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2NGR
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BU of 2ngr by Molmil
TRANSITION STATE COMPLEX FOR GTP HYDROLYSIS BY CDC42: COMPARISONS OF THE HIGH RESOLUTION STRUCTURES FOR CDC42 BOUND TO THE ACTIVE AND CATALYTICALLY COMPROMISED FORMS OF THE CDC42-GAP.
分子名称: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Nassar, N, Hoffman, G, Clardy, J, Cerione, R.
登録日1998-07-31
公開日1999-01-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP.
Nat.Struct.Biol., 5, 1998
1WRY
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Solution structure of the SH3 domain-binding glutamic acid-rich-like protein
分子名称: SH3 domain-binding glutamic acid-rich-like protein
著者Inoue, K, Miyamoto, K, Nagashima, T, Hayashi, F, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-10-29
公開日2005-04-29
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the SH3 domain-binding glutamic acid-rich-like protein
To be Published
7UFV
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BU of 7ufv by Molmil
Crystal structure of the WDR domain of human DCAF1 in complex with OICR-6766
分子名称: (3P)-N-[(1S)-3-amino-1-(3-chlorophenyl)-3-oxopropyl]-3-(2-fluorophenyl)-1H-pyrazole-4-carboxamide, DDB1- and CUL4-associated factor 1, UNKNOWN ATOM OR ION
著者Kimani, S, Li, A, Li, Y, Dong, A, Hutchinson, A, Seitova, A, Wilson, B, Al-Awar, R, Vedadi, M, Brown, P, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC)
登録日2022-03-23
公開日2022-05-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery of Nanomolar DCAF1 Small Molecule Ligands.
J.Med.Chem., 66, 2023
3VHL
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BU of 3vhl by Molmil
Crystal structure of the DHR-2 domain of DOCK8 in complex with Cdc42 (T17N mutant)
分子名称: Cell division control protein 42 homolog, Dedicator of cytokinesis protein 8, PHOSPHATE ION
著者Hanawa-Suetsugu, K, Kukimoto-Niino, M, Nishizak, T, Terada, T, Shirouzu, M, Fukui, Y, Yokoyama, S.
登録日2011-08-26
公開日2012-06-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.085 Å)
主引用文献DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses.
Blood, 119, 2012
1WGM
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BU of 1wgm by Molmil
Solution structure of the U-box in human ubiquitin conjugation factor E4A
分子名称: Ubiquitin conjugation factor E4A
著者Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-28
公開日2004-11-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the U-box in human ubiquitin conjugation factor E4A
To be Published
1AN0
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BU of 1an0 by Molmil
CDC42HS-GDP COMPLEX
分子名称: CDC42HS-GDP, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Kongsaeree, P, Cerione, R, Clardy, J.
登録日1997-06-26
公開日1999-01-13
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Structure Determination of Cdc42Hs and Gdp Complex
To be Published
7OLD
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BU of 7old by Molmil
Thermophilic eukaryotic 80S ribosome at pe/E (TI)-POST state
分子名称: 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ...
著者Kisonaite, M, Wild, K, Sinning, I.
登録日2021-05-19
公開日2022-01-26
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation.
Nat Commun, 13, 2022
7OLC
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Thermophilic eukaryotic 80S ribosome at idle POST state
分子名称: 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ...
著者Kisonaite, M, Wild, K, Sinning, I.
登録日2021-05-19
公開日2022-01-26
最終更新日2022-04-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation.
Nat Commun, 13, 2022
1AJE
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BU of 1aje by Molmil
CDC42 FROM HUMAN, NMR, 20 STRUCTURES
分子名称: CDC42HS
著者Feltham, J.L, Dotsch, V, Raza, S, Manor, D, Cerione, R.A, Sutcliffe, M.J, Wagner, G, Oswald, R.E.
登録日1997-05-02
公開日1997-11-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Definition of the switch surface in the solution structure of Cdc42Hs.
Biochemistry, 36, 1997
1CF4
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BU of 1cf4 by Molmil
CDC42/ACK GTPASE-BINDING DOMAIN COMPLEX
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, PROTEIN (ACTIVATED P21CDC42HS KINASE), ...
