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3CRI
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BU of 3cri by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ser, Glu82Asn and Lys101Ala
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
登録日2008-04-07
公開日2009-02-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
3CRH
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BU of 3crh by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ser and Lys101Ala
分子名称: Heparin-binding growth factor 1, SULFATE ION
著者Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
登録日2008-04-07
公開日2009-02-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
3KK6
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BU of 3kk6 by Molmil
Crystal Structure of Cyclooxygenase-1 in complex with celecoxib
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE, CITRATE ANION, ...
著者Sidhu, R.S.
登録日2009-11-04
公開日2009-12-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Coxibs interfere with the action of aspirin by binding tightly to one monomer of cyclooxygenase-1.
Proc.Natl.Acad.Sci.USA, 107, 2010
2KNX
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BU of 2knx by Molmil
Solution Structure of complement repeat CR17 from LRP-1
分子名称: CALCIUM ION, Prolow-density lipoprotein receptor-related protein 1
著者Guttman, M, Komives, E.
登録日2009-09-07
公開日2010-04-14
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure of the minimal interface between ApoE and LRP.
J.Mol.Biol., 398, 2010
1YQV
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BU of 1yqv by Molmil
The crystal structure of the antibody Fab HyHEL5 complex with lysozyme at 1.7A resolution
分子名称: Hen Egg White Lysozyme, HyHEL-5 Antibody Heavy Chain, HyHEL-5 Antibody Light Chain
著者Cohen, G.H, Silverton, E.W, Padlan, E.A, Dyda, F, Wibbenmeyer, J.A, Wilson, R.C, Davies, D.R.
登録日2005-02-02
公開日2005-04-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Water molecules in the antibody-antigen interface of the structure of the Fab HyHEL-5-lysozyme complex at 1.7 A resolution: comparison with results from isothermal titration calorimetry.
Acta Crystallogr.,Sect.D, 61, 2005
4H9K
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BU of 4h9k by Molmil
Crystal structure of cleavage site mutant of Npro of classical swine fever virus.
分子名称: Hog cholera virus, SULFATE ION, ZINC ION
著者Gottipati, K, Ruggli, N, Gerber, M, Tratschin, J.-D, Benning, M, Bellamy, H, Choi, K.H.
登録日2012-09-24
公開日2013-10-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献The Structure of Classical Swine Fever Virus N(pro): A Novel Cysteine Autoprotease and Zinc-Binding Protein Involved in Subversion of Type I Interferon Induction.
Plos Pathog., 9, 2013
3F9E
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BU of 3f9e by Molmil
Crystal Structure of the S139A mutant of SARS-Coronovirus 3C-like Protease
分子名称: 3C-like proteinase
著者Hu, T, Li, L, Jiang, H, Shen, X.
登録日2008-11-13
公開日2009-09-29
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure.
Virology, 388, 2009
2KJD
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BU of 2kjd by Molmil
Solution structure of extended PDZ2 domain from NHERF1 (150-270)
分子名称: Sodium/hydrogen exchange regulatory cofactor NHE-RF1
著者Bhattacharya, S, Cowburn, D, Bu, Z.
登録日2009-05-27
公開日2009-12-29
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A dynamic intramolecular conformational switch autoregulates the scaffolding protein NHERF1
To be Published
5AOO
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BU of 5aoo by Molmil
X-ray structure of a human Kobuvirus: Aichi virus A (AiV)
分子名称: VP0, VP1, VP3
著者Sabin, C, Palkova, L, Plevka, P.
登録日2015-09-11
公開日2016-03-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Use of Noncrystallographic Symmetry Averaging to Solve Structures from Data Affected by Perfect Hemihedral Twinning
Acta Crystallogr.,Sect.F, 72, 2016
5B2G
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BU of 5b2g by Molmil
Crystal structure of human claudin-4 in complex with C-terminal fragment of Clostridium perfringens enterotoxin
分子名称: Endolysin,Claudin-4, Heat-labile enterotoxin B chain
著者Shinoda, T, Kimura-Someya, T, Shirouzu, M, Yokoyama, S.
登録日2016-01-15
公開日2016-10-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis for disruption of claudin assembly in tight junctions by an enterotoxin
Sci Rep, 6, 2016
4HXQ
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BU of 4hxq by Molmil
Crystal structure of human Arginase-1 complexed with inhibitor 14
分子名称: Arginase-1, MANGANESE (II) ION, [(5R)-5-carboxy-5-(methylamino)-7-(piperidin-1-yl)heptyl](trihydroxy)borate(1-)
著者Cousido-Siah, A, Mitschler, A, Ruiz, F.X, Whitehouse, D.L, Golebiowski, A, Ji, M, Zhang, M, Beckett, P, Sheeler, R, Andreoli, M, Conway, B, Mahboubi, K, Schroeter, H, Van Zandt, M.C, Podjarny, A.
登録日2012-11-12
公開日2013-03-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Discovery of (R)-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury.
J.Med.Chem., 56, 2013
4K6M
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BU of 4k6m by Molmil
Crystal Structure of the full-length Japanese encephalitis virus NS5
分子名称: Polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
著者Lu, G, Gong, P.
登録日2013-04-16
公開日2013-08-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of the full-length Japanese encephalitis virus NS5 reveals a conserved methyltransferase-polymerase interface
Plos Pathog., 9, 2013
4LP8
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BU of 4lp8 by Molmil
A Novel Open-State Crystal Structure of the Prokaryotic Inward Rectifier KirBac3.1
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Inward rectifier potassium channel Kirbac3.1, ...
