4KJI
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8EZ6
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4KRF
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4K32
| Crystal structure of geneticin bound to the leishmanial rRNA A-site | 分子名称: | GENETICIN, RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*GP*UP*UP*CP*CP*GP*GP*AP*AP*AP*AP*GP*UP*CP*GP*C)-3') | 著者 | Shalev, M, Kondo, J, Adir, N, Baasov, T. | 登録日 | 2013-04-10 | 公開日 | 2013-07-31 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Identification of the molecular attributes required for aminoglycoside activity against Leishmania. Proc.Natl.Acad.Sci.USA, 110, 2013
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1SOO
| ADENYLOSUCCINATE SYNTHETASE INHIBITED BY HYDANTOCIDIN 5'-MONOPHOSPHATE | 分子名称: | ADENYLOSUCCINATE SYNTHETASE, BETA-MERCAPTOETHANOL, HYDANTOCIDIN-5'-PHOSPHATE, ... | 著者 | Cowan-Jacob, S.W. | 登録日 | 1996-05-07 | 公開日 | 1997-09-04 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The mode of action and the structure of a herbicide in complex with its target: binding of activated hydantocidin to the feedback regulation site of adenylosuccinate synthetase. Proc.Natl.Acad.Sci.USA, 93, 1996
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1YLF
| X-ray crystal structure of BC1842 protein from Bacillus cereus, a member of the Rrf2 family of putative transcription regulators. | 分子名称: | CHLORIDE ION, RRF2 family protein | 著者 | Osipiuk, J, Wu, R, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2005-01-19 | 公開日 | 2005-02-01 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | X-ray crystal structure of BC1842 protein from Bacillus cereus, a member of the Rrf2 family of putative transcription regulators. To be Published
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4Q0N
| Crystal Structure of the fifth bromodomain of Human Poly-bromodomain containing protein 1 (PB1) in complex with a hydroxyphenyl-propenone ligand | 分子名称: | (2E)-1-(2-hydroxyphenyl)-3-(2,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridin-6-yl)prop-2-en-1-one, 1,2-ETHANEDIOL, Protein polybromo-1 | 著者 | Filippakopoulos, P, Picaud, S, Felletar, I, Martin, S, Monteiro, O, Fedorov, O, Chaikuad, A, Yue, W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2014-04-02 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Crystal Structure of the fifth bromodomain of Human Poly-bromodomain containing protein 1 (PB1) in complex with a hydroxyphenyl-propenone ligand To be Published
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4K7O
| HUMAN PEROXIREDOXIN 5 with a fragment | 分子名称: | 4-tert-butylbenzene-1,2-diol, DIMETHYL SULFOXIDE, Peroxiredoxin-5, ... | 著者 | Guichou, J.F. | 登録日 | 2013-04-17 | 公開日 | 2014-04-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Comparing Binding Modes of Analogous Fragments Using NMR in Fragment-Based Drug Design: Application to PRDX5 Plos One, 9, 2014
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5I2Y
| Crystal Structure of TPP1 K170A | 分子名称: | Adrenocortical dysplasia protein homolog | 著者 | Nandakumar, J, Smith, E.M. | 登録日 | 2016-02-09 | 公開日 | 2016-11-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural and functional consequences of a disease mutation in the telomere protein TPP1. Proc.Natl.Acad.Sci.USA, 113, 2016
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4K95
| Crystal Structure of Parkin | 分子名称: | E3 ubiquitin-protein ligase parkin, ZINC ION | 著者 | Seirafi, M, Menade, M, Sauve, V, Kozlov, G, Trempe, J.-F, Nagar, B, Gehring, K. | 登録日 | 2013-04-19 | 公開日 | 2013-05-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (6.499 Å) | 主引用文献 | Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science, 340, 2013
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1SM8
| M. tuberculosis dUTPase complexed with chromium and dUTP | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHROMIUM ION, DEOXYURIDINE-5'-TRIPHOSPHATE, ... | 著者 | Sawaya, M.R, Chan, S, Segelke, B, Lekin, T, Krupka, H, Cho, U.S, Kim, M.-Y, So, M, Kim, C.-Y, Naranjo, C.M, Rogers, Y.C, Park, M.S, Waldo, G.S, Pashkov, I, Cascio, D, Yeates, T.O, Perry, J.L, Terwilliger, T.C, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2004-03-08 | 公開日 | 2004-03-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism. J.Mol.Biol., 341, 2004
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3MC8
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5I2X
