4H9J

Crystal structure of N-terminal protease (Npro) of classical swine fever virus.

Summary for 4H9J

• Entry DOI: 10.2210/pdb4h9j/pdb
• Related: 4H9K
• Descriptor: Hog cholera virus (2 entities in total)
• Functional Keywords: npro, csfv, autoprotease, pestivirus, cysteine-protease, cysteine protease, irf-3 antagonist, irf-3, hydrolase
• Biological source: Classical swine fever virus
• Cellular location: Virion : Q68871
• Total number of polymer chains: 1
• Total formula weight: 17288.90

Authors

Gottipati, K.,Ruggli, N.,Gerber, M.,Tratschin, J.-D.,Benning, M.,Bellamy, H.,Choi, K.H. (deposition date: 2012-09-24, release date: 2013-10-30, Last modification date: 2018-01-24)

• Primary citation: Gottipati, K.,Ruggli, N.,Gerber, M.,Tratschin, J.D.,Benning, M.,Bellamy, H.,Choi, K.H.; The Structure of Classical Swine Fever Virus N(pro): A Novel Cysteine Autoprotease and Zinc-Binding Protein Involved in Subversion of Type I Interferon Induction.; Plos Pathog., 9:e1003704-e1003704, 2013; PubMed: 24146623; DOI: 10.1371/journal.ppat.1003704

Experimental method

X-RAY DIFFRACTION (1.6 Å)