著者Mott, H.R, Owen, D, Nietlispach, D, Lowe, P.N, Lim, L, Laue, E.D.
登録日1999-03-23
公開日1999-06-18
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK.
Nature, 399, 1999
7PWG
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Cryo-EM structure of large subunit of Giardia lamblia ribosome at 2.7 A resolution
分子名称: 60S ribosomal protein L13, 60S ribosomal protein L18a, 60S ribosomal protein L27, ...
著者Hiregange, D.G, Rivalta, A, Bose, T, Breiner-Goldstein, E, Samiya, S, Cimicata, G, Kulakova, L, Zimmerman, E, Bashan, A, Herzberg, O, Yonath, A.
登録日2021-10-06
公開日2022-04-20
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia.
Nucleic Acids Res., 50, 2022
7PWO
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BU of 7pwo by Molmil
Cryo-EM structure of Giardia lamblia ribosome at 2.75 A resolution
分子名称: 40S ribosomal protein S21, 40S ribosomal protein S26, 40S ribosomal protein S30, ...
著者Hiregange, D.G, Rivalta, A, Bose, T, Breiner-Goldstein, E, Samiya, S, Cimicata, G, Kulakova, L, Zimmerman, E, Bashan, A, Herzberg, O, Yonath, A.
登録日2021-10-07
公開日2022-04-20
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia.
Nucleic Acids Res., 50, 2022
3ITE
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BU of 3ite by Molmil
The third adenylation domain of the fungal SidN non-ribosomal peptide synthetase
分子名称: CHLORIDE ION, SULFATE ION, SidN siderophore synthetase
著者Lee, T.V, Lott, J.S, Johnson, R.D, Johnson, L.J, Arcus, V.L.
登録日2009-08-28
公開日2009-11-17
最終更新日2014-02-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a eukaryotic nonribosomal peptide synthetase adenylation domain that activates a large hydroxamate amino acid in siderophore biosynthesis
J.Biol.Chem., 285, 2010
1CEE
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BU of 1cee by Molmil
SOLUTION STRUCTURE OF CDC42 IN COMPLEX WITH THE GTPASE BINDING DOMAIN OF WASP
分子名称: GTP-BINDING RHO-LIKE PROTEIN, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
著者Abdul-Manan, N, Aghazadeh, B, Liu, G.A, Majumdar, A, Ouerfelli, O, Rosen, M.K.
登録日1999-03-08
公開日1999-06-30
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein.
Nature, 399, 1999
1E0A
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BU of 1e0a by Molmil
Cdc42 complexed with the GTPase binding domain of p21 activated kinase
分子名称: Cell division control protein 42 homolog, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Morreale, A, Venkatesan, M, Mott, H.R, Owen, D, Nietlispach, D, Lowe, P.N, Laue, E.D.
登録日2000-03-16
公開日2000-04-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of Cdc42 Bound to the Gtpase Binding Domian of Pak
Nat.Struct.Biol., 7, 2000
1DOA
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BU of 1doa by Molmil
Structure of the rho family gtp-binding protein cdc42 in complex with the multifunctional regulator rhogdi
分子名称: GERAN-8-YL GERAN, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Hoffman, G.R, Nassar, N, Cerione, R.C.
登録日1999-12-20
公開日2000-02-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI.
Cell(Cambridge,Mass.), 100, 2000
1EES
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BU of 1ees by Molmil
SOLUTION STRUCTURE OF CDC42HS COMPLEXED WITH A PEPTIDE DERIVED FROM P-21 ACTIVATED KINASE, NMR, 20 STRUCTURES
分子名称: GTP-BINDING PROTEIN, P21-ACTIVATED KINASE
著者Gizachew, D, Guo, W, Chohan, K.C, Sutcliffe, M.J, Oswald, R.E.
登録日2000-02-02
公開日2000-03-29
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the complex of Cdc42Hs with a peptide derived from P-21 activated kinase.
