8VG2
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5G6V
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![BU of 5g6v by Molmil](/molmil-images/mine/5g6v) | Crystal structure of the PCTAIRE1 kinase in complex with inhibitor | 分子名称: | 1,2-ETHANEDIOL, 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide, CYCLIN-DEPENDENT KINASE 16 | 著者 | Dixon-Clarke, S.E, Galan Bartual, S, Elkins, J, Savitsky, P, Kopec, J, Mackenzie, A, Tallant, C, Heroven, C, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A. | 登録日 | 2016-08-16 | 公開日 | 2016-11-23 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16. Biochem.J., 474, 2017
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5D6E
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![BU of 5d6e by Molmil](/molmil-images/mine/5d6e) | Structure of human methionine aminopeptidase 2 with covalent spiroepoxytriazole inhibitor (-)-31b | 分子名称: | (4R,7S)-7-hydroxy-1-(4-methoxybenzyl)-7-methyl-4,5,6,7-tetrahydro-1H-benzotriazol-4-yl propan-2-ylcarbamate, COBALT (II) ION, Methionine aminopeptidase 2, ... | 著者 | Janowski, R, Miller, A.K, Niessing, D. | 登録日 | 2015-08-12 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Spiroepoxytriazoles Are Fumagillin-like Irreversible Inhibitors of MetAP2 with Potent Cellular Activity. Acs Chem.Biol., 11, 2016
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7LLE
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7LN0
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![BU of 7ln0 by Molmil](/molmil-images/mine/7ln0) | Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and Ub6 (Class 2) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Hexa-ubiquitin, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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8VG0
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3BQ5
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![BU of 3bq5 by Molmil](/molmil-images/mine/3bq5) | Crystal Structure of T. maritima Cobalamin-Independent Methionine Synthase complexed with Zn2+ and Homocysteine (Monoclinic) | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase, ... | 著者 | Pejchal, R, Smith, J.L, Ludwig, M.L. | 登録日 | 2007-12-19 | 公開日 | 2008-03-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Metal active site elasticity linked to activation of homocysteine in methionine synthases. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2WGF
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7LB6
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![BU of 7lb6 by Molmil](/molmil-images/mine/7lb6) | PDX1.2/PDX1.3 co-expression complex | 分子名称: | Pyridoxal 5'-phosphate synthase subunit PDX1.3, Pyridoxal 5'-phosphate synthase-like subunit PDX1.2 | 著者 | Novikova, I.V, Evans, J.E. | 登録日 | 2021-01-07 | 公開日 | 2021-09-22 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Tunable Heteroassembly of a Plant Pseudoenzyme-Enzyme Complex. Acs Chem.Biol., 16, 2021
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2BP7
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![BU of 2bp7 by Molmil](/molmil-images/mine/2bp7) | New crystal form of the Pseudomonas putida branched-chain dehydrogenase (E1) | 分子名称: | 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT | 著者 | Frank, R.A.W, Pratap, J.V, Pei, X.Y, Perham, R.N, Luisi, B.F. | 登録日 | 2005-04-18 | 公開日 | 2005-08-10 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The Molecular Origins of Specificity in the Assembly of a Multienzyme Complex. Structure, 13, 2005
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5D98
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![BU of 5d98 by Molmil](/molmil-images/mine/5d98) | Influenza C Virus RNA-dependent RNA Polymerase - Space group P43212 | 分子名称: | MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... | 著者 | Hengrung, N, El Omari, K, Serna Martin, I, Vreede, F.T, Cusack, S, Rambo, R.P, Vonrhein, C, Bricogne, G, Stuart, D.I, Grimes, J.M, Fodor, E. | 登録日 | 2015-08-18 | 公開日 | 2015-10-21 | 最終更新日 | 2017-09-13 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Crystal structure of the RNA-dependent RNA polymerase from influenza C virus. Nature, 527, 2015
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7LN6
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![BU of 7ln6 by Molmil](/molmil-images/mine/7ln6) | Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (CHAPSO, Class 2, Open State) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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1NXJ
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![BU of 1nxj by Molmil](/molmil-images/mine/1nxj) | Structure of Rv3853 from Mycobacterium tuberculosis | 分子名称: | GLYOXYLIC ACID, L(+)-TARTARIC ACID, Probable S-adenosylmethionine:2-demethylmenaquinone methyltransferase | 著者 | Johnston, J.M, Arcus, V.L, Baker, E.N, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2003-02-10 | 公開日 | 2003-07-29 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of a Putative Methyltransferase from Mycobacterium tuberculosis: Misannotation of a Genome Clarified by Protein Structural Analysis J.Bacteriol., 185, 2003
