8F2K

Structure of yeast F1-ATPase determined with 100 micromolar cruentaren A

Summary for 8F2K

• Entry DOI: 10.2210/pdb8f2k/pdb
• EMDB information: 28818
• Descriptor: ATP synthase subunit alpha, ATP synthase subunit beta, ATP synthase subunit gamma, ... (6 entities in total)
• Functional Keywords: f1-atpase, atp synthase, cruentaren a, drug development, hydrolase
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Total number of polymer chains: 7
• Total formula weight: 342504.27

Authors

Guo, H.,Rubinstein, J.L. (deposition date: 2022-11-08, release date: 2023-04-05, Last modification date: 2024-04-24)

• Primary citation: Dou, X.,Guo, H.,D'Amico, T.,Abdallah, L.,Subramanian, C.,Patel, B.A.,Cohen, M.,Rubinstein, J.L.,Blagg, B.S.J.; CryoEM Structure with ATP Synthase Enables Late-Stage Diversification of Cruentaren A.; Chemistry, 29:e202300262-e202300262, 2023; PubMed: 36867738; DOI: 10.1002/chem.202300262

Experimental method

ELECTRON MICROSCOPY (2.9 Å)