著者Zubcevic, L, Bavro, V.N, Muniz, J.R.C, Schmidt, M.R, Wang, S, De Zorzi, R, Venien-Bryan, C, Sansom, M.S.P, Nichols, C.G, Tucker, S.J.
登録日2013-07-15
公開日2013-11-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Control of KirBac3.1 Potassium Channel Gating at the Interface between Cytoplasmic Domains.
J.Biol.Chem., 289, 2014
2GBV
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BU of 2gbv by Molmil
C6A/C111A/C57A/C146A holo CuZn Superoxide dismutase
分子名称: COPPER (I) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Hornberg, A, Logan, D.T, Marklund, S.L, Oliveberg, M.
登録日2006-03-11
公開日2007-01-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Coupling between Disulphide Status, Metallation and Dimer Interface Strength in Cu/Zn Superoxide Dismutase
J.Mol.Biol., 365, 2007
3CQA
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BU of 3cqa by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ala and Lys101Ala
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
登録日2008-04-02
公開日2009-04-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
1P63
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BU of 1p63 by Molmil
Human Acidic Fibroblast Growth Factor. 140 Amino Acid Form with Amino Terminal His Tag and Leu111 Replaced with Ile (L111I)
分子名称: ACIDIC FIBROBLAST GROWTH FACTOR, FORMIC ACID, SULFATE ION
著者Brych, S.R, Kim, J, Logan, T.M, Blaber, M.
登録日2003-04-28
公開日2004-05-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Accommodation of a highly symmetric core within a symmetric protein superfold
Protein Sci., 12, 2003
4H9J
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BU of 4h9j by Molmil
Crystal structure of N-terminal protease (Npro) of classical swine fever virus.
分子名称: Hog cholera virus
著者Gottipati, K, Ruggli, N, Gerber, M, Tratschin, J.-D, Benning, M, Bellamy, H, Choi, K.H.
登録日2012-09-24
公開日2013-10-30
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The Structure of Classical Swine Fever Virus N(pro): A Novel Cysteine Autoprotease and Zinc-Binding Protein Involved in Subversion of Type I Interferon Induction.
Plos Pathog., 9, 2013
2KNY
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BU of 2kny by Molmil
Fusion construct of CR17 from LRP-1 and ApoE residues 130-149
分子名称: CALCIUM ION, LRP-1, linker, ...
著者Guttman, M, Komives, E.A.
登録日2009-09-08
公開日2010-04-14
最終更新日2020-02-26
実験手法SOLUTION NMR
主引用文献Structure of the minimal interface between ApoE and LRP.
J.Mol.Biol., 398, 2010
3F9G
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BU of 3f9g by Molmil
Crystal Structure of the F140A mutant of SARS-Coronovirus 3C-like Protease at pH 6.5
分子名称: 3C-like proteinase
著者Hu, T, Li, L, Jiang, H, Shen, X.
登録日2008-11-13
公開日2009-09-29
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure.
Virology, 388, 2009
4NUG
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BU of 4nug by Molmil
Crystal structure of HIV-1 broadly neutralizing antibody PGT151
分子名称: HEXAETHYLENE GLYCOL, PGT151 heavy chain, PGT151 light chain
著者Blattner, C, Wilson, I.A.
登録日2013-12-03
公開日2014-05-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8617 Å)
主引用文献Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers.
Immunity, 40, 2014
4O1O
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BU of 4o1o by Molmil
Crystal Structure of RNase L in complex with 2-5A
分子名称: Ribonuclease L, [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate
著者Huang, H, Zeqiraj, E, Ceccarelli, D.F, Sicheri, F.
登録日2013-12-16
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity.
Mol.Cell, 53, 2014
4NUJ
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BU of 4nuj by Molmil
Crystal structure of HIV-1 broadly neutralizing antibody PGT152
分子名称: PGT152 heavy chain, PGT152 light chain
著者Blattner, C, Wilson, I.A.
登録日2013-12-03
公開日2014-05-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.827 Å)
主引用文献Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers.
Immunity, 40, 2014
4O1P
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BU of 4o1p by Molmil
Crystal Structure of RNase L in complex with 2-5A and AMP-PNP
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonuclease L, ...
著者Huang, H, Zeqiraj, E, Ceccarelli, D.F, Sicheri, F.
登録日2013-12-16
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity.
Mol.Cell, 53, 2014
2R3E
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BU of 2r3e by Molmil
CRYSTAL STRUCTURE OF a ribokinase-like superfamily protein (EF1790) FROM ENTEROCOCCUS FAECALIS V583 AT 1.95 A RESOLUTION
分子名称: 1,2-ETHANEDIOL, YjeF-related protein
著者Joint Center for Structural Genomics (JCSG)
登録日2007-08-29
公開日2007-09-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of a putative kinase in the ribokinase-like superfamily from Enterococcus faecalis V583 (NP_815490.1) at 1.95 A resolution
To be published
2LUV
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BU of 2luv by Molmil
Structure and Binding Interface of the Cytosolic Tails of aXb2 Integrin
分子名称: Integrin alpha-X
著者Chua, G.L, Tang, X, Patra, T.A, Tan, S.M, Bhattacharjya, S.
登録日2012-06-21
公開日2012-07-04
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure and Binding Interface of the Cytosolic Tails of aXb2 Integrin
To be Published

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