PDB: 36667 件ウェブページステータス検索Chemie searchBIRD

---

8F4B	Bovine multidrug resistance protein 1 (MRP1) bound to cyclic peptide inhibitor 1 (CPI1) 分子名称: Cyclic peptide inhibitor 1 (CPI1), Multidrug resistance-associated protein 1 著者 Pietz, H.L, Chen, J. 登録日 2022-11-10 公開日 2023-03-22 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 A macrocyclic peptide inhibitor traps MRP1 in a catalytically incompetent conformation. Proc.Natl.Acad.Sci.USA, 120, 2023
8BLR	G13D mutant of KRAS4b (2-169) bound to GDP with the switch-I in fully open conformation 分子名称: GTPase KRas, N-terminally processed, GUANOSINE-5'-DIPHOSPHATE 著者 Moche, M, Jungholm, O, Strandback, E, Ampah-Korsah, H, Nyman, T, Orwar, O. 登録日 2022-11-10 公開日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The 1.4 A crystal structure of K-Ras4A mutant G13D in open conformation To Be Published
8BLJ	Crystal structure of the ligand-binding domain (LBD) of human iGluR Delta-1 (GluD1), apo state 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Heroven, C, Malinauskas, T, Aricescu, A.R. 登録日 2022-11-09 公開日 2023-11-22 最終更新日 2024-01-03 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 GluD1 binds GABA and controls inhibitory plasticity. Science, 382, 2023
8F36	Ubx Homeodomain NMR solution structure 分子名称: Homeotic protein ultrabithorax 著者 Beasley, S.A, Loss, J.W, Mekkaoui, F, Advocate, M.R, Spratt, D.E. 登録日 2022-11-09 公開日 2023-04-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Ubx Homeodomain NMR solution structure To Be Published
8F37	AbdA Homeodomain NMR Solution Structure 分子名称: Homeobox protein abdominal-A 著者 Beasley, S.A, Simons, R.A, Advocate, M.R, Mekkaoui, F, Spratt, D.E. 登録日 2022-11-09 公開日 2023-04-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 AbdA Homeodomain NMR solution structure To Be Published
8BKH	Carboxymyoglobin dark state for comparison with power titration and 23 / 101 mJ/cm2 time series 分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Barends, T, Schlichting, I. 登録日 2022-11-09 公開日 2024-01-31 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8BKN	Carboxymyoglobin dark state for comparison with 5 mJ/cm2 time series 分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Barends, T, Schlichting, I. 登録日 2022-11-09 公開日 2024-01-31 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8F39	Yeast ATP synthase in conformation-2, at pH 6 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP synthase protein 8, ATP synthase subunit 4, ... 著者 Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M. 登録日 2022-11-09 公開日 2024-02-07 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling. Nat.Struct.Mol.Biol., 31, 2024
8HF0	DmDcr-2/R2D2/LoqsPD with 50bp-dsRNA in Dimer state 分子名称: Dicer-2, isoform A, LD06392p, ... 著者 Su, S, Wang, J, Wang, H.W, Ma, J. 登録日 2022-11-09 公開日 2023-09-06 実験手法 ELECTRON MICROSCOPY (3.72 Å) 主引用文献 Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers. Nat Commun, 14, 2023
8HF1	DmDcr-2/R2D2/LoqsPD with 19bp-dsRNA in Trimer state 分子名称: Dicer-2, isoform A, LD06392p, ... 著者 Su, S, Wang, J, Ma, J. 登録日 2022-11-09 公開日 2023-09-06 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers. Nat Commun, 14, 2023
8HF5	Cryo-EM structure of nucleotide-bound ComA at outward-facing state with EC gate open conformation 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transport/processing ATP-binding protein ComA 著者 Yu, L, Xin, X, Min, L. 登録日 2022-11-09 公開日 2023-10-04 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis of peptide secretion for Quorum sensing by ComA. Nat Commun, 14, 2023
8HF6	Cryo-EM structure of nucleotide-bound ComA E647Q mutant 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Competence factor transporting ATP-binding protein/permease ComA 著者 Yu, L, Xin, X, Min, L. 登録日 2022-11-09 公開日 2023-10-04 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of peptide secretion for Quorum sensing by ComA. Nat Commun, 14, 2023
8HF4	Cryo-EM structure of nucleotide-bound ComA at outward-facing state with EC gate closed conformation 分子名称: PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transport/processing ATP-binding protein ComA 著者 Yu, L, Xin, X, Min, L. 登録日 2022-11-09 公開日 2023-10-04 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis of peptide secretion for Quorum sensing by ComA. Nat Commun, 14, 2023
8HF7	Cryo-EM structure of ComA bound to its mature substrate CSP peptide 分子名称: Competence factor transporting ATP-binding protein/permease ComA, Competence-stimulating peptide type 1 著者 Yu, L, Xin, X, Min, L. 登録日 2022-11-09 公開日 2023-10-11 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of peptide secretion for Quorum sensing by ComA. Nat Commun, 14, 2023