Biochemistry, 39, 2000
1A4R
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BU of 1a4r by Molmil
G12V MUTANT OF HUMAN PLACENTAL CDC42 GTPASE IN THE GDP FORM
分子名称: AMINOPHOSPHONIC ACID-GUANYLATE ESTER, G25K GTP-BINDING PROTEIN, GUANOSINE-5'-DIPHOSPHATE, ...
著者Rudolph, M.G, Vetter, I.R, Wittinghofer, A.
登録日1998-02-02
公開日1999-03-02
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Nucleotide binding to the G12V-mutant of Cdc42 investigated by X-ray diffraction and fluorescence spectroscopy: two different nucleotide states in one crystal.
Protein Sci., 8, 1999
3A4R
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BU of 3a4r by Molmil
The crystal structure of SUMO-like domain 2 in Nip45
分子名称: 1,2-ETHANEDIOL, NFATC2-interacting protein, SULFATE ION
著者Sekiyama, N, Arita, K, Ikeda, Y, Ariyoshi, M, Tochio, H, Saitoh, H, Shirakawa, M.
登録日2009-07-14
公開日2010-02-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45
Proteins, 78, 2009
6XIQ
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BU of 6xiq by Molmil
Cryo-EM Structure of K63R Ubiquitin Mutant Ribosome under Oxidative Stress
分子名称: 18S ribosomal RNA, 35S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Zhou, Y, Bartesaghi, A, Silva, G.M.
登録日2020-06-21
公開日2020-08-26
最終更新日2020-09-23
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress.
Proc.Natl.Acad.Sci.USA, 117, 2020
1U0G
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BU of 1u0g by Molmil
Crystal structure of mouse phosphoglucose isomerase in complex with erythrose 4-phosphate
分子名称: BETA-MERCAPTOETHANOL, ERYTHOSE-4-PHOSPHATE, GLYCEROL, ...
著者Solomons, J.T.G, Zimmerly, E.M, Burns, S, Krishnamurthy, N, Swan, M.K, Krings, S, Muirhead, H, Chirgwin, J, Davies, C.
登録日2004-07-13
公開日2004-11-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structure of mouse phosphoglucose isomerase at 1.6A resolution and its complex with glucose 6-phosphate reveals the catalytic mechanism of sugar ring opening.
J.Mol.Biol., 342, 2004
1U0F
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Crystal structure of mouse phosphoglucose isomerase in complex with glucose 6-phosphate
分子名称: 6-O-phosphono-alpha-D-glucopyranose, BETA-MERCAPTOETHANOL, GLUCOSE-6-PHOSPHATE, ...
著者Solomons, J.T.G, Zimmerly, E.M, Burns, S, Krishnamurthy, N, Swan, M.K, Krings, S, Muirhead, H, Chirgwin, J, Davies, C.
登録日2004-07-13
公開日2004-11-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The crystal structure of mouse phosphoglucose isomerase at 1.6A resolution and its complex with glucose 6-phosphate reveals the catalytic mechanism of sugar ring opening.
J.Mol.Biol., 342, 2004
1U0E
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Crystal structure of mouse phosphoglucose isomerase
分子名称: BETA-MERCAPTOETHANOL, GLYCEROL, Glucose-6-phosphate isomerase, ...
著者Solomons, J.T.G, Zimmerly, E.M, Burns, S, Krishnamurthy, N, Swan, M.K, Krings, S, Muirhead, H, Chirgwin, J, Davies, C.
登録日2004-07-13
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The crystal structure of mouse phosphoglucose isomerase at 1.6A resolution and its complex with glucose 6-phosphate reveals the catalytic mechanism of sugar ring opening.
J.Mol.Biol., 342, 2004
6N8M
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Cryo-EM structure of pre-Lsg1 (PL) pre-60S ribosomal subunit
分子名称: 5.8S RNA, 5S rRNA, 60S ribosomal export protein NMD3, ...
著者Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W.
登録日2018-11-29
公開日2019-03-13
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
6N8N
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Cryo-EM structure of Lsg1-engaged (LE) pre-60S ribosomal subunit
分子名称: 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ...
著者Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W.
登録日2018-11-29
公開日2019-03-13
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019

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