| Crystal Structure of TPP1 K170del | 分子名称: | Adrenocortical dysplasia protein homolog | 著者 | Nandakumar, J, Smith, E. | 登録日 | 2016-02-09 | 公開日 | 2016-11-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural and functional consequences of a disease mutation in the telomere protein TPP1. Proc.Natl.Acad.Sci.USA, 113, 2016
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4KCB
| Crystal Structure of Exo-1,5-alpha-L-arabinanase from Bovine Ruminal Metagenomic Library | 分子名称: | Arabinan endo-1,5-alpha-L-arabinosidase, PHOSPHATE ION | 著者 | Santos, C.R, Polo, C.C, Costa, M.C.M.F, Nascimento, A.F.Z, Wong, D.W.S, Murakami, M.T. | 登録日 | 2013-04-24 | 公開日 | 2014-02-05 | 最終更新日 | 2014-04-09 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Mechanistic strategies for catalysis adopted by evolutionary distinct family 43 arabinanases. J.Biol.Chem., 289, 2014
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2BX2
| Catalytic domain of E. coli RNase E | 分子名称: | MAGNESIUM ION, RIBONUCLEASE E, RNA (5'-R(*UP*UP*UP*AP*CP*AP*GP*UP*AP*UP*UP* UP*GP*UP*U)-3'), ... | 著者 | Marcaida, M.J, Callaghan, A.J, Scott, W.G, Luisi, B.F. | 登録日 | 2005-07-21 | 公開日 | 2005-10-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structure of E. Coli Rnase E Catalytic Domain and Implications for RNA Processing and Turnover Nature, 437, 2005
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1S9S
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3AA9
| Crystal Structure Analysis of the Mutant CutA1 (E61V) from E. coli | 分子名称: | Divalent-cation tolerance protein cutA | 著者 | Matsuura, Y, Tanaka, T, Bagautdinov, B, Kunishima, N, Yutani, K. | 登録日 | 2009-11-12 | 公開日 | 2010-08-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Remarkable improvement in the heat stability of CutA1 from Escherichia coli by rational protein design J.Biochem., 148, 2010
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5BT1
| histone chaperone Hif1 playing with histone H2A-H2B dimer | 分子名称: | HAT1-interacting factor 1, Histone H2A.1, Histone H2B.1 | 著者 | Liu, H, Zhang, M, Gao, Y, Teng, M, Niu, L. | 登録日 | 2015-06-02 | 公開日 | 2016-10-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Structural Insights into the Association of Hif1 with Histones H2A-H2B Dimer and H3-H4 Tetramer Structure, 24, 2016
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3MH7
| HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues | 分子名称: | 5-mer peptide, Protease do | 著者 | Krojer, T, Sawa, J, Huber, R, Clausen, T. | 登録日 | 2010-04-07 | 公開日 | 2010-06-30 | 最終更新日 | 2014-03-05 | 実験手法 | X-RAY DIFFRACTION (2.961 Å) | 主引用文献 | HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues Nat.Struct.Mol.Biol., 17, 2010
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1SG9
| Crystal structure of Thermotoga maritima protein HEMK, an N5-glutamine methyltransferase | 分子名称: | GLUTAMINE, S-ADENOSYLMETHIONINE, hemK protein | 著者 | Agarwal, R, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2004-02-23 | 公開日 | 2004-08-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A novel mode of dimerization via formation of a glutamate anhydride crosslink in a protein crystal structure. Proteins, 71, 2008
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3MCR
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5IAB
| Caspase 3 V266D | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACE-ASP-GLU-VAL-ASK, Caspase-3 | 著者 | Maciag, J.J, Mackenzie, S.H, Tucker, M.B, Schipper, J.L, Swartz, P.D, Clark, A.C. | 登録日 | 2016-02-21 | 公開日 | 2016-10-26 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. Proc.Natl.Acad.Sci.USA, 113, 2016
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4KIU
| Design and structural analysis of aromatic inhibitors of type II dehydroquinate dehydratase from Mycobacterium tuberculosis - compound 49d [5-[(3-nitrobenzyl)oxy]benzene-1,3-dicarboxylic acid] | 分子名称: | 3-dehydroquinate dehydratase, 5-[(3-nitrobenzyl)oxy]benzene-1,3-dicarboxylic acid | 著者 | Dias, M.V.B, Howard, N.G, Blundell, T.L, Abell, C. | 登録日 | 2013-05-02 | 公開日 | 2014-05-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Design and Structural Analysis of Aromatic Inhibitors of Type II Dehydroquinase from Mycobacterium tuberculosis. Chemmedchem, 10, 2015
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4KRW
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2ZZN
| The complex structure of aTrm5 and tRNACys | 分子名称: | MAGNESIUM ION, RNA (71-MER), S-ADENOSYLMETHIONINE, ... | 著者 | Goto-Ito, S, Ito, T, Yokoyama, S. | 登録日 | 2009-02-19 | 公開日 | 2009-09-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation. Nat.Struct.Mol.Biol., 16, 2009
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