROL, methyl hydrogen (R)-hexylphosphonate 著者 Cea-Rama, I, Sanz-Aparicio, J. 登録日 2019-04-08 公開日 2019-12-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Genetically engineered proteins with two active sites for enhanced biocatalysis and synergistic chemo- and biocatalysis Nat Catal, 3, 2020
5MVM	X-ray structure of the F14'A -N15'A double mutant of GLIC in complex with propofol 分子名称: 2,6-BIS(1-METHYLETHYL)PHENOL, ACETATE ION, CHLORIDE ION, ... 著者 Fourati, Z, Delarue, M. 登録日 2017-01-16 公開日 2018-03-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 X-ray structure of the F14'A -N15'A double mutant of GLIC in complex with propofol To Be Published
6R36	T. brucei farnesyl pyrophosphate synthase (FPPS) 分子名称: DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, Farnesyl pyrophosphate synthase 著者 Muenzker, L, Petrick, J.K, Schleberger, C, Jahnke, W. 登録日 2019-03-19 公開日 2020-04-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Fragment-Based Discovery of Non-bisphosphonate Binders of Trypanosoma brucei Farnesyl Pyrophosphate Synthase. Chembiochem, 21, 2020
5MDQ	Crystal structure of outer membrane expressed Chitoporin VhChip from Vibrio harveyi 分子名称: Chitoporin, SODIUM ION 著者 Zahn, M, van den Berg, B. 登録日 2016-11-13 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for chitin acquisition by marine Vibrio species. Nat Commun, 9, 2018
5MWP	The structure of MR in complex with AZD9977. 分子名称: 2-[(3~{S})-7-fluoranyl-4-[(3-oxidanylidene-4~{H}-1,4-benzoxazin-6-yl)carbonyl]-2,3-dihydro-1,4-benzoxazin-3-yl]-~{N}-methyl-ethanamide, Mineralocorticoid receptor, NCOA1 peptide 著者 Edman, K, Aagaard, A, Backstrom, S. 登録日 2017-01-19 公開日 2018-03-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion. PLoS ONE, 13, 2018
5ME9	Crystal structure of yeast Cdt1 (N terminal and middle domain), form 1. 分子名称: Cell division cycle protein CDT1, GLYCEROL, SULFATE ION 著者 Pye, V.E, Frigola, J, Diffley, J.F.X, Cherepanov, P. 登録日 2016-11-14 公開日 2017-05-17 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Cdt1 stabilizes an open MCM ring for helicase loading. Nat Commun, 8, 2017
5MWY	The structure of MR in complex with eplerenone. 分子名称: Mineralocorticoid receptor, NCOA1, eplerenone 著者 Edman, K, Aagaard, A, Backstrom, S. 登録日 2017-01-20 公開日 2018-03-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion. PLoS ONE, 13, 2018
6R5O	The crystal structure the Glycoside Hydrolase BglX inactive mutant D286N from P. aeruginosa in complex with two glucose molecules 分子名称: MAGNESIUM ION, Periplasmic beta-glucosidase, beta-D-glucopyranose 著者 Batuecas, M.T, Hermoso, J.A. 登録日 2019-03-25 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Catalytic Cycle of Glycoside Hydrolase BglX fromPseudomonas aeruginosaand Its Implications for Biofilm Formation. Acs Chem.Biol., 15, 2020
6R62	Crystal structure of a class II pyruvate aldolase from Sphingomonas wittichii RW1 in complex with hydroxypyruvate 分子名称: 3-HYDROXYPYRUVIC ACID, ACETATE ION, BROMIDE ION, ... 著者 Marsden, S.R, Mestrom, L, Hagedoorn, P.L, Bento, I, McMillan, D.G.G, Hanefeld, U. 登録日 2019-03-26 公開日 2019-05-29 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 CH-Pi Interactions Promote the Conversion of Hydroxypyruvate in a Class II Pyruvate Aldolase Adv.Synth.Catal., 2019
5MDN	Structure of the family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis 分子名称: DNA polymerase, MAGNESIUM ION 著者 Guo, J, Zhang, W, Coker, A.R, Wood, S.P, Cooper, J.B, Rashid, N, Akhtar, M. 登録日 2016-11-12 公開日 2016-12-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of the family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis. Acta Crystallogr D Struct Biol, 73, 2017
5NN6	Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with N-hydroxyethyl-1-deoxynojirimycin 分子名称: (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Roig-Zamboni, V, Cobucci-Ponzano, B, Iacono, R, Ferrara, M.C, Germany, S, Parenti, G, Bourne, Y, Moracci, M. 登録日 2017-04-08 公開日 2017-10-25 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of human lysosomal acid alpha-glucosidase-a guide for the treatment of Pompe disease. Nat Commun, 8, 2017
5NNJ	Dimer structure of Sortilin ectodomain crystal form 3, 4.0 Angstrom 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Sortilin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Leloup, N.O.L, Janssen, B.J.C. 登録日 2017-04-09 公開日 2017-11-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release. Nat Commun, 8, 2017
5N1U	Structure of xEco2 acetyltransferase domain 分子名称: COENZYME A, XEco2 著者 Chao, W.C.H, Wade, B.O, Singleton, M.R. 登録日 2017-02-06 公開日 2017-03-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.976 Å) 主引用文献 Structural Basis of Eco1-Mediated Cohesin Acetylation. Sci Rep, 7, 2017
6R4B	Aurora-A in complex with shape-diverse fragment 56 分子名称: (6~{S})-6-[2,4-bis(fluoranyl)phenyl]-~{N},~{N},4-trimethyl-2-oxidanylidene-5,6-dihydro-1~{H}-pyrimidine-5-carboxamide, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ... 著者 Bayliss, R, McIntyre, P.J. 登録日 2019-03-22 公開日 2019-05-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Construction of a Shape-Diverse Fragment Set: Design, Synthesis and Screen against Aurora-A Kinase. Chemistry, 25, 2019
5N2H	Structure of the E9 DNA polymerase exonuclease deficient mutant (D166A+E168A) from vaccinia virus 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Tarbouriech, N, Burmeister, W.P, Iseni, F. 登録日 2017-02-07 公開日 2017-11-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding. Nat Commun, 8, 2017

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