5N2H

Structure of the E9 DNA polymerase exonuclease deficient mutant (D166A+E168A) from vaccinia virus

Summary for 5N2H

Entry DOI	10.2210/pdb5n2h/pdb
Descriptor	DNA polymerase, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... (6 entities in total)
Functional Keywords	vaccinia virus, dna polymerase, protein-protein interface, family b polymerase, processivity factor, transferase
Biological source	Vaccinia virus Copenhagen
Total number of polymer chains	1
Total formula weight	118376.67
Authors	Tarbouriech, N.,Burmeister, W.P.,Iseni, F. (deposition date: 2017-02-07, release date: 2017-11-29, Last modification date: 2024-01-17)
Primary citation	Tarbouriech, N.,Ducournau, C.,Hutin, S.,Mas, P.J.,Man, P.,Forest, E.,Hart, D.J.,Peyrefitte, C.N.,Burmeister, W.P.,Iseni, F. The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding. Nat Commun, 8:1455-1455, 2017 Cited by PubMed: 29129932 DOI: 10.1038/s41467-017-01542-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.81 Å)

Structure validation