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8VDD
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![BU of 8vdd by Molmil](/molmil-images/mine/8vdd) | Crystal structure of Proinsulin C-peptide bound to HLA-DQ8 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, MHC class II HLA-DQ-alpha chain, ... | 著者 | Tran, T.M, Lim, J.J, Loh, T.Y, Mannering, I.S, Rossjohn, J, Reid, H.H. | 登録日 | 2023-12-14 | 公開日 | 2024-08-07 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A structural basis of T cell cross-reactivity to native and spliced self-antigens presented by HLA-DQ8. J.Biol.Chem., 2024
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2VUU
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![BU of 2vuu by Molmil](/molmil-images/mine/2vuu) | Crystal structure of NADP-bound NmrA-AreA zinc finger complex | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NITROGEN METABOLITE REPRESSION REGULATOR NMRA, NITROGEN REGULATORY PROTEIN AREA, ... | 著者 | Kotaka, M, Johnson, C, Lamb, H.K, Hawkins, A.R, Ren, J, Stammers, D.K. | 登録日 | 2008-05-30 | 公開日 | 2008-07-29 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Analysis of the Recognition of the Negative Regulator Nmra and DNA by the Zinc Finger from the Gata-Type Transcription Factor Area. J.Mol.Biol., 381, 2008
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4M6U
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7RK6
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![BU of 7rk6 by Molmil](/molmil-images/mine/7rk6) | Aplysia Slo1 with Barium | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, BARIUM ION, BK channel, ... | 著者 | Zhu, J, Srivastava, S, Cachau, R, Holmgren, M. | 登録日 | 2021-07-22 | 公開日 | 2022-06-22 | 最終更新日 | 2023-04-05 | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | 主引用文献 | CryoEM structure of Aplysia Slo1 with 0 mM Ba2+ at 2.91 A To Be Published
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5G5I
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![BU of 5g5i by Molmil](/molmil-images/mine/5g5i) | S. enterica HisA mutant D10G | 分子名称: | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, PHOSPHATE ION | 著者 | Guo, X, Soderholm, A, Newton, M, Nasvall, J, Andersson, D, Patrick, W, Selmer, M. | 登録日 | 2016-05-25 | 公開日 | 2017-04-19 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4IDJ
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![BU of 4idj by Molmil](/molmil-images/mine/4idj) | S.Aureus a-hemolysin monomer in complex with Fab | 分子名称: | Alpha-hemolysin, Fab Heavy chain, Fab Light chain, ... | 著者 | Strop, P. | 登録日 | 2012-12-12 | 公開日 | 2013-06-26 | 最終更新日 | 2021-05-26 | 実験手法 | X-RAY DIFFRACTION (3.36 Å) | 主引用文献 | Mechanism of Action and In Vivo Efficacy of a Human-Derived Antibody against Staphylococcus aureus alpha-Hemolysin. J.Mol.Biol., 425, 2013
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7LN5
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![BU of 7ln5 by Molmil](/molmil-images/mine/7ln5) | Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (CHAPSO, Class 1, Close State) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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5G69
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![BU of 5g69 by Molmil](/molmil-images/mine/5g69) | Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-(2-(3-Fluorobenzylamino)ethyl)quinolin-2-amine | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 7-{2-[(3-fluorobenzyl)amino]ethyl}quinolin-2-amine, CHLORIDE ION, ... | 著者 | Holden, J.K, Poulos, T.L. | 登録日 | 2016-06-18 | 公開日 | 2016-09-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.016 Å) | 主引用文献 | Targeting Bacterial Nitric Oxide Synthase with Aminoquinoline-Based Inhibitors. Biochemistry, 55, 2016
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7RJT
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![BU of 7rjt by Molmil](/molmil-images/mine/7rjt) | Aplysia Slo1 with Barium | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, BARIUM ION, BK channel, ... | 著者 | Zhu, J, Srivastava, S, Cachau, R, Holmgren, M. | 登録日 | 2021-07-21 | 公開日 | 2022-06-22 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | CryoEM structure of Aplysia Slo1 with 10 mM Ba2+ at 2.93 A To Be Published
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2C15
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![BU of 2c15 by Molmil](/molmil-images/mine/2c15) | 5-(4-Carboxy-2-oxo-butoxy)-4-oxo-pentanoic acid acid bound to Porphobilinogen synthase from Pseudomonas aeruginosa | 分子名称: | DELTA-AMINOLEVULINIC ACID DEHYDRATASE, MAGNESIUM ION | 著者 | Frere, F, Nentwich, M, Gacond, S, Heinz, D.W, Neier, R, Frankenberg-Dinkel, N. | 登録日 | 2005-09-11 | 公開日 | 2006-06-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors. Biochemistry, 45, 2006
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5G6B
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5DB7
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![BU of 5db7 by Molmil](/molmil-images/mine/5db7) | |