8F2G	Crystal structure of Hen Egg White Lysozyme at 0.44 GPa 分子名称: Lysozyme C 著者 Marshall, A.C, Boer, S.A, Turner, G, Moggach, S.A, Bond, C.S, Vrielink, A. 登録日 2022-11-08 公開日 2022-12-07 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 High-pressure single-crystal diffraction at the Australian Synchrotron. J.Synchrotron Radiat., 30, 2023
8F2P	Nef SF2 dimerization mutant bound to Hck SH3 分子名称: C-terminal core protein, Tyrosine-protein kinase HCK 著者 Thomas, C.E, Alvarado, J.J, Smithgall, T.E. 登録日 2022-11-08 公開日 2023-02-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Neutron Reflectometry and Molecular Simulations Demonstrate HIV-1 Nef Homodimer Formation on Model Lipid Bilayers. J.Mol.Biol., 435, 2023
8F2K	Structure of yeast F1-ATPase determined with 100 micromolar cruentaren A 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ATP synthase subunit beta, ... 著者 Guo, H, Rubinstein, J.L. 登録日 2022-11-08 公開日 2023-04-05 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 CryoEM Structure with ATP Synthase Enables Late-Stage Diversification of Cruentaren A. Chemistry, 29, 2023
8HEG	Pentamer of FMDV (A/TUR/14/98) in complex with M3F 分子名称: M3F, VP1 of capsid protein, VP2 of capsid protein, ... 著者 Li, H.Z, Dong, H, Liu, P. 登録日 2022-11-08 公開日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural and in vivo studies of neutralizing antibody topographical classifications reveal mechanisms underlying differences in immunogenicity and antigenicity between 146S and 12S of foot-and-mouth disease virus To Be Published
8HEE	Pentamer of FMDV (A/TUR/14/98) 分子名称: VP1 of capsid protein, VP2 of capsid protein, VP3 of capsid protein 著者 Li, H.Z, Dong, H. 登録日 2022-11-08 公開日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural and in vivo studies of neutralizing antibody topographical classifications reveal mechanisms underlying differences in immunogenicity and antigenicity between 146S and 12S of foot-and-mouth disease virus To Be Published
8F28	Lysozyme Structures from Single-Entity Crystallization Method NanoAC 分子名称: ACETATE ION, CHLORIDE ION, Lysozyme C, ... 著者 Yang, R, Sankaran, B, Ogbonna, E, Wang, G. 登録日 2022-11-07 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 A Single-Entity Method for Actively Controlled Nucleation and High-Quality Protein Crystal Synthesis. Anal.Chem., 95, 2023
8F2B	Amylin 3 Receptor in complex with Gs and Pramlintide analogue peptide San45 分子名称: (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... 著者 Cao, J, Sexton, P.M, Wootten, D.L, Belousoff, M.J. 登録日 2022-11-07 公開日 2023-08-02 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (2 Å) 主引用文献 Structural insight into selectivity of amylin and calcitonin receptor agonists. Nat.Chem.Biol., 20, 2024
8F2A	Human Amylin3 Receptor in complex with Gs and Pramlintide analogue peptide San385 (Cluster 5 conformation) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Cao, J, Sexton, P.M, Wootten, D.L, Radostin, D. 登録日 2022-11-07 公開日 2023-08-02 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Structural insight into selectivity of amylin and calcitonin receptor agonists. Nat.Chem.Biol., 20, 2024
8F29	Yeast ATP synthase in conformation-1 at pH 6 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP synthase protein 8, ATP synthase subunit 4, ... 著者 Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M. 登録日 2022-11-07 公開日 2024-02-07 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling. Nat.Struct.Mol.Biol., 31, 2024
8BJT	Structure of human PLK1 in complex with 2-Allyl-1-[6-(1-hydroxy-1-methyl-ethyl)-pyridin-2-yl]-6-[4-(4-methyl-piperazin-1-yl)-phenylamino]-1,2-dihydro-pyrazolo[3,4-d]pyrimidin-3-one 分子名称: 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one, ACETATE ION, Serine/threonine-protein kinase PLK1, ... 著者 Musil, D, Liu-Bujalski, L. 登録日 2022-11-06 公開日 2023-04-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.188 Å) 主引用文献 Selective Wee1 Inhibitors Led to Antitumor Activity In Vitro and Correlated with Myelosuppression. Acs Med.Chem.Lett., 14, 2023
8BJU	HUMAN WEE1 KINASE IN COMPLEX WITH INHIBITOR 1-[6-(1-Hydroxy-1-methyl-ethyl)-pyridin-2-yl]-2-(2-methoxy-phenyl)-6-[4-(4-methyl-piperazin-1-yl)-phenylamino]-1,2-dihydro-pyrazolo[3,4-d]pyrimidin-3-one 分子名称: 2-(2-methoxyphenyl)-6-[[4-(4-methylpiperazin-1-yl)phenyl]amino]-1-[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]pyrazolo[3,4-d]pyrimidin-3-one, Wee1-like protein kinase 著者 Musil, D, Lan, R. 登録日 2022-11-06 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Selective Wee1 Inhibitors Led to Antitumor Activity In Vitro and Correlated with Myelosuppression. Acs Med.Chem.Lett., 14, 2023

<106107108109110111112113114115116117